公开(公告)号：US12168124B2

公开(公告)日：2024-12-17

申请号：US17752779

申请日：2022-05-24

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Jodi T. Dubuclet ,  Cory Brinkman

IPC: A61N1/05

Abstract: Stimulation lead includes an elongated lead body having distal and proximal ends and wire conductors extending therebetween. The stimulation lead also includes a lead paddle having a multi-dimensional array of electrodes positioned along a contact side of the lead paddle. The electrodes are electrically coupled to the wire conductors. The lead paddle includes a paddle body and a conductor organizer disposed within the paddle body. The conductor organizer has multiple channels extending along the lead paddle. The channels receive the wire conductors and retain the wire conductors in a designated arrangement with respect to the lead paddle. The conductor organizer has openings to the channels. The wire conductors extend through the openings and are terminated to the respective electrodes.

公开(公告)号：US12144984B2

公开(公告)日：2024-11-19

申请号：US16931030

申请日：2020-07-16

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Steven Boor ,  Daran DeShazo

IPC: A61N1/08 ,  A61B18/00 ,  A61M31/00 ,  A61N1/36 ,  A61N1/362 ,  A61N1/37 ,  A61N1/39 ,  A61N2/00 ,  H02M3/07 ,  H03K5/1252 ,  H03K5/24

Abstract: A system and method for measuring, monitoring and mitigating EMI interference in an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a diagnostic circuit is provided for sensing an interference voltage induced at a Kelvin connect electrode of the lead system, wherein the diagnostic circuit is configured to generate one or more control signals for adjusting in substantially real time a common-mode voltage reference provided to supply a biasing voltage to the IPG circuitry.

公开(公告)号：US20240366932A1

公开(公告)日：2024-11-07

申请号：US18774591

申请日：2024-07-16

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Ryan Sefkow ,  Christopher A. Crawford ,  Jeffrey Mitchell ,  Kevin Wilson ,  Raymond P. Bray ,  John R. Gonzalez

IPC: A61N1/05 ,  B29C45/00 ,  B29C45/14 ,  B29K75/00 ,  B29L31/00

Abstract: A method for fabricating a neurostimulation stimulation lead includes providing a plurality of ring components and hypotubes. An insulative coating is disposed on at least one of (i) inner surfaces of the ring components or (ii) the hypotubes. The method includes welding the hypotubes to the inner surfaces of the ring components, and molding an insulative material to fill interstitial spaces between the ring components and the hypotubes that are welded to form a stimulation tip component of the stimulation lead. The method includes forming segmented electrodes from the ring components after performing the molding.

公开(公告)号：US20240350798A1

公开(公告)日：2024-10-24

申请号：US18644071

申请日：2024-04-23

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Aaron Raines ,  Richard Ornelaz ,  Wei Carrigan

IPC: A61N1/05

CPC classification number: A61N1/0553

Abstract: The present application generally relates to neurostimulation systems with stimulation leads and/or stylets with improved malleability and/or flexibility.

公开(公告)号：US12121717B2

公开(公告)日：2024-10-22

申请号：US17893358

申请日：2022-08-23

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Timothy R. Deer

IPC: A61N1/05 ,  A61N1/06 ,  A61N1/36

CPC classification number: A61N1/0553 ,  A61N1/36071 ,  A61N1/36178 ,  A61N1/0558 ,  A61N1/06

Abstract: Implementations described and claimed herein provide paddle leads for dorsal root ganglia (DRG) stimulation and methods of implanting the same. In one implementation, the paddle lead has a small profile facilitating deployment into a target space in the neuroforamen dorsal to the DRG and below the vertebral lamina. A paddle body of the paddle lead may include a living hinge and/or a contoured profile to further facilitate implantation in the target space. For suture assisted deployment as well as to resist migration of the paddle lead once deployed, the paddle lead may include a suture loop configuration. The paddle lead further includes an electrode array having electrode contacts arranged in a two dimensional configuration pattern to create an electrical field optimized for stimulation of the DRG.

公开(公告)号：US20240221927A1

公开(公告)日：2024-07-04

申请号：US18540777

申请日：2023-12-14

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Daran DeShazo ,  Edward Lundberg

IPC: G16H40/40 ,  A61N1/02 ,  A61N1/08 ,  A61N1/372 ,  A61N1/378 ,  G16H40/67

CPC classification number: G16H40/40 ,  A61N1/025 ,  A61N1/08 ,  A61N1/37217 ,  A61N1/378 ,  G16H40/67

Abstract: A system and method of quantifying, maintaining and managing the functional status and/or therapy settings of an IMD based on code path metrics is disclosed. The codebase of device firmware modules may be instrumented to obtain tracing data and timing metrics data corresponding to different code paths that may be taken when a device subsystem or associated functionality is accessed or activated. Code path metrics of actual code paths may be analyzed to detect a deviation from baseline code path metrics and generate a corresponding graduated response.

公开(公告)号：US20240216686A1

公开(公告)日：2024-07-04

申请号：US18608885

申请日：2024-03-18

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Simeng Zhang ,  Hyun-Joo Park ,  Erika Ross

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/06 ,  A61N1/32

CPC classification number: A61N1/36034 ,  A61N1/0456 ,  A61N1/0492 ,  A61N1/06 ,  A61N1/323

Abstract: A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.

公开(公告)号：US20240149055A1

公开(公告)日：2024-05-09

申请号：US18413500

申请日：2024-01-16

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Aaron Raines

IPC: A61N1/05 ,  H01B13/00 ,  H01B13/008

CPC classification number: A61N1/05 ,  H01B13/0016 ,  H01B13/008 ,  A61B18/1492 ,  A61N1/0551

Abstract: A method of forming a stimulation lead includes forming an implantable lead body, including helically winding at least one cable about a mandrel to form a coiled cable assembly in a first, restrained state. Helically winding the at least one cable includes applying a tensile force to the at least one cable as the at least one cable is wound about the mandrel. Forming the lead body also includes releasing the tensile force from the at least one cable to allow the coiled cable assembly to release stored mechanical energy and transition from the restrained state to a second, relaxed state in which the coiled cable assembly is substantially free of stored mechanical energy. The method further includes subjecting the lead body to a reflow process by applying heat to the lead body, where the tensile force is released prior to the lead body being subjected to the reflow process.

公开(公告)号：US11964148B2

公开(公告)日：2024-04-23

申请号：US17190726

申请日：2021-03-03

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Jodi Townsley Dubuclet

IPC: A61N1/05

CPC classification number: A61N1/0553 ,  A61N1/05 ,  Y10T29/49002 ,  Y10T29/49117 ,  Y10T403/477

Abstract: A neurostimulation system is disclosed herein. The neurostimulation system includes an implantable pulse generator and an implantable therapy lead configured to be electrically coupled to the implantable pulse generator. The implantable therapy lead includes a flexible paddle electrode array with flexible electrodes. Each flexible electrode has a segmented configuration having first and second electrode segments and a flexible bridge or living hinge joining together the first and second electrode segments.

公开(公告)号：US20240082580A1

公开(公告)日：2024-03-14

申请号：US18515440

申请日：2023-11-21

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Steven Boor ,  Daran DeShazo

IPC: A61N1/36 ,  A61N1/08

CPC classification number: A61N1/36071 ,  A61N1/08 ,  A61N1/0456

Abstract: A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes. During a discharge operation, the control circuit is configured to manage the CR circuit to control a discharge current flow over the discharge operation to discharge the residual voltage after therapy delivery in a manner that follows an actively emulated passive discharge (AEPD) profile. During the discharge operation, the CR circuit is connected to the inactive electrode. The CR circuit receives, as a first input, an EMI feedback signal from the EMI antenna. The CR circuit is configured to regulate the discharge current flow through the active electrode based on the EMI feedback signal, to maintain the AEPD profile over the discharge operation while in a presence of an EMI event.