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公开(公告)号:US20200345497A1
公开(公告)日:2020-11-05
申请号:US16935555
申请日:2020-07-22
发明人: Brian S. Conklin
摘要: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.
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公开(公告)号:US20200289257A1
公开(公告)日:2020-09-17
申请号:US16888649
申请日:2020-05-29
发明人: Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, JR.
摘要: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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公开(公告)号:US20200253601A1
公开(公告)日:2020-08-13
申请号:US16859946
申请日:2020-04-27
摘要: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.
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公开(公告)号:US10463485B2
公开(公告)日:2019-11-05
申请号:US15481283
申请日:2017-04-06
发明人: Brian S. Conklin , Michael C. Murad
IPC分类号: A61F2/24
摘要: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.
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公开(公告)号:US20190167422A1
公开(公告)日:2019-06-06
申请号:US16270849
申请日:2019-02-08
发明人: Jessica Guttenberg , Da-Yu Chang , Derrick Johnson , Brian S. Conklin , Qinggang Zeng , Myron Howanec, JR. , Grace Myong Kim
IPC分类号: A61F2/24
摘要: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.
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公开(公告)号:US20190021854A1
公开(公告)日:2019-01-24
申请号:US16141604
申请日:2018-09-25
发明人: Brian S. Conklin , Da-Yu Chang
IPC分类号: A61F2/24
摘要: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.
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公开(公告)号:US20180221016A1
公开(公告)日:2018-08-09
申请号:US15944337
申请日:2018-04-03
CPC分类号: A61B17/0487 , A61B17/0401 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0416 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2442
摘要: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.
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公开(公告)号:US20170281340A1
公开(公告)日:2017-10-05
申请号:US15617906
申请日:2017-06-08
发明人: Jessica Guttenberg , Da-Yu Chang , Derrick Johnson , Brian S. Conklin , Qinggang Zeng , Myron Howanec, JR. , Grace Myong Kim
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2250/0085 , A61F2250/0089 , A61F2250/0098
摘要: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.
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公开(公告)号:US20170258585A1
公开(公告)日:2017-09-14
申请号:US15452617
申请日:2017-03-07
发明人: Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, JR.
CPC分类号: A61F2/2409 , A61B5/0031 , A61B5/026 , A61B5/4851 , A61B5/686 , A61B2562/0261 , A61F2/2412 , A61F2/2418 , A61F2/2445 , A61F2210/0076 , A61F2230/0069 , A61F2240/00
摘要: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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公开(公告)号:US20170000604A1
公开(公告)日:2017-01-05
申请号:US15199748
申请日:2016-06-30
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2210/0057 , A61F2220/0075 , A61F2230/0069 , A61F2250/001 , A61F2250/0018 , A61F2250/0048 , A61F2250/006 , A61F2250/0097
摘要: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.
摘要翻译: 公开了一种假体心脏瓣膜,其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 假体心脏瓣膜可以被构造成当最初植入时具有大致刚性和/或抗膨胀的构造,以替代天然瓣膜(或其他假体心脏瓣膜),但是当受到向外的力(例如, 由膨胀气球或其他机械膨胀机提供。 流入支架框架是可扩张的,用于将阀固定在适当位置,并且可以具有在有限程度上可折叠的流出端,用于输送和可扩展的植入后可促进阀门(ViV)程序。 混合心脏瓣膜消除了早期的结构带,这既减少了制造时间又促进了ViV程序。
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