公开(公告)号：US20130283733A1

公开(公告)日：2013-10-31

申请号：US13861502

申请日：2013-04-12

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B55/04

CPC classification number: B65B3/003 ,  B65B7/16 ,  B65B51/02 ,  B65B55/04 ,  B65B55/08 ,  B65B55/10 ,  B65B61/002 ,  B65B2039/009

Abstract: An apparatus and method for sterile filling comprises de-contaminating a needle penetrable surface of a device including a needle penetrable septum and a sealed chamber in fluid communication with the needle penetrable septum. A filling needle penetrates the needle penetrable septum, introduces substance through the filling needle and into the chamber and is, in turn, withdrawn from the septum. A liquid sealant is applied to the penetrated region of the septum. Radiation or energy is applied to the liquid sealant to cure the liquid sealant from a liquid phase to a solid phase.

Abstract translation: 用于无菌填充的装置和方法包括使包括针穿透隔膜的装置的针穿透表面和与针可穿透隔膜流体连通的密封室中的污染。 填充针穿透针穿透隔膜，通过填充针引入物质并进入腔室，然后从隔膜中取出。 将液体密封剂施加到隔膜的穿透区域。 将辐射或能量施加到液体密封剂以将液体密封剂从液相固化至固相。

公开(公告)号：US20130175299A1

公开(公告)日：2013-07-11

申请号：US13572145

申请日：2012-08-10

Applicant: Daniel Py ,  Joseph M. Ting

Inventor： Daniel Py ,  Joseph M. Ting

IPC: B65D83/00

CPC classification number: B65D83/0055 ,  A61F9/0008 ,  B05B11/00412 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3004 ,  B05B11/3074 ,  B05B11/3077 ,  B05B11/3092 ,  B05B11/3094 ,  B65D81/245

Abstract: A dispenser for dispensing a fluid includes a rigid vial that has a main fluid chamber containing a fluid, and a pump assembly that is in fluid communication with the main fluid chamber and is configured to dispense a predetermined quantity of fluid from the main fluid chamber. A flexible bladder is provided which is located within the main fluid chamber and is configured to expand to fill the ullage created within the main fluid chamber during dispensing of fluid by the pump assembly. The resilient bladder tends to force itself outwardly toward the rigid vial and, in turn, increases the pressure within the main fluid chamber in comparison to the interior of the bladder to thereby prevent the ingress of air or vapors through the bladder or otherwise into the main fluid chamber.

Abstract translation: 用于分配流体的分配器包括具有包含流体的主流体室的刚性小瓶和与主流体室流体连通并被构造成从主流体室分配预定量的流体的泵组件。 提供柔性囊，其位于主流体室内并且构造成膨胀以填充由泵组件分配流体期间在主流体室内产生的空位。 弹性气囊趋于朝向刚性小瓶向外强制，并且与气囊的内部相比增加了主流体室内的压力，从而防止空气或蒸气进入气囊或以其它方式进入主体 流体室。

公开(公告)号：US20130020321A1

公开(公告)日：2013-01-24

申请号：US13396053

申请日：2012-02-14

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65D55/00 ,  B65B7/00

CPC classification number: B29C67/004 ,  B29C45/006 ,  B29C45/1701 ,  B29C45/42 ,  B29C65/16 ,  B29C65/1616 ,  B29C66/001 ,  B29C66/0018 ,  B29C66/71 ,  B29C66/91212 ,  B29C66/91216 ,  B29C66/91221 ,  B29C66/91411 ,  B29C66/91431 ,  B29C66/961 ,  B29C2791/005 ,  B29L2031/565 ,  B65B3/003 ,  B65B3/022 ,  B65B55/06 ,  B29C65/00 ,  B29K2023/38

Abstract: A stopper and container body are molded in the same molding machine. An assembly device, such as a pick and place robot, transfers the stopper from one mold cavity into the opening in the container body located within another mold cavity, or vice versa, to assemble the stopper and container body. Then, the assembled container body and stopper are removed from the molding machine and transported to a needle filling and laser resealing station for filling and laser resealing. A laminar flow source directs a substantially laminar flow of air or sterile gas over the mold surfaces, stoppers and container bodies, and assembly device, to prevent contamination during assembly.

Abstract translation: 塞子和容器主体在相同的成型机中成型。 诸如拾放机器人的组装装置将止动器从一个模腔转移到位于另一个模腔内的容器主体中的开口中，反之亦然，以组装止动器和容器主体。 然后，将组装的容器主体和止动件从成型机中取出并输送到针填充和激光重新密封站，用于填充和激光重新密封。 层流源将空气或无菌气体的基本层流引导到模具表面，塞子和容器主体以及组装装置上，以防止组装过程中的污染。

公开(公告)号：US20130008137A1

公开(公告)日：2013-01-10

申请号：US13529951

申请日：2012-06-21

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B55/02

CPC classification number: B65B55/10 ,  B65B25/001 ,  B65B25/008

Abstract: A method for sterilizing a container is provided where a penetrable septum of a sealed empty device is penetrated with an injection member. A fluid sterilant is then injected through the injection member and into an interior chamber of the device. The fluid sterilant is allowed to reside within the chamber a sufficient amount of time to render the chamber either sterile or bactericidal. Product can then be introduced through the septum into the sterile or bactericidal chamber. The resulting penetration aperture is then resealed to hermetically seal the product within the chamber.

Abstract translation: 提供了一种用于对容器进行灭菌的方法，其中密封的空装置的可穿透的隔膜用注射构件穿透。 然后将流体灭菌剂通过注射构件注入装置的内部室中。 允许流体灭菌剂在室内停留足够的时间以使得室无菌或杀菌。 然后将产品通过隔膜引入无菌或杀菌室。 然后将所得到的穿透孔重新密封以将产品气密密封在腔室内。

公开(公告)号：USD667559S1

公开(公告)日：2012-09-18

申请号：US29400406

申请日：2011-08-26

Applicant: Daniel Py

Designer： Daniel Py

公开(公告)号：US20120152881A1

公开(公告)日：2012-06-21

申请号：US13329483

申请日：2011-12-19

Applicant: Daniel Py ,  Debashis Sahoo ,  Norbert M. Assion ,  Julian V. Chan

Inventor： Daniel Py ,  Debashis Sahoo ,  Norbert M. Assion ,  Julian V. Chan

IPC: A61J9/00

CPC classification number: A61J9/00 ,  A61J1/2093

Abstract: A container including a body defining an outflow opening and at least one chamber adapted for storing a product, such as a fat containing liquid product, and a container closure including a primary seal for hermetically sealing the product within the chamber during storage. The container closure includes a sealing member forming a substantially fluid-tight seal between the container closure and the body, and a dispensing member in fluid communication with the chamber. The container closure and body move relative to each other between a first position where the primary seal is seated about the outflow port to hermetically seal the product in the chamber during storage, and a second position where the primary seal is displaced from the outflow port to allow product to pass from the chamber through the outflow port and into dispensing member to dispense the product.

Abstract translation: 一种容器，其包括限定流出开口的主体和适于储存产品（例如含脂肪的液体产品）的至少一个室，以及包含用于在储存期间气密地密封室内的产品的主密封件的容器盖。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件和与腔室流体连通的分配构件的密封构件。 容器封闭件和主体在第一位置和第二位置之间移动，第一位置和第二位置之间，第一位置处主要密封件围绕流出端口安置，以便在存储期间将产品气密地密封在腔室中;以及第二位置，其中主密封件从流出端口移位到 允许产品从腔室通过流出口并进入分配构件以分配产品。

公开(公告)号：US08163251B2

公开(公告)日：2012-04-24

申请号：US10241249

申请日：2002-09-10

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61L2/04 ,  B65G25/00 ,  B66C17/08 ,  B65B11/52 ,  B65B53/00

CPC classification number: B65B31/024 ,  A61L2/04 ,  A61L2/081 ,  A61L2/087 ,  A61L2/26 ,  A61L2202/122 ,  A61L2202/182 ,  B65B5/045 ,  B65B7/02 ,  B65B55/02 ,  B65B55/08 ,  B65B55/16 ,  B65B69/0033 ,  B65B69/0066

Abstract: A sterile enclosure contains a transfer module defining a window. A port covers the window to maintain the inside of the enclosure as a sealed and sterile environment. A sliding, heated cutting element mounted on the port serves to sterilize and sever a portion of a sterile transfer bag assembly attached to the port. Preferably, the excised portion of the sterile transfer bag assembly is affixed to the port when the port opens. The sliding cutting element remains extended and heated to prevent contamination when the port is open. Further, a heating element is mounted about the window in order to sterilize around the opening when the port is open.

Abstract translation: 无菌外壳包含定义窗口的传输模块。 端口覆盖窗口，以将密封和无菌环境保持在外壳内部。 安装在端口上的滑动加热切割元件用于对连接到端口的无菌转移袋组件的一部分进行消毒和切断。 优选地，当端口打开时，无菌转移袋组件的切除部分被固定到端口。 滑动切割元件保持延伸和加热，以防止端口打开时的污染。 此外，加热元件安装在窗口周围，以便在端口打开时围绕开口消毒。

公开(公告)号：US20120076883A1

公开(公告)日：2012-03-29

申请号：US13311616

申请日：2011-12-06

Applicant: Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Giovanni Rodriguez

Inventor： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Giovanni Rodriguez

IPC: B29C45/18

CPC classification number: B29C45/1701 ,  B29C37/0007 ,  B29C45/006 ,  B29C45/1753 ,  B29C45/40 ,  B29C45/42 ,  B29C2045/1797 ,  B29C2791/005

Abstract: At least one of first and second mold portions defines a mold cavity to receive molten plastic and form therefrom at least one molded part, and is movable relative to the other between (i) a closed position for sealing the mold cavity or cavities and molding at least one part therein, and (ii) an open position defining a fluid passageway between the mold portions and permitting the passage of a fluid sterilant therein. A fluid sterilant source is connectable in fluid communication with the fluid passageway for introducing the sterilant therein in the open position, contacting with the sterilant the surfaces of the first and second mold portions forming the fluid passageway and located adjacent to the at least one mold cavity, but not contacting an interior surface of a molded part within the mold cavity, to sterilize the exposed mold surfaces and thereby prevent contamination of the molded part.

Abstract translation: 第一和第二模具部分中的至少一个限定了模腔以接收熔融塑料并从其形成至少一个模制部件，并且可以在（i）用于密封模腔或空腔的闭合位置和相对于另一模制部件 其中至少一部分，以及（ii）在模具部分之间限定流体通道并允许其中的流体灭菌剂通过的打开位置。 流体灭菌剂源可连接到流体通道，用于将灭菌剂在其中引入打开位置，与杀菌剂接触，形成第一和第二模具部分的形成流体通道的表面并且邻近于至少一个模腔 但是不与模腔内的模制部件的内表面接触，对暴露的模具表面进行消毒，从而防止模制部件的污染。

公开(公告)号：US08132600B2

公开(公告)日：2012-03-13

申请号：US12894224

申请日：2010-09-30

Applicant: Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

Inventor： Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

IPC: B65B1/04

CPC classification number: B65B55/10 ,  B65B3/003 ,  B65B7/2842 ,  B65B51/22 ,  B65B55/025 ,  B65D51/002 ,  B65D51/18 ,  B65D2251/0015 ,  B65D2251/0078

Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

Abstract translation: 提供容器和方法来储存含有液体产品的脂肪。 容器包括限定用于接收产品的储存室的主体和容器封闭件。 第一材料部分形成至少大部分覆盖储存室的表面区域，该表面区域可接触其中的任何产品。 身体和第一材料部分都不会将超过预定量的可浸出物浸入产品中或者不期望地改变其味道特征。 针可穿透和可热再密封的第二材料部分（i）覆盖在第一材料部分上并且不能接触储存室内的任何产品，或（ii）形成覆盖存储室的基本上较小的表面区域，其可以与其中的任何产品接触 到第一材料部分。 密封部分可与主体接合以在容器封闭件和主体之间形成基本上干燥的气密密封。

公开(公告)号：US20110272033A1

公开(公告)日：2011-11-10

申请号：US13102884

申请日：2011-05-06

Applicant: Daniel Py

Inventor： Daniel Py

IPC: F16K11/044

CPC classification number: F16K15/145 ,  B65D47/2018 ,  B65D47/2031 ,  B65D77/065 ,  B65D83/0055 ,  F16K15/02 ,  F16K15/142 ,  Y10T137/0318 ,  Y10T137/0396 ,  Y10T137/4245 ,  Y10T137/7879 ,  Y10T137/7889 ,  Y10T137/86895

Abstract: A one-way valve is connectable in fluid communication with a fluid-receiving chamber, such as a dilution chamber or a mixing chamber for diluting or mixing a perishable food product, such as a milk product or chocolate product, and forming a substantially fluid-tight seal therebetween. The valve comprises a relatively rigid valve seat, and a relatively flexible valve member overlying the valve seat and forming an axially-elongated, normally-closed valve opening therebetween defining an inlet at one end of the valve seat, an outlet at an opposite end of the valve seat, and an axially-extending seal therebetween that forms a fluid-tight seal between the inlet and outlet of the normally-closed valve opening. An axially-extending valve body is radially spaced relative to the valve member and forms a space therebetween allowing fluid-flow therethrough for cleaning the valve and the fluid-receiving chamber. A seal is engageable with the fluid-receiving chamber and forms a substantially fluid-tight seal therebetween to seal the valve outlet and fluid-receiving chamber with respect to ambient atmosphere. The valve member is movable radially away from the valve seat in response to substance at the inlet to the valve opening exceeding a valve opening pressure to flow into the normally closed valve opening, through the outlet, and into the fluid-receiving chamber.

Abstract translation: 单向阀可连接到流体接收室，例如稀释室或混合室，用于稀释或混合易腐食品，例如乳制品或巧克力产品，并形成基本上流体的流体， 密封。 该阀包括相对刚性的阀座和相对柔性的阀构件，该阀构件覆盖在阀座上并形成一个轴向细长的常闭阀门开口，在其间形成一个位于阀座一端的入口， 阀座和其间的轴向延伸的密封件，其在常闭阀开口的入口和出口之间形成流体密封。 轴向延伸的阀体相对于阀构件径向间隔开并在其间形成一个空间，允许流体流过其中以清洁阀和流体接收室。 密封件可与流体接收室接合并且在其间形成基本上流体密封的密封件，以相对于环境大气密封阀出口和流体接收室。 阀构件响应于阀开口处的物质超过阀开启压力而径向地远离阀座移动，以通过出口流入常闭阀开口并进入流体接收室。