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221 条记录 (耗时 0.064 秒)

    Preparation of saccharincarbonyl halides
    135.
    发明授权
    Preparation of saccharincarbonyl halides 失效
    糖精羰基卤化物的制备

    公开(公告)号：US5981758A

    公开(公告)日：1999-11-09

    申请号：US275802

    申请日：1999-03-25

    申请人： Peter Plath ,  Wolfgang von Deyn ,  Michael Rack ,  Ulf Misslitz

    发明人： Peter Plath ,  Wolfgang von Deyn ,  Michael Rack ,  Ulf Misslitz

    IPC分类号： C07C303/40 ,  C07C311/16 ,  C07D275/06

    CPC分类号： C07D275/06 ,  C07C303/40

    摘要： A process for preparing saccharincarbonyl halides of the formula 1 ##STR1## where: X is halogen,R.sup.1, R.sup.2 are each hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.1 -C.sub.4 -alkoxy, optionally C.sub.1 -C.sub.4 -alkyl-, fluorine- or C.sub.1 -C.sub.4 -alkoxy-substituted benzyl or phenyl,R.sup.3 is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl or phenyl or benzyl which is optionally mono- or polysubstituted by C.sub.1 -C.sub.4 -alkyl, halogen, C.sub.1 -C.sub.4 -haloalkyl or C.sub.1 -C.sub.4 -alkoxy,by reaction of an isophthalylsulfonamide 2 with an inorganic acid halide to give the saccharincarbonyl halide 1 ##STR2## is described.

    摘要翻译： 一种制备式1的糖精羰基卤化物的方法，其中：X是卤素，R 1，R 2各自是氢，C 1 -C 6烷基，C 3 -C 8环烷基，C 1 -C 4 - 烷氧基，任选地C 1 -C 4 - 烷基 - ，氟 - 或C 1 -C 4 - 烷氧基取代的苄基或苯基，R 3是氢，C 1 -C 6 - 烷基，C 3 -C 8 - 环烷基或苯基或苄基，其任选被C 1 -C 4 - 烷基，卤素， 通过间苯二酰基磺酰胺2与无机酰卤反应得到糖精羰基卤化物1，描述了C 4 - 卤代烷基或C 1 -C 4 - 烷氧基。

    Aniline type compounds
    137.
    发明授权
    Aniline type compounds 有权
    苯胺型化合物

    公开(公告)号：US09006485B2

    公开(公告)日：2015-04-14

    申请号：US14236362

    申请日：2012-08-10

    申请人： Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frasetto ,  Gemma Veitch ,  Markus Kordes ,  Marco Naujok

    发明人： Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frasetto ,  Gemma Veitch ,  Markus Kordes ,  Marco Naujok

    IPC分类号： C07C313/00 ,  A01N41/12 ,  A01N43/50 ,  A01N43/56 ,  A01N43/80 ,  C07D401/04 ,  C07C381/10 ,  C07D401/14 ,  C07D413/14 ,  C07D409/14 ,  A01N37/28

    CPC分类号： A01N43/56 ,  A01N37/28 ,  A01N41/12 ,  A01N43/50 ,  A01N43/80 ,  C07B2200/13 ,  C07C381/10 ,  C07D401/04 ,  C07D401/14 ,  C07D409/14 ,  C07D413/14

    摘要： The present invention relates to compounds of the formula (I) wherein R1 and R2 independently of one another are hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C10-cycloalkyl, C3-C10-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl or together represent an aliphatic chain, or the like; R3 is halogen, cyano, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C8-alkenyl, C2-C8-haloalkenyl, C1-C8-alkoxy, phenyl, or the like; R4 is hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula II with a compound of the formulae III or IV: where t, p, R1 R3, R3 and R4 are as defined in any of claims 1 to 6 and where A− is an equivalent of an anion having a pKB of at least 10 (determined under standard conditions in water).

    摘要翻译： 本发明涉及式（I）化合物，其中R 1和R 2彼此独立地是氢，C 1 -C 10 - 烷基，C 1 -C 10 - 卤代烷基，C 3 -C 10 - 环烷基，C 3 -C 10 - 卤代环烷基，C 2 -C 10 烯基，C 2 -C 10 - 卤代链烯基或一起代表脂族链等; R3是卤素，氰基，C1-C8-烷基，C1-C8-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C8-烯基，C2-C8-卤代烯基，C1-C8-烷氧基，苯基， 或类似物; R4是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基，苯基等; t为0或1; 本发明还涉及制备式（I）化合物的方法，其包括使式II化合物与式III或IV化合物反应：其中 t，p，R 1，R 3，R 3和R 4如权利要求1至6中任一项所定义，其中A-是pKB为至少10（在水中标准条件下测定）的阴离子的当量。

    Method for producing aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxylic acid amides
    139.
    发明授权
    Method for producing aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxylic acid amides 有权
    芳族和杂芳族羧酸，羧酸酯和羧酸酰胺的制备方法

    公开(公告)号：US08703992B2

    公开(公告)日：2014-04-22

    申请号：US12994271

    申请日：2009-05-25

    申请人： Nina Challand ,  Ansgar Gereon Altenhoff ,  Joachim Schmidt-Leithoff ,  Kathrin Wissel-Stoll ,  Michael Rack ,  Joachim Rheinheimer

    发明人： Nina Challand ,  Ansgar Gereon Altenhoff ,  Joachim Schmidt-Leithoff ,  Kathrin Wissel-Stoll ,  Michael Rack ,  Joachim Rheinheimer

    IPC分类号： C07C67/36

    CPC分类号： C07C231/10 ,  C07C51/10 ,  C07C67/36 ,  C07C63/04 ,  C07C69/76 ,  C07C235/84

    摘要： Process for the preparation of aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxamides by the reaction of aromatic or heteroaromatic halides R—Xn, in which n=integer from 1 to 6, R=substituted or unsubstituted and aromatic or heteroaromatic radical and X=chlorine, bromine or iodine atom, with carbon monoxide and water, ammonia, alcohols or amines in the presence of bases and zero-valent or divalent palladium compounds and bidentate diphosphanes or complexes of zero-valent or divalent palladium with bidentate diphosphanes, in which use is made of bidentate diphosphanes (R1—)(R2—)P—Y—P(—R3)(—R4) in which R1 to R4=unsubstituted aryl radicals or aryl radicals substituted with at least one radical exhibiting a positive resonance effect or a positive inductive effect, or unsubstituted or substituted cycloalkyl radicals, and Y=hydrocarbon group with a total of 2 to 20 carbon atoms, in which at least one of the carbon atoms carries only one or no hydrogen atom as substituent; except for the reaction of 4-bromo-3-difluoromethyl-1-methylpyrazole with 2-(3,4,5-trifluorophenyl)aniline and carbon monoxide to give N-[2-(3,4,5-trifluorophenyl)phenyl]-3-difluoromethyl-1-methylpyrazole-4-carboxamide.

    摘要翻译： 通过芳族或杂芳族卤化物R-Xn的反应制备芳族和杂芳族羧酸，羧酸酯和羧酰胺的方法，其中n = 1至6的整数，R =取代或未取代的芳族或杂芳族基团和X 在碱和零价或二价钯化合物和二价二膦或零价或二价钯与二齿二膦的配合物存在下，用一氧化碳和水，氨，醇或胺进行氯，溴或碘原子，其中 使用二价二膦（R1 - ）（R2-）P-Y-P（-R3）（ - R4），其中R1至R4 =未取代的芳基或被至少一个表现出正共振效应的基团取代的芳基 或正电感效应，或未取代或取代的环烷基，Y =总共2至20个碳原子的烃基，其中至少一个碳原子仅携带一个或不具有氢原子 原子作为取代基; 除了4-溴-3-二氟甲基-1-甲基吡唑与2-（3,4,5-三氟苯基）苯胺和一氧化碳反应，得到N- [2-（3,4,5-三氟苯基）苯基] -3-二氟甲基-1-甲基吡唑-4-甲酰胺。