公开(公告)号：US20220379298A1

公开(公告)日：2022-12-01

申请号：US17826595

申请日：2022-05-27

Applicant: Meso Scale Technologies, LLC.

Inventor： Manish KOCHAR

IPC: B01L3/00

Abstract: Devices and methods for multi-well plate liquid distribution are provided. Devices herein provide a plurality of dispensing stations configured to receive and dispense or disburse liquid to the wells of a multi-well plate. The dispensing stations include dispensing surfaces configured to receive liquid droplets dispensed by manual or automatic pipettes. The dispensing surfaces are configured to retain received liquids until force is applied and distribution to the wells of the multi-well plate occurs. Devices and methods provided herein increase the consistency of laboratory results in procedures requiring liquid distribution.

公开(公告)号：US20220252590A1

公开(公告)日：2022-08-11

申请号：US17553441

申请日：2021-12-16

Applicant: Meso Scale Technologies, LLC.

Inventor： Sudeep Kumar ,  George Sigal ,  Michael Tsionsky

IPC: G01N33/543 ,  G01N33/53 ,  C12Q1/6823 ,  C12Q1/6832 ,  C12Q1/6834

Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.

公开(公告)号：US20220196638A1

公开(公告)日：2022-06-23

申请号：US17563249

申请日：2021-12-28

Applicant: Meso Scale Technologies, LLC.

Inventor： Ian Chamberlin ,  Charles M. Clinton ,  Eli N. Glezer ,  Bandele Jeffrey-Coker ,  Manish Kochar ,  Sandor Kovacs ,  DT Le ,  Aaron Leimkuehler ,  Greg Pinckney ,  Kristian Roth ,  George Sigal ,  Fei Yin

IPC: G01N33/53 ,  B01L3/00 ,  G01N21/64 ,  G01N33/543 ,  G01N33/569

Abstract: We describe apparatuses, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of liquid samples in a clinical point of care setting.

公开(公告)号：US11315662B2

公开(公告)日：2022-04-26

申请号：US16594301

申请日：2019-10-07

Applicant: Meso Scale Technologies, LLC.

Inventor： Charles M. Clinton ,  Xinri Cong ,  Eli N. Glezer ,  Sudeep Kumar ,  Carl Stevens ,  Michael Vock ,  Jon S. Willoughby

IPC: G01N35/00 ,  G16C20/20 ,  G01N33/543 ,  B01L3/00 ,  G16H10/40 ,  G01N33/53

Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.

公开(公告)号：US11300571B2

公开(公告)日：2022-04-12

申请号：US16420724

申请日：2019-05-23

Applicant: Meso Scale Technologies, LLC

Inventor： Charles M. Clinton ,  Eli N. Glezer ,  Bandele Jeffrey-Coker ,  Sandor L. Kovacs ,  Sudeep M. Kumar ,  George Sigal ,  Carl Stevens ,  Michael Vock

IPC: B01L3/00 ,  G01N35/02 ,  G01N33/58 ,  B67B7/00 ,  G01N35/10 ,  G01N21/64 ,  G01N21/66 ,  G01N33/53 ,  G01N35/04

Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

公开(公告)号：US20220097072A1

公开(公告)日：2022-03-31

申请号：US17492207

申请日：2021-10-01

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Kenneth PAGE ,  Sandor KOVACS ,  Sudeep KUMAR ,  Kristian ROTH

IPC: B01L3/00 ,  F16K11/074

Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed.

公开(公告)号：US20210402390A1

公开(公告)日：2021-12-30

申请号：US17476880

申请日：2021-09-16

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Sudeep Kumar ,  Pankaj Oberoi ,  George Sigal ,  Michael Tsionsky

IPC: B01L3/00 ,  C12Q1/6876 ,  G01N33/543 ,  C12Q1/6816 ,  C12Q1/6804 ,  G01N33/68

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：USD939321S1

公开(公告)日：2021-12-28

申请号：US29767504

申请日：2021-01-22

Applicant: Meso Scale Technologies, LLC.

Designer： Aaron Leimkuehler ,  Rodger Darin Osborne ,  Jacob N. Wohlstadter

公开(公告)号：US20210364505A1

公开(公告)日：2021-11-25

申请号：US17394512

申请日：2021-08-05

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Anu Mathew

IPC: G01N33/543 ,  G01N33/574

Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

公开(公告)号：US20210291168A1

公开(公告)日：2021-09-23

申请号：US17215962

申请日：2021-03-29

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. GLEZER ,  Sudeep KUMAR ,  Pankaj OBEROI ,  George SIGAL ,  Michael TSIONSKY

IPC: B01L3/00 ,  C12Q1/6804 ,  G01N33/68 ,  G01N33/543 ,  C12Q1/6816 ,  C12Q1/6876

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.