ELECTRODE DEVICES FOR NEUROSTIMULATION

    公开(公告)号:US20210085964A1

    公开(公告)日:2021-03-25

    申请号:US16634632

    申请日:2018-07-23

    Abstract: An extravascular neural interface is disclosed including a device containing electrodes for neurostimulation of a vessel. The devices are housed in flexible substrates forming two flaps, an inner flap having a spinal portion for routing leads/conductors into the device for connection to the electrodes and an outer flap that overlaps the inner flap. The inner flap supports and positions the electrodes to be inward facing, i.e., extravascular designs. The electrodes may be circular or elliptical and include a plurality of wings for securing the electrodes within a flap.

    NEUROMODULATION OF GANGLIA
    152.
    发明申请

    公开(公告)号:US20210069504A1

    公开(公告)日:2021-03-11

    申请号:US16771441

    申请日:2018-12-11

    Abstract: Modulation of neural activity of a ganglion, by applying a signal to a sympathetic nerve adjacent to the ganglion, results in preferential reduction of sympathetic signals to an effector, thereby providing ways of treating and preventing conditions associated with exacerbated sympatho-excitation.

    System for wirelessly coupling in vivo

    公开(公告)号:US10933248B2

    公开(公告)日:2021-03-02

    申请号:US15803405

    申请日:2017-11-03

    Abstract: Implantable systems are described that include a stimulation device positionable in vivo and configured to communicatively couple to electrodes configured to stimulate or block body tissue and an auxiliary device positionable in vivo and including one or more coils configured to wirelessly couple, in vivo, to the stimulation device and to wirelessly couple to an ex vivo device. The auxiliary device may include a coil driver and a power source controlled by a processor and memory for storing data instructions for the coil driver and for storing data received from the stimulation device. The auxiliary device may also include a radio transceiver and an antenna. The stimulation device may include a housing, a coil, a power source and an integrated circuit for controlling the electrodes. The stimulation device may be coupled to a cuff via a lead and physically coupled to the auxiliary device.

    ELECTRODE DEVICES FOR NEUROSTIMULATION
    154.
    发明申请

    公开(公告)号:US20200230421A1

    公开(公告)日:2020-07-23

    申请号:US16634620

    申请日:2018-07-23

    Abstract: An extravascular neural interface is disclosed containing electrodes for neurostimulation of the vessel. The devices are housed in flexible substrates, each substrate having a spinal portion for routing leads/conductors into the device for connection to the electrodes. Extending from opposite sides of the spinal portion is a self-sizing inner flap that supports and positions the electrodes to be inward facing, i.e., extravascular designs, and one more rigid outer flap. The electrodes may be flexible multifilar coil electrodes.

    ELECTRODE DEVICES FOR NEUROSTIMULATION
    155.
    发明申请

    公开(公告)号:US20200230399A1

    公开(公告)日:2020-07-23

    申请号:US16619396

    申请日:2018-07-23

    Abstract: An extravascular or intravascular neural interface is disclosed and can include three C-ring portions, with at least two including an electrode, an electrode pair or an electrode array. The portions are formed of a flexible material that is configured to enable the portions to self-size to fit around or against a surface of a target vessel when the neural interface is released at a position along the target vessel. A spinal portion configured to house electrical conductors for the electrodes is connected to one or more portions. The portions may be spaced sufficient apart to permit radial expansion and contraction of a target vessel around or within which the neural interface is placed, to reduce nerve compression, open trench low-pressure unrestricted blood-flow, and to enhance fluid exchange with the target vessel. The portions may be arranged in a low helix angle forming at least two full turns.

    Powering an in vivo device using energy from a radioactive source

    公开(公告)号:US10576172B2

    公开(公告)日:2020-03-03

    申请号:US15803496

    申请日:2017-11-03

    Abstract: An implantable system is disclosed that includes an encapsulated housing including a radioactive source. The encapsulated housing is internally coated with a light-generating coating that converts the radioactive energy to light, that is then output in vivo to a photodiode positioned proximate to at least part of the encapsulated housing in vivo. The photodiode is configured to generate electrical current from the light, which electrical current is output to a power conditioning circuit that is configured to use the electrical current as an input electrical current and to output power to a load in vivo. The encapsulated may also be internally coated, at least in part, with a light directing coating that causes light to be directed toward an optical lens that focuses the light on the photodiode. The radioactive source may be a gas having a low half-life and which poses no health risk to a patient if released.

    NEURAL INTERFACE FABRICATION
    159.
    发明申请

    公开(公告)号:US20190247645A1

    公开(公告)日:2019-08-15

    申请号:US16309182

    申请日:2017-06-12

    CPC classification number: A61N1/0556 A61B5/04001 A61B5/6846

    Abstract: Methods for fabricating implantable cuff electrodes for contacting or at least partially surrounding internal body tissue such as, e.g., nerves, smooth muscles, striated muscles, arteries, veins, ligamental tissues, connective tissues, cartilage tissues, bones, or other similar body tissues, structures and organs are disclosed. An example method includes preparing a substrate including an implantable cuff electrode shape, applying a mold material to the substrate, curing the mold material to form a mold, releasing the mold from the substrate, inserting at least one conductor into the mold that penetrates through the channel of the mold, pressing a formable material into the channel of the mold to form a body of an implantable cuff electrode about the at least one conductor, curing the body of the implantable cuff electrode, and releasing the body of the implantable cuff electrode from the mold.

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