公开(公告)号：US20150232801A1

公开(公告)日：2015-08-20

申请号：US14421385

申请日：2013-08-20

Applicant: Chr. Hansen A/S

Inventor： Birgitte Yde ,  Tania Ivanova Georgieva ,  Anders Clausen ,  Susanne Abrahamsen

IPC: C12N1/04

CPC classification number: C12N1/04 ,  A23C9/12 ,  A23L33/135 ,  A61K9/19 ,  C12N1/20

Abstract: The present invention relates to a process for optimizing the storage stability of a freeze dried bacteria-containing product obtained from a bacteria-containing concentrate, wherein the process is carried out at a pressure which will provide a sublimation temperature which is at least 10° C. above the melting point of the frozen bacteria-containing concentrate. Further, the present invention relates to the freeze dried concentrates per se.

Abstract translation: 本发明涉及一种用于优化从含细菌浓缩物获得的含有冻干细菌的产品的储存稳定性的方法，其中该方法在提供至少10℃的升华温度的压力下进行 高于含冷冻细菌的浓缩物的熔点。 此外，本发明本身涉及冷冻干燥浓缩物本身。

公开(公告)号：US20140349331A1

公开(公告)日：2014-11-27

申请号：US14248914

申请日：2014-04-09

Applicant: Chr. Hansen A/S

Inventor： Beatrice Nielsen ,  Tina Styrishave ,  Mette Dines Cantor ,  Patrick Derkx ,  Jonna Nielsen ,  Robert Lantz

IPC: C12Q1/02

CPC classification number: C12Q1/02 ,  A23K10/18 ,  A23K20/163 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  G01N2333/32

Abstract: Described are methods for assaying whether a Bacillus composition comprising at least one Bacillus strain is capable of increasing the amount of available sugar from animal feed comprising non-starch polysaccharides (NSP). Also described are methods for increasing the amount of available sugar from animal feed comprising non-starch polysaccharides (NSP), comprising adding to the animal feed a Bacillus composition comprising at least one Bacillus strain, which compositions produces 120 hexose equivalents (μmol/ml) or more when measured by the method described herein. Also described are animal feeds comprising 14% (w/w) or more of non-starch polysaccharides (NSP) if the animal feed is for a piglet, lactating sow, broiler or layer or 19% (w/w) or more of non-starch polysaccharides (NSP) if the animal feed is for a grower-finisher pig or gestating sow, and a Bacillus composition comprising at least one Bacillus strain, as well as methods and uses relating thereto.

Abstract translation: 描述了用于测定包含至少一种芽孢杆菌菌株的芽孢杆菌组合物是否能够增加来自包含非淀粉多糖（NSP）的动物饲料的可用糖的量的方法。 还描述了用于增加来自包含非淀粉多糖（NSP）的动物饲料的可用糖的量的方法，其包括向动物饲料中加入包含至少一种芽孢杆菌菌株的芽孢杆菌组合物，该组合物产生120己糖当量（μmol/ ml） 或更多，当通过本文所述的方法测量时。 还描述了如果动物饲料用于仔猪，哺乳母猪，肉鸡或多层或19％（w / w）以上的非淀粉多糖（NSP），则含有14％（w / w） 淀粉多糖（NSP），如果动物饲料用于种植者育种猪或妊娠母猪，以及包含至少一种芽孢杆菌菌株的芽孢杆菌组合物，以及与其相关的方法和用途。

公开(公告)号：US20140348978A1

公开(公告)日：2014-11-27

申请号：US14366552

申请日：2012-12-21

Applicant: Chr. Hansen A/S ,  University of Copenhagen

Inventor： Kirsten Kastberg Moeller ,  Fergal Rattray ,  Erik Hoeier ,  Yiva Ardoe

IPC: A23C19/032 ,  C12R1/225

CPC classification number: A23C19/0323 ,  A23C19/04 ,  A23C19/064 ,  A23C19/072 ,  A23L27/00 ,  A23L27/40 ,  A23L33/00 ,  A23Y2220/39 ,  A23Y2240/41 ,  C12N9/88 ,  C12R1/225

Abstract: The present invention relates to a method for producing cheese with good flavour, especially low-salt cheese by using a lactic acid bacteria (LAB) starter culture which is glutamate decarboxylation (GAD) negative. The method may additionally involve inoculating the milk substrate with a GAD-negative Lb. helveticus strain having a high lytic and peptidolytic activity, which further releases glutamate into the milk Additional application of camel chymosin reduces bitterness.

Abstract translation: 本发明涉及通过使用谷氨酸脱羧（GAD）阴性的乳酸菌（LAB）起始培养物，生产具有良好风味的干酪，特别是低盐干酪的方法。 该方法还可以包括用GAD阴性Lb接种乳底物。 具有高裂解活性和解肽活性的螺旋藻菌株，其进一步将谷氨酸释放到乳中。另外施用骆驼凝乳酶可减少苦味。

公开(公告)号：US20140271989A1

公开(公告)日：2014-09-18

申请号：US14355807

申请日：2012-11-05

Applicant: Chr. Hansen A/S

Inventor： Sofie Saerens ,  Jan Hendrik Swiegers

IPC: A23G1/02 ,  A23G1/30

CPC classification number: A23G1/30 ,  A23G1/002 ,  A23G1/02 ,  A23G1/42 ,  C12R1/84

Abstract: Described are Pichia kluyveri yeast strains with advantageous properties useful in cacao fermentation processes, and related methods and products, including fermented cocoa beans having a ratio of isobutyl acetate/isobutanol higher than 1 and/or a ratio of isoamyl acetate/isoamyl alcohol higher than 0.005, and cocoa-based products prepared therefrom, as well as methods for the fermentation of cocoa beans comprising using at least one Pichia kluyveri yeast strain, fermented cocoa beans obtainable thereby, and cocoa-based products prepared therefrom and obtainable thereby.

Abstract translation: 描述了在可可发酵方法中有利的性质的毕赤酵母酵母菌株，以及相关方法和产品，包括具有高于1的乙酸异丁酯/异丁醇的比例和/或高于0.005的异戊醇的比例的发酵可可豆 以及由其制备的可可基产品，以及发酵可可豆的方法，其包括使用至少一种毕赤酵母酵母菌株，由此获得的发酵可可豆以及由此制备的可可基产物。

公开(公告)号：US20140072670A1

公开(公告)日：2014-03-13

申请号：US14017029

申请日：2013-09-03

Applicant: Eidgenossische Technische Hochschule Zurich ,  CHR. HANSEN A/S

Inventor： Stefan KAPPELER ,  Zakaria Farah ,  Johannes Maarten Van den Brink ,  Henrik Rahbek-Nielsen ,  Peter Budtz

IPC: A23C19/04

CPC classification number: A23C19/043 ,  C12N9/6483 ,  C12Y304/23004

Abstract: A method of recombinantly producing a non-bovine pre-prochymosin, prochymosin or chymosin derived from ruminant species including deer species, buffalo species, antelope species, giraffe species, ovine species and caprine species; Camefidae species such as Came/us dromedarius; porcine species; or Equ;dae species. The recombinant enzymes are used in milk coagulating compositions in cheese manufacturing based on cow's milk and milk from any animal species which are used in cheese manufacturing including camel's milk.

Abstract translation: 一种重组产生源自鹿类，水牛种，羚羊种，长颈鹿物种，羊种和山羊种的反刍动物物种的非牛前凝乳酶原，凝乳酶原或凝乳酶的方法; Camefidae种类，如Came / us dromedarius; 猪种; 或Equ。dae物种。 重组酶用于奶酪制造中的牛奶凝固组合物，其基于来自用于奶酪制造的任何动物物种的牛奶和牛奶，包括骆驼乳。

公开(公告)号：US20130336942A1

公开(公告)日：2013-12-19

申请号：US13900243

申请日：2013-05-22

Applicant: CHR-HANSEN A/S

Inventor： Thomas Dyrmann Leser ,  Thomas GUNNARSSON ,  Jens KILDSGAARD ,  Janni Wandahl PEDERSEN ,  Bénédicte FLAMBARD

IPC: A61K35/74 ,  A61K45/06

CPC classification number: A61K35/742 ,  A61K8/99 ,  A61K31/702 ,  A61K35/747 ,  A61K45/06 ,  A61Q19/06 ,  C12R1/225

Abstract: The use of probiotic bacteria that modulate expression of a number of satiety markers in the intestine and reduces fat deposition to promote an optimal body weight of a mammal is described. The invention further relates to a composition comprising such a probiotic strain of bacteria and/or a fraction of said strain and/or metabolite of said strain for the preparation of a composition for administration to a mammal for promoting an optimal body weight of a mammal.

Abstract translation: 描述了使用调节许多饱腹感标记物在肠中的表达并减少脂肪沉积以促进哺乳动物的最佳体重的益生菌。 本发明还涉及一种组合物，其包含这样的益生菌菌株和/或所述菌株的所述菌株和/或代谢物的级分，用于制备用于给哺乳动物施用哺乳动物的最佳体重的组合物。

公开(公告)号：US20130071907A1

公开(公告)日：2013-03-21

申请号：US13676879

申请日：2012-11-14

Applicant: Chr. Hansen A/S

Inventor： Inge KNAP ,  Ane KNARREBORG ,  Thomas Dyrmann LESER ,  Bente LUND

IPC: C12N1/20 ,  C40B30/08

CPC classification number: C12N1/20 ,  A23K10/18 ,  A23K50/30 ,  A23K50/75 ,  A23K50/80 ,  A23L27/203 ,  C12N15/01 ,  C12R1/125

Abstract: A bacillus composition characterized by fast germination and outgrowth in bile salts (simulated gut environment) and by high-level secretion of phytase. The bacillus composition may be used as supplement in animal feed where it has a probiotic (health promoting) effect and increases the digestion and availability of nutrients from animal feeds.

Abstract translation: 一种芽孢杆菌组合物，其特征在于胆汁盐（模拟肠道环境）的快速发芽和生长以及植酸酶的高水平分泌。 芽孢杆菌组合物可以用作动物饲料中的补充物，其中它具有益生菌（促进健康）作用并且增加动物饲料中营养物质的消化和可利用性。

公开(公告)号：US20030228680A1

公开(公告)日：2003-12-11

申请号：US10413533

申请日：2003-04-15

Applicant: CHR. HANSEN A/S

Inventor： Boerge Kringelum ,  Lene Kragelund

IPC: C12N001/20 ,  C12N001/16 ,  C12N001/18

CPC classification number: A23C19/0323 ,  C12N1/04 ,  C12N1/20 ,  C12N1/38

Abstract: Liquid microbial starter culture that retains its initial metabolic activity during storage for extended periods of time. Such liquid starter cultures are useful in the manufacturing of food and feed products. Starter cultures of the invention include culture of lactic acid bacteria, e.g. Lactococcus species.

Abstract translation: 液体微生物发酵剂培养物在长时间保存期间保持其初始代谢活性。 这种液体起始培养物可用于制造食品和饲料产品。 本发明的起始培养物包括乳酸菌的培养，例如， 乳球菌属。

公开(公告)号：US20250163364A1

公开(公告)日：2025-05-22

申请号：US18842354

申请日：2023-03-03

Applicant: Chr. Hansen A/S

Inventor： Hans BISGAARD-FRANTZEN ,  Lars CHRISTENSEN ,  Surender Kumar DHAYAL ,  Francesco Cristino Falco ,  Neda FARGHIPARAPARI ,  Anisha GOEL ,  Marie Penderup JENSEN ,  Jakub KOVACS ,  Hamed Nasri LARI ,  Henrik Moellgaard ,  Robin Toponen ORTHAGEN ,  Milica RANDELOVIC ,  Catarina SEITA ,  Kim Ib SOERENSEN ,  Tina Malling THORSEN ,  Miguel TOSCANO ,  Jakob WORM

IPC: C12N1/20 ,  C12N1/04 ,  C12N9/08 ,  C12R1/46

Abstract: The present invention relates to microbial starter cultures. More specifically, a method for preparing a microbial culture such as a lactic acid bacteria (LAB) starter culture wherein at least one microbial strain such as a lactic acid bacteria and at least one hemoprotein is inoculated in a culture medium.

公开(公告)号：US20250160351A1

公开(公告)日：2025-05-22

申请号：US19027254

申请日：2025-01-17

Applicant: Chr. Hansen A/S

Inventor： Sonja BLOCH ,  Gaelle Lettier BUCHHORN

IPC: A23C9/123 ,  A23C17/02 ,  C12R1/46

Abstract: The present invention relates to a composition for producing a fermented milk product comprising (i) at least one Streptococcus thermophilus (St) strain, wherein the St strain is galactose-fermenting, wherein the strain carries a mutation in the DNA sequence of the gick gene encoding a glucokinase protein, wherein the mutation inactivates the glucokinase protein or has a negative effect on expression of the gene, and (ii) at least one Lactobacillus delbrueckii subsp. bulgaricus (Lb) strain, wherein the Lb strain is lactose-deficient and capable of metabolizing a non-lactose carbohydrate.