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公开(公告)号：US20160143739A1
公开(公告)日：2016-05-26
申请号：US14950637
申请日：2015-11-24
CPC分类号： A61F2/2487 , A61F2/2412 , A61F2/2418 , A61F2220/0008 , A61M1/1008 , A61M1/1037 , A61M1/1053 , A61M1/1058 , A61M1/106 , A61M1/1098 , A61M1/122 , A61M2205/0283
摘要： An implantable heart system for the treatment of a heart with impaired function. The implantable heart system includes a prosthetic heart chamber assembly and a cooperative mechanism. The prosthetic heart chamber assembly comprises a first prosthesis, a second prosthesis, and a prosthetic heart chamber interconnecting the first and second prostheses. One of the prostheses is a valve and the other prosthesis is either a valve or a tubular prosthesis. The cooperative mechanism is selected from the group consisting of an adhesive; an anchor; a filler material; a shape memory element; an expandable member; a pumping agent; material attached to, or forming a part of, the wall of the prosthetic heart chamber; and combinations thereof.
摘要翻译： 用于治疗功能受损的心脏的可植入心脏系统。 可植入心脏系统包括假体心脏室组件和协作机构。 假体心室组件包括第一假体，第二假体和互连第一和第二假体的假体心室。 假体中的一个是阀，另一个假体是阀或管状假体。 协同机构选自粘合剂; 锚点 填料; 形状记忆元件; 可扩展构件; 泵送剂; 附着于或形成假体心脏室的壁的一部分的材料; 及其组合。
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公开(公告)号：US20150297813A1
公开(公告)日：2015-10-22
申请号：US14440848
申请日：2013-11-05
CPC分类号： A61M1/122 , A61M1/1005 , A61M1/101 , A61M1/1086 , A61M1/1098 , A61M1/12 , A61M1/125 , A61M1/127
摘要： Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports.
摘要翻译： 公开了配置成与天然心脏串联操作的机械循环支撑件。 在一个实施例中，使用离心泵。 在一个实施例中，入口和出口连接到主动脉中，并且血流通过入口和出口之间的内腔和离心泵转向。
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公开(公告)号：US20150039076A1
公开(公告)日：2015-02-05
申请号：US13959047
申请日：2013-08-05
申请人： Bret J. Park
发明人： Bret J. Park
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/82 , A61M1/1096 , A61M1/1098 , A61M1/12 , A61M1/122
摘要： A medical device used in patients with inefficient heart function to improve the efficiency of the pumping action of the heart. This device adds one or more one-way valves in the blood vessels and/or arteries, very near, but not in, the heart, thereby increasing the efficiency of the native heart. The device includes one or more one-way heart valves designed to go in arteries/veins that are connected to the heart, and which arteries and/or veins are the conduits for taking blood into/out of the heart. The one-way heart valve allows blood flow in only one direction. An optional sleeve (stent) may be placed outside the arteries/veins where the valve(s) are located to add support to the walls. An optional sleeve (stent) may also be used on the inside of the artery to insure the artery does not collapse during a vacuum phase of the beating.
摘要翻译： 用于心脏功能低下的患者的医疗设备，以提高心脏的泵送作用的效率。 该装置在血管和/或动脉中添加一个或多个单向阀，非常接近但不在心脏中，从而增加天然心脏的效率。 该装置包括设计成进入与心脏连接的动脉/静脉中的一个或多个单向心脏瓣膜，以及哪些动脉和/或静脉是用于将血液进入/离开心脏的导管。 单向心脏瓣膜仅允许血液流向一个方向。 可选的套管（支架）可以放置在阀门所在的动脉/静脉的外部，以增加对壁的支撑。 也可以在动脉内侧使用可选的套管（支架），以确保在打浆的真空阶段动脉不会塌陷。
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154.发明申请公开(公告)号：US20140288355A1
公开(公告)日：2014-09-25
申请号：US14354922
申请日：2012-10-31
申请人： BERLIN HEART GMBH
CPC分类号： A61M1/1008 , A61M1/1098 , A61M1/12 , A61M1/122
摘要： A connecting element for connecting a blood pump or a cannula to a heart, the connecting element including a sealing element, which is designed to at least temporarily close an opening formed in the cardiac wall and to be opened via insertion of a preferably cylindrical object in the direction of an axis of the opening.
摘要翻译： 用于将血液泵或套管连接到心脏的连接元件，所述连接元件包括密封元件，所述密封元件被设计成至少暂时封闭形成在所述心脏壁中的开口并且通过将优选圆柱形物体插入 开口轴线的方向。
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155.发明授权公开(公告)号：US08771164B2
公开(公告)日：2014-07-08
申请号：US13739416
申请日：2013-01-11
IPC分类号： A61M1/12
CPC分类号： A61M1/12 , A61M1/1008 , A61M1/101 , A61M1/1025 , A61M1/1037 , A61M1/106 , A61M1/1098 , A61M1/122 , Y10T29/49236 , Y10T29/49826
摘要： A ventricular assist device (VAD) having static seal structure for a pump housing which includes a support structure, a first sealing element, and a second sealing element. The support structure circumscribes a pump chamber and includes a first sealing surface, an opposing second sealing surface, and a fluid transfer end interposed between the sealing surfaces. The support structure provides a fluid flow path running through the fluid transfer end and into the pump chamber via an inlet bore and from the pump chamber back through the fluid transfer end via an outlet bore. The first sealing element is disposed on the first sealing surface, and the second sealing element is disposed on the second sealing surface. The sealing elements are configured for forming sealing interfaces in the pump housing, establishing a static seal that isolates the pump chamber from an environment external to the fluid pump housing.
摘要翻译： 一种具有用于泵壳体的静态密封结构的心室辅助装置（VAD），其包括支撑结构，第一密封元件和第二密封元件。 支撑结构包围泵室，并且包括第一密封表面，相对的第二密封表面和插入在密封表面之间的流体输送端。 支撑结构提供流过流体传输端并经由入口孔并经由出口孔从泵室返回通过流体传送端的流体流动路径。 第一密封元件设置在第一密封表面上，第二密封元件设置在第二密封表面上。 密封元件构造成用于在泵壳体中形成密封界面，建立将泵室与流体泵壳体外部的环境隔离的静态密封件。
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公开(公告)号：US08398858B2
公开(公告)日：2013-03-19
申请号：US12529095
申请日：2008-02-26
CPC分类号： A61M1/1698 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1098 , A61M1/122 , A61M1/1678 , A61M1/267
摘要： A device is provided for transferring mass and/or exchanging energy between two media, particularly between blood and a gas/gas mixture. The device includes a chamber (2), through which the first medium flows and inside which at least one mass-permeable and/or energy-permeable hollow fiber (5), preferably a plurality of mass-permeable and/or energy-permeable hollow fibers (5), is/ are arranged. The second medium can flow through the at least one hollow fiber (5), while the first medium can flow therearound. At least one pumping element (5), which allows the first medium to be displaced from the chamber (2) and/or to be sucked into the chamber (2), is disposed in the chamber (2) of the device.
摘要翻译： 提供了用于在两个介质之间特别是在血液和气/气混合物之间传送质量和/或能量的装置。 该装置包括腔室（2），第一介质通过该腔室流过，其中至少一个质量可渗透和/或能量可渗透的中空纤维（5），优选多个质量可渗透和/或能量可渗透的中空纤维 纤维（5）。 第二介质可以流过至少一个中空纤维（5），而第一介质可以在其周围流动。 至少一个允许第一介质从腔室（2）移位和/或被吸入腔室（2）中的泵送元件（5）设置在装置的腔室（2）中。
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公开(公告)号：US08372145B2
公开(公告)日：2013-02-12
申请号：US12549561
申请日：2009-08-28
申请人： Hisham M. F. Sherif
发明人： Hisham M. F. Sherif
IPC分类号： A61M1/10
CPC分类号： A61M1/1053 , A61M1/1037 , A61M1/1044 , A61M1/1058 , A61M1/1098 , A61M1/122 , A61M1/127 , A61M2205/0283
摘要： A pulsatile, positive-displacement mechanical circulatory support pump which can be used for assistance or replacement of one or both ventricles. The pump includes a plurality of contractile elements radiating outward from an apex of a compliance chamber, the elements being incorporated in and/or in contact with at least a portion of an outer surface of the compliance chamber. These contractile elements include an electroactive dielectric elastomer or an ion exchange membrane metallic composite. Application of electric field pulses from an implantable electrical energy source such as a pacemaker will cause the contractile elements to compress and expand the compliance chamber.
摘要翻译： 脉动式，正排量机械循环支持泵，可用于辅助或更换一个或两个脑室。 泵包括多个收缩元件，其从顺应性腔室的顶点向外辐射，所述元件被结合在柔性室的外表面的至少一部分中和/或与柔性室的外表面的接触部分接触。 这些收缩元件包括电活性介电弹性体或离子交换膜金属复合物。 来自可植入电能源（例如起搏器）的电场脉冲的应用将导致收缩元件压缩和扩大顺应性室。
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公开(公告)号：US08328751B2
公开(公告)日：2012-12-11
申请号：US13107843
申请日：2011-05-13
申请人： Gad Keren , Randy Kesten
发明人： Gad Keren , Randy Kesten
IPC分类号： A61B19/00
CPC分类号： A61M27/006 , A61B17/00234 , A61B2017/00243 , A61B2017/00252 , A61F2/2412 , A61F2/2493 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/125 , A61M27/002
摘要： The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released. Preferably, the first portion comprises the left ventricle and the pressure reduced is the end diastolic pressure, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle to reduce the end diastolic pressure. Most preferably, the shunt selectively permits flow when a pressure differential between the left ventricle and another chamber of a heart above a threshold pressure, whereby shunting is prevented during left ventricular systole, or, alternatively, selectively permits flow when a pressure differential between the left ventricle and another chamber of a heart is between a lower threshold and a higher threshold, whereby shunting is again prevented during left ventricular systole. In certain embodiments a semi-passive check-valve is controlled and actuated by an external signal, either using a signal generated by an intra-corporeal electrical battery or an externally coupled energy source. In certain embodiments, the shunt has a pump with an input connected to the left ventricle, or other portion with excessive pressure, and an output connected to a volume of lower pressure. The preferred method of implanting the shunt to effect the present invention is by deploying a tubular element having two ends and a tissue affixation element disposed at each of said ends via a catheter, preferably, the fixation element is a shape retaining metallic material that returns to its original shape as part of the retention aspect of its function. In preferred embodiments of the apparatus, the tubular element is comprised of a biologically inert non-metallic material.
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公开(公告)号：US20120296358A1
公开(公告)日：2012-11-22
申请号：US13474096
申请日：2012-05-17
申请人： John Duc Nguyen , Donald Curtis , Carine Hoarau
发明人： John Duc Nguyen , Donald Curtis , Carine Hoarau
IPC分类号： A61B17/32
CPC分类号： A61B17/11 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/32002 , A61B17/32053 , A61B17/3462 , A61B2017/00243 , A61B2017/00252 , A61B2017/00526 , A61B2017/1107 , A61B2017/1125 , A61B2017/1135 , A61B2017/12004 , A61B2017/3425 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122
摘要： A coring knife can be used to make a circular incision. The coring knife includes an abutment that is inserted into an initial slit through the heart wall. The abutment can be inserted into the slit while oriented in a direction that minimizes its insertion profile. After insertion, the abutment is reoriented by turning a key so that its abutment surface faces toward a circular cutting edge of the coring knife on the other side of the heart wall. The circular incision through the heart wall is made by pressing the circular cutting edge of the coring knife against the abutment.
摘要翻译： 可以使用取心刀做圆形切口。 取芯刀包括通过心壁插入初始缝隙中的基台。 可以在沿使其插入轮廓最小化的方向定位的情况下将基台插入狭缝中。 在插入之后，通过转动钥匙来使基台重新定向，使得其邻接表面面向心壁另一侧的取心刀的圆形切割边缘。 通过心脏壁的圆形切口通过将取心刀的圆形切割边压靠在基台上而制成。
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公开(公告)号：US08070455B2
公开(公告)日：2011-12-06
申请号：US12498991
申请日：2009-07-07
申请人： Frank A. Tinker
发明人： Frank A. Tinker
CPC分类号： F04B9/042 , A61M1/1049 , A61M1/1062 , A61M1/1081 , A61M1/1098 , A61M1/12 , A61M1/127 , F04B9/047
摘要： A primary scotch yoke and a secondary scotch yoke are coupled in opposing arrangement and rigidly attached to a linearly reciprocating element. Each scotch yoke includes a rotary actuator with a cam follower and a yoke attached to the reciprocating element. Each yoke has a cam with an open gap through which the follower may be disengaged from the cam and stopped to an idle position. The follower of the secondary scotch yoke is kept idle in a position similarly disengaged from its cam. A controller detects a failure in the primary scotch yoke, disengages the cam follower of the primary yoke from its cam, and energizes the secondary scotch yoke, thereby causing its cam follower to engage its yoke and continue to provide uninterrupted motion to the reciprocating element, in particular the portable pneumatic pump driving an artificial heart.
摘要翻译： 主要的苏格兰托杆和辅助苏格兰托架以相对的布置联接并刚性地附接到线性往复元件。 每个苏格兰托架包括具有凸轮从动件的旋转致动器和附接到往复运动元件的轭。 每个轭具有带有开放间隙的凸轮，从动件可通过该凸轮与凸轮分离并停止到空转位置。 二次苏格兰托架的从动件在类似地与其凸轮脱离的位置中保持空转。 一个控制器检测到主要的苏格兰托架中的故障，使一个轭铁的凸轮从动件与其凸轮脱离接合，并且使辅助的苏格兰转动架通电，从而使其凸轮从动件与其轭架接合，并且继续向往复运动元件提供不间断的运动， 特别是便携式气动泵驱动人造心脏。
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