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    Low Water Metal Ion Dentifrice
    142.
    发明申请
    Low Water Metal Ion Dentifrice 审中-公开
    低水金属离子牙粉

    公开(公告)号：US20140086851A1

    公开(公告)日：2014-03-27

    申请号：US14116371

    申请日：2011-06-02

    Applicant: Steven Fisher ,  Lynette Zaidel ,  Michael Prencipe

    Inventor： Steven Fisher ,  Lynette Zaidel ,  Michael Prencipe

    IPC: A61K8/81 ,  A61Q11/00

    CPC classification number: A61K8/8176 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/365 ,  A61K2800/48 ,  A61Q11/00

    Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients. The composition comprises a source of metal ions, an inorganic phosphate salt having four or more phosphorus atoms and a cross-linked polyvinylpyrrolidone thickening agent in a single phase. Preferred metal ions are stannous, copper and zinc, in particular from zinc citrate and stannous fluoride.

    Abstract translation: 具有低水相的洁齿剂组合物，其含有有效量的多磷酸盐和离子活性成分。 该组合物包含金属离子源，具有四个或更多个磷原子的无机磷酸盐和单相中的交联聚乙烯吡咯烷酮增稠剂。 优选的金属离子是亚锡，铜和锌，特别是柠檬酸锌和氟化亚锡。

    Dentifrice containing zinc ions and polyphosphate ions
    143.
    发明授权
    Dentifrice containing zinc ions and polyphosphate ions 有权
    含有锌离子和多磷酸根离子的牙粉

    公开(公告)号：US08628755B2

    公开(公告)日：2014-01-14

    申请号：US11668821

    申请日：2007-01-30

    Applicant: Michael Prencipe

    Inventor： Michael Prencipe

    IPC: A61K8/00

    CPC classification number: A61K8/27 ,  A61K8/0241 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/33 ,  A61K8/416 ,  A61K8/42 ,  A61K8/43 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/4953 ,  A61K8/4973 ,  A61K8/55 ,  A61K8/58 ,  A61K8/64 ,  A61K2800/412 ,  A61Q11/00

    Abstract: The invention includes a dentifrice composition that comprises a zinc ion source, a polyphosphate ion source, an anethole, and a silica. The silica has a mean particle size of about 5 to about 12 microns, an Einlehner hardness of about 1 to about 20, and an oil absorption of about 40 to less than about 100 cc/100 g. The composition contains zinc ions and polyphosphate ions in a weight ratio of about 0.1:1 to about 10:1 and has a RDA value of about 100 to about 200 and a PCR value of about 75 to about 110. Related methods are also included.

    Abstract translation: 本发明包括含有锌离子源，多磷酸盐离子源，茴香脑和二氧化硅的洁齿剂组合物。 二氧化硅具有约5至约12微米的平均粒度，约1至约20的爱因纳硬度，以及约40至小于约100cc / 100g的吸油量。 该组合物含有约0.1:1至约10:1的重量比的锌离子和多磷酸根离子，并且RDA值为约100至约200，PCR值为约75至约110.相关方法也包括在内。

    Oral care composition with cross-linked polymer peroxide
    146.
    发明授权
    Oral care composition with cross-linked polymer peroxide 有权
    口服护理组合物与交联聚合物过氧化物

    公开(公告)号：US08540971B2

    公开(公告)日：2013-09-24

    申请号：US12036674

    申请日：2008-02-25

    Applicant: Lynette Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

    Inventor： Lynette Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

    IPC: A61Q11/00 ,  A61K8/00 ,  A61K8/02 ,  A61K33/40

    CPC classification number: A61K8/8176 ,  A61K8/0208 ,  A61K8/22 ,  A61K8/24 ,  A61K8/49 ,  A61K8/817 ,  A61K8/891 ,  A61K8/90 ,  A61K2800/805 ,  A61Q11/00 ,  A61Q11/02

    Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

    Abstract translation: 口腔护理组合物，其包含：（a）包含过氧化物组分和N-乙烯基杂环聚合物（例如聚-N-乙烯基聚内酰胺或聚-N-乙烯基 - 聚酰亚胺）的过氧化物络合物; （b）增白剂（例如过氧化氢）; 和（c）口头可接受的承运人。 在一个实施方案中，载体包括成膜材料。 还提供了用于制备口腔护理组合物的方法，其包括：（a）将增白剂，硅氧烷粘合剂和载体流体混合以形成均匀的混合物; （b）向所述均匀混合物中加入过氧化物络合物，其中所述络合物包含过氧化氢和N-乙烯基杂环聚合物; 和（c）在真空下混合。

    Tooth whitening dental tray and method of use
    147.
    发明授权
    Tooth whitening dental tray and method of use 有权
    牙齿美白牙托和使用方法

    公开(公告)号：US08485821B2

    公开(公告)日：2013-07-16

    申请号：US12105065

    申请日：2008-04-17

    Applicant: Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

    Inventor： Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

    IPC: A61K6/00 ,  A61K8/22 ,  A61K8/25 ,  A61Q11/00

    CPC classification number: A61C19/066 ,  A61K8/18 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61Q11/00

    Abstract: A dental tray with a hydrophobic tooth whitening formulation where the tooth whitening formulation is substantially non-water soluble, and a method of using this dental tray to whiten the teeth. The tooth whitening formulation is primarily comprised of a hydrophobic polymer and a peroxide or a peroxide yielding compound. Preferably the hydrophobic polymer is the condensation product of a silicone resin and an organosiloxane. The dental tray is formed to encompass the front and the rear surfaces of the teeth. The dental tray is comprised of a thermoplastic or thermoset polymer. The teeth whitening formulation is placed into the dental tray and the tray placed against the teeth to be whitened. This is for a sufficient period of time to at least partially whiten teeth. This can be a period of time from about 0.5 hour to 2 hours or more. The substantially non-aqueous tooth whitening formulation is effective over a longer period of time since it is not significantly diluted or removed from the dental tray during the treatment time.

    Abstract translation: 具有疏水牙齿美白配方的牙科托盘，其中牙齿美白配方基本上是非水溶性的，以及使用该牙科托盘来使牙齿变白的方法。 牙齿美白制剂主要由疏水性聚合物和过氧化物或产生过氧化物的化合物组成。 优选地，疏水性聚合物是有机硅树脂和有机硅氧烷的缩合产物。 牙托被形成为包围牙齿的前表面和后表面。 牙科托盘由热塑性或热固性聚合物组成。 将牙齿美白配制剂放入牙托中，并将放置在牙齿上的托盘白化。 这是足够的时间来至少部分地美白牙齿。 这可以是约0.5小时至2小时或更长时间。 基本上非水性牙齿美白制剂在较长时间内是有效的，因为在治疗时间内没有显着稀释或从牙盘中除去。

    ORAL CARE COMPOSITION
    148.
    发明申请
    ORAL CARE COMPOSITION 有权
    口腔护理组合物

    公开(公告)号：US20130017240A1

    公开(公告)日：2013-01-17

    申请号：US13637370

    申请日：2010-03-31

    Applicant: Venda Porter ,  Andre Morgan ,  Michael Prencipe

    Inventor： Venda Porter ,  Andre Morgan ,  Michael Prencipe

    IPC: A61K8/02 ,  A61Q11/00 ,  A61K8/27 ,  A61K8/19 ,  A61K8/29

    CPC classification number: A61K8/27 ,  A61K8/0245 ,  A61K8/19 ,  A61K8/29 ,  A61K8/44 ,  A61K8/731 ,  A61K2800/412 ,  A61K2800/5922 ,  A61K2800/594 ,  A61K2800/624 ,  A61Q11/00

    Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.

    Abstract translation: 公开了口腔护理组合物，例如洁牙剂组合物，其包含口腔护理组合物，其包含口腔可接受的载体，平均粒度不大于牙本质小管的金属氧化物颗粒和能够螯合金属氧化物的至少一种氨基酸。 组合物可以包含用于将金属氧化物颗粒粘附在牙本质小管中的聚合物粘附材料。 金属氧化物颗粒的中值粒径为5微米以下，可以含有氧化锌。

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