Abstract:
It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia.(S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.
Abstract:
The present invention provides a novel corneal thickness modulating agent. The present invention pertains to a corneal thickness modulating agent containing 1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine or a salt thereof or a solvate thereof.
Abstract:
It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia.(S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.
Abstract:
A measurement optical system (30) is provided which causes measurement light split by a beam splitter (20) to be incident to an object, and a reference optical system (40) is provided which causes reference light split by the beam splitter to be incident to a reference mirror (49). A tomographic image of the object is formed on the basis of interference light generated by superposition of the measurement light reflected at the object to return and the reference light reflected at the reference object to return. Optical components such as lenses and mirrors that constitute the measurement optical system and reference optical system correspond to each other, and the wavelength dispersion characteristics of the optical components in the correspondence relationship are identical or equivalent.
Abstract:
[Problem] To make it possible to prevent vibrations or the like from causing focus or zoom slippage or the like in a lens that is mounted to a camera body that is used in a fixed location outdoors for many years for security purposes or is used inside a building that is subject to a variety of variations, such as a camera that is used for quality-checking purposes or the like at a production site in a factory.[Solution] The lens barrel (1) in this invention has the following: a fixed tube section (10) that is mounted to a camera body (B); a movable tube section (20) that is movably screwed to the fixed tube section (10); and a nut member (12) that, screwed to the movable tube section (20), is energized towards top end (10b) of the fixed tube section (10). The nut member (12) acts as a double nut, making it possible to inhibit rotation of the fixed tube section (10) and the movable tube section (20) relative to each other, preventing focus or zoom slippage or the like.
Abstract:
A hand joint supporter which can reduce the load on hand joints includes a first anchor section for tightening the wearer's forearm with a tubular knitted fabric, a second anchor section for tightening the palm and back of the wearer's hand with the fabric and a hole anchor section formed as a roughly circular through-hole in the vicinity of the second anchor section. A supporting section extends lengthwise in the fabric across the part covering the caprometacarpal joint and is joined to the first anchor section and the hole anchor section so as to support the wearer's hand joints. Stretch resistance, in the circumferential direction of the fabric of the first anchor part is larger than that of a base fabric section, and stretch resistance, in the length width direction of the fabric, of the supporting section is larger than that of the base fabric section.
Abstract:
The present invention provides a method for the prevention and treatment of complications after cataract surgery such as secondary cataract and anterior capsule contraction that occur after cataract operation.The present invention relates to a preventive/therapeutic method comprising administering to a subject a medicine containing 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline (Ripasudil) or a salt thereof, or a solvate thereof as an active ingredient.
Abstract:
A regeneration promoter for regenerating tissue with the use of somatic stem cells is provided. Also provided are a cell fusion promoter comprising ATP or its metabolite which is safely usable in vivo, a method of producing fused cells in the presence of ATP or its metabolite and a related pharmaceutical composition for regenerating or improving the function of a tissue or an organ in a subject suffering from dysfunction or hypofunction due to injury or denaturation.
Abstract:
An intraocular lens wherein an outer edge of a support part has a curved concave shape at a base thereof and extends therefrom toward a tip thereof with a curved convex shape having a radius of curvature of 5.25 to 7.50 mm. In a region where a Y coordinate of an orthogonal coordinate system is 1.0 mm or greater, an origin of the coordinate system being a geometric center of an optical part, an inner edge of the support part is positioned between shapes obtained by offsetting the outer edge of the support part by 0.2 mm and by 1.0 mm towards the X-axis origin. The tip of the support part is positioned in a region where the Y coordinate is greater than a radius of the optical part, outside a circle with a radius of 5.0 mm centered on the origin.
Abstract:
The present invention provides a technique that makes it possible, when inserting an intraocular lens into an eye by pushing a plunger, to insert a support positioned on the rear side of the pushing direction of the lens body of the intraocular lens integrally with the lens body and to stabilize the shape of the support after insertion. A slanted part (61f) slanted so as to be higher from the front side to the rear side of a plunger (60) or from the left side to the right side of a plunger (60) is provided at the tip (61d) of a plunger (60). A wall part (61g) formed in a plane perpendicular to the pushing direction of the plunger (60) is provided on the rear side of the slanted part (61f). A plate-shaped protrusion (61e) that protrudes forward from the slanted part (61f) so that part of the lens body can be mounted is provided on the lower side of the slanted part (61f).