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1.发明授权公开(公告)号：US12280258B2
公开(公告)日：2025-04-22
申请号：US17566636
申请日：2021-12-30
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Nicole R. Hughes , Robert Nobles , Daran DeShazo , Betty Mark
Abstract: The present disclosure provides systems and methods for providing neurostimulation therapy according to patient features. The patient features may be analyzed to develop a patient model between physiological and/or patient reported features and optimal settings for a neurostimulation therapy using machine learning operations. The model is trained using data corresponding to time intervals in which electrical pulses are applied to the patient, including video kinematic data, patient reported pain levels, implanted or worn sensor patient data, and stimulation parameters. The model is used to control ongoing neurostimulation therapy for the patient.
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公开(公告)号：US20240216695A1
公开(公告)日：2024-07-04
申请号：US18609485
申请日：2024-03-19
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Daran DeShazo , Steven Boor
CPC classification number: A61N1/36153 , A61N1/3606 , A61N1/37235 , A61N1/378
Abstract: An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.
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公开(公告)号：US11969600B2
公开(公告)日：2024-04-30
申请号：US17355677
申请日：2021-06-23
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Daran DeShazo , Gavin Rade
CPC classification number: A61N1/37235 , A61N1/37223 , A61N1/378 , A61B5/367 , A61N1/36038 , A61N1/36053 , A61N1/36062 , A61N1/36082 , A61N1/362 , A61N1/38 , A61N1/39622 , A61N2/006
Abstract: An implantable medical device (IMD) includes one or more stimulation engines (SEs) and selectively connectable output switching circuitry for driving a plurality of output nodes associated with a respective plurality of electrodes of the IMD's lead system when implanted in a patient. The output switching circuitry may be configured to facilitate self-test mode (STM) functionality in the IMD (e.g., when it is in a hermetically sealed package) by using a dual mode switch in series with a stimulation engine selection switch with respect to each output node in the output switching circuitry under mode selection control.
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公开(公告)号：US11857789B2
公开(公告)日：2024-01-02
申请号：US17186630
申请日：2021-02-26
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Steven Boor , Daran DeShazo
CPC classification number: A61N1/36071 , A61N1/08 , A61N1/0452 , A61N1/0456 , A61N1/0534 , A61N1/0551
Abstract: A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes. During a discharge operation, the control circuit is configured to manage the CR circuit to control a discharge current flow over the discharge operation to discharge the residual voltage after therapy delivery in a manner that follows an actively emulated passive discharge (AEPD) profile. During the discharge operation, the CR circuit is connected to the inactive electrode. The CR circuit receives, as a first input, an EMI feedback signal from the EMI antenna. The CR circuit is configured to regulate the discharge current flow through the active electrode based on the EMI feedback signal, to maintain the AEPD profile over the discharge operation while in a presence of an EMI event.
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公开(公告)号：US11478644B2
公开(公告)日：2022-10-25
申请号：US16855212
申请日：2020-04-22
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Steven Boor , Daran DeShazo
Abstract: The present disclosure provides systems and methods for circuitry for an implantable pulse generator (IPG) of a neurostimulation system. The circuitry includes at least one anode node, at least one cathode node, a plurality of switching circuits, each switching circuit coupled to the at least one anode node and the at least one cathode node, and a plurality of output channels, each output channel coupled between an associated switching circuit and at least one electrode. The circuitry further includes a first DC blocking capacitor coupled between the at least one anode node and the plurality of switching circuits, a second DC blocking capacitor coupled between the at least one cathode node and the plurality of switching circuits. The circuitry further includes mitigation circuitry operable to limit DC leakage from the plurality of switching circuits through the plurality of output channels.
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Patent Agency Ranking
公开(公告)号：US11351376B2
公开(公告)日：2022-06-07
申请号：US16783837
申请日：2020-02-06
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Daran DeShazo , Steven Boor
Abstract: A system and method for extracting ETI load parametric data relative to one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme is provided for measuring induced voltages present at stimulated electrodes during a stimulation ramping sequence, which may be used for determining the ETI parametric data using a number of techniques, including, without limitation, a waveform analysis.
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公开(公告)号：US20210275805A1
公开(公告)日：2021-09-09
申请号：US16931030
申请日：2020-07-16
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Steven Boor , Daran DeShazo
IPC: A61N1/08 , H02M3/07 , H03K5/24 , H03K5/1252 , A61N1/36 , A61N1/362 , A61N1/37 , A61N1/39 , A61N2/00 , A61B18/00
Abstract: A system and method for measuring, monitoring and mitigating EMI interference in an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a diagnostic circuit is provided for sensing an interference voltage induced at a Kelvin connect electrode of the lead system, wherein the diagnostic circuit is configured to generate one or more control signals for adjusting in substantially real time a common-mode voltage reference provided to supply a biasing voltage to the IPG circuitry.
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公开(公告)号：US11071864B2
公开(公告)日：2021-07-27
申请号：US16189746
申请日：2018-11-13
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Steven Boor , Daran DeShazo
Abstract: An apparatus and method for providing split stimulation currents in a pulse generator. In one embodiment, a current regulator of the pulse generator includes a digitally-programmable analog voltage generator coupled to a first input of an error amplifier that receives a second input controlled by a programmable resistor network configured to control a programmable total stimulation current output. A plurality of current splitting switches are operative to split the programmable total stimulation current output into a corresponding plurality of split current segments, which may be individually mapped to a selected set of lead electrodes across one or more implantable leads associated with the pulse generator.
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9.发明申请公开(公告)号：US20200346005A1
公开(公告)日：2020-11-05
申请号：US16401971
申请日：2019-05-02
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Steven Boor , Daran DeShazo , Gavin L. Rade
Abstract: A neurostimulation (NS) system and method are provided. The system includes a power supply having positive and negative terminals. The negative terminal defines a reference ground. An array of electrodes are positioned within a patient. The array of electrodes includes first and second active electrodes for delivering stimulation therapy configured to be located proximate to neural tissue of interest that is associated with a target region. A control circuit is configured to control delivery of stimulation current for a NS therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the stimulation therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.
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公开(公告)号：US20240221926A1
公开(公告)日：2024-07-04
申请号：US18540773
申请日：2023-12-14
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Daran DeShazo , Edward Lundberg
Abstract: A system and method of quantifying, maintaining and managing the functional status and/or therapy settings of an IMD based on code path metrics is disclosed. The codebase of device firmware modules may be instrumented to obtain tracing data and timing metrics data corresponding to different code paths that may be taken when a device subsystem or associated functionality is accessed or activated. Code path metrics of actual code paths may be analyzed to detect a deviation from baseline code path metrics and generate a corresponding graduated response.
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