公开(公告)号：US20180207235A1

公开(公告)日：2018-07-26

申请号：US15745432

申请日：2016-07-18

Applicant: THE UNIVERSITY OF QUEENSLAND ,  MONASH UNIVERSITY

Inventor： Glenn Frederick KING ,  Lachlan Douglas RASH ,  Irene CHASSAGNON ,  Sandy Steffany PINEDA GONZALEZ ,  Robert Edward WIDDOP ,  Claudia Ann IRELAND

IPC: A61K38/17 ,  A61K9/00 ,  A61P25/28 ,  A61P25/08 ,  A61P9/10 ,  A61P9/14

CPC classification number: A61K38/1767 ,  A61K9/0019 ,  A61K9/0043 ,  A61K9/0085 ,  A61K38/00 ,  A61P9/10 ,  A61P9/14 ,  A61P25/08 ,  A61P25/28 ,  C07K14/43518 ,  C07K2319/23 ,  C07K2319/24 ,  C07K2319/50

Abstract: The invention relates to disulfide-rich peptides derived from spider venom and their use, particularly as neuroprotective agents. The invention also relates to nucleic acid molecules encoding the peptides as well as constructs and host cells comprising those nucleic acid molecules.

公开(公告)号：US20180172711A1

公开(公告)日：2018-06-21

申请号：US15739427

申请日：2016-06-17

Applicant: MONASH UNIVERSITY

Inventor： Junfei TIAN ,  Wei SHEN ,  Gil GARNIER ,  David BASHFORD ,  Heather MCLIESH

IPC: G01N33/80 ,  G01N33/52 ,  G01N33/543 ,  G01N21/84

CPC classification number: G01N33/80 ,  G01N21/8483 ,  G01N33/525 ,  G01N33/54386 ,  G01N33/558 ,  G01N2021/7766 ,  G01N2021/7793 ,  G01N2021/7796

Abstract: A diagnostic device for analysing properties of an analyte in a sample liquid including: a distribution zone having at least two hydrophilic layers placed one on top of the other, wherein one layer is a top layer (12) and the other is a bottom layer (13); and a detection zone located under the distribution zone, the detection zone having a detection layer (14), wherein: the top layer has one or more openings (15) through which the sample liquid is introduced into the device; the bottom layer having one or more openings (16) connecting the distribution zone to the detection zone; the bottom layer also having a means by which the sample liquid is distributed from the top layer's opening to the detection layer through the bottom layer's opening; and a visual indication results on the detection layer when the sample liquid comes into contact with the detection layer.

公开(公告)号：US20180090024A1

公开(公告)日：2018-03-29

申请号：US15563423

申请日：2015-03-31

Applicant: TALI Health Pty Ltd ,  Monash University

Inventor： Andrew Somers ,  Grace Lethlean ,  Hannah Kirk ,  Kim Cornish

IPC: G09B7/02 ,  A61B5/16 ,  A63F13/44 ,  A63F13/50

CPC classification number: G09B7/02 ,  A61B5/168 ,  A63F13/00 ,  A63F13/44 ,  A63F13/50

Abstract: A process for cognitive assessment and training, the process being executed by at least one processor of a computing system and including the steps of: receiving interaction data representing interactions between an application executing on an electronic device and an individual interacting with the executing application; processing the interaction data to generate performance data representing quantitative measures of the performance of the individual with respect to the executing application; and processing the performance data for the individual to generate cognitive assessment data indicative of at least one attention-related ability of the individual.

公开(公告)号：US09904824B2

公开(公告)日：2018-02-27

申请号：US15331140

申请日：2016-10-21

Applicant: Monash University

Inventor： Nemai Chandra Karmakar ,  Mohammad Zomorrodi

IPC: G06K7/10 ,  G01S3/00 ,  G06K19/067 ,  H01Q1/00 ,  H04B7/00

CPC classification number: G06K7/10356 ,  G01S3/00 ,  G01S3/08 ,  G01S13/74 ,  G06K7/10316 ,  G06K7/10366 ,  G06K19/0672 ,  H01Q1/00 ,  H01Q1/2216 ,  H01Q1/2225 ,  H01Q15/0006 ,  H04B5/0062 ,  H04B7/00 ,  H04B7/04 ,  H04B7/10

Abstract: A mm-wave RFID tag interrogation apparatus includes multiple transmitting antennas, and multiple receiving antennas. The transmitting and receiving antennas are spatially distributed and oriented in orthogonal polarization states. A transmitter is coupled to the transmitting antennas, and transmits a corresponding multiple number of separable mm-wave signals. A receiver coupled to the receiving antennas is configured to extract separable components of received mm-wave signals. A processing unit processes the extracted signal components using a synthetic aperture algorithm. An RFID tag, readable by the interrogation apparatus, includes meander-line conductive elements arranged to encode information spatially on a substrate.

公开(公告)号：US20170259610A1

公开(公告)日：2017-09-14

申请号：US15453680

申请日：2017-03-08

Applicant: MONASH UNIVERSITY

Inventor： Wenlong CHENG ,  Kae Jye SI

IPC: B42D25/378 ,  G07D7/12 ,  C09D11/03 ,  B42D25/29 ,  C09D125/06 ,  G07D7/00 ,  G07D7/20

CPC classification number: B42D25/378 ,  B42D25/29 ,  B82Y20/00 ,  B82Y40/00 ,  C09D11/03 ,  G07D7/003 ,  G07D7/12 ,  G07D7/2016 ,  G09F3/00 ,  Y10S977/943

Abstract: Ultrathin plasmene nanosheets are demonstrated as a new class of flexible surface enhanced Raman scattering (SERS) substrate capable of conformal attachment and sensitive and reproducible detection of chemicals on topologically complex surfaces. Engineering building block morphologies allows for fine-tuning of the SERS performance. In a preferred application the plasmene nanosheets are demonstrated as the next generation plasmonic and/or SERS coded labels, such as for example, anti-counterfeit security label for banknotes. Engineering the morphologies of plasmene-constituent nanoparticles and varying of SERS molecular labels offer virtually unlimited coding capacities.

公开(公告)号：US20170079770A1

公开(公告)日：2017-03-23

申请号：US15124402

申请日：2015-03-23

Applicant: Monash University

Inventor： Wai Ho LI

IPC: A61F2/14 ,  A61N1/36 ,  G06T11/60 ,  G06K9/00

CPC classification number: A61F2/14 ,  A61N1/36046 ,  G06K9/00671 ,  G06T11/00 ,  G06T11/60

Abstract: A visual image processing method is based on received spatial field information (302) from a spatial field sensor (116). A data store (804) is accessed, which contains a sensor map data structure (206) comprising a set of predefined regions (208) within a spatial field corresponding with the information received via the sensor input. Each predefined region is associated in the data structure with one or more of a set of stimuli (204) applicable to a biological visual system, and each stimulus corresponds with a visual percept (210). The spatial field information associated with each region is processed to generate stimulus control information which is applied to select, from within the sensor map data structure, stimuli from the set of stimuli for application to the biological visual system. Output stimulus signals (310) are generated, which are suitable for application to the biological visual system based upon the selected stimuli. Flexible mappings are thus provided between visual percepts, stimuli which may be applied (e.g. via a prosthetic implant) in order to generate the percepts, and associations between those stimuli and regions of the spatial field corresponding with the visual percepts.

公开(公告)号：US09576354B2

公开(公告)日：2017-02-21

申请号：US14350383

申请日：2012-10-10

Applicant: MONASH UNIVERSITY

Inventor： Andreas Fouras ,  Stephen Dubsky ,  Jordan Thurgood

IPC: G06T7/00 ,  G06T19/00 ,  A61B6/03 ,  A61B6/00

CPC classification number: G06T7/0012 ,  A61B6/032 ,  A61B6/481 ,  A61B6/486 ,  A61B6/50 ,  A61B6/503 ,  A61B6/507 ,  A61B6/508 ,  A61B6/5211 ,  A61B6/5288 ,  G06T19/00 ,  G06T2210/41

Abstract: The present invention relates to imaging of a human or animal heart, particularly imaging of movement of the heart and can be used for imaging function and form in a wide range of research, medical, veterinary and industrial applications. In particular, the present invention provides a method and apparatus for imaging a subject heart, the method including the steps of (1) recording at least one in vivo image of a lung of the subject in one or more regions; (2) applying said at least one in vivo image to a 2D or 3D heart model; and (3) reconstructing a 2D or 3D image field of the subject heart.

Abstract translation: 本发明涉及人或动物心脏的成像，特别是心脏移动的成像，并且可用于广泛的研究，医学，兽医和工业应用中的成像功能和形式。 特别地，本发明提供了一种用于对主体心脏进行成像的方法和装置，所述方法包括以下步骤：（1）在一个或多个区域中记录受试者的肺的至少一个体内图像; （2）将所述至少一个体内图像应用于2D或3D心脏模型; 和（3）重建主体心脏的2D或3D图像场。

公开(公告)号：US20170008976A1

公开(公告)日：2017-01-12

申请号：US15116487

申请日：2015-02-04

Applicant: MONASH UNIVERSITY ,  MEMORIAL SLOAN-KETTERING CANCER CENTRE ,  LUDWIG INSTITUTE FOR CANCER RESEARCH LTD

Inventor： Martin LACKMANN ,  Peter W. JANES ,  Lakmali Atapattu MUDIYANSELAGE ,  Andrew M. SCOTT ,  Dimitar B. NIKOLOV ,  Nayanendu SAHA

IPC: C07K16/40 ,  G01N33/574 ,  C07K16/30

CPC classification number: C07K16/40 ,  A61K31/4745 ,  A61K39/39558 ,  A61K2039/505 ,  C07K16/30 ,  C07K16/3023 ,  C07K16/3038 ,  C07K16/3053 ,  C07K16/3069 ,  C07K2299/00 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/565 ,  C07K2317/76 ,  C12Y302/00 ,  G01N33/573 ,  G01N33/574 ,  G01N33/57484 ,  G01N33/57492 ,  G01N2333/96486 ,  A61K2300/00

Abstract: Expression of proteolytically active, high molecular weight ADAM protease is relatively increased in tumour cells that also express the putative tumour stem cell marker CD133. An antibody or antibody fragment such as 8C7 monoclonal antibody may be used to selectively bind to proteolytically active, high molecular weight ADAM10 protease to thereby detect tumour cells and also as a therapeutic agent for treating cancers, tumours and other malignancies inclusive of leukemia, lymphoma, lung cancer, colon cancer, adenoma, neuroblastoma, brain tumour, renal tumour, prostate cancer, sarcoma and/or melanoma.

Abstract translation: 蛋白水解活性的高分子量ADAM蛋白酶的表达在也表达推定的肿瘤干细胞标志物CD133的肿瘤细胞中相对增加。 抗体或抗体片段如8C7单克隆抗体可用于选择性结合蛋白水解活性的高分子量ADAM10蛋白酶，从而检测肿瘤细胞，并且还可用作治疗癌症，肿瘤和其它恶性肿瘤的治疗剂，包括白血病，淋巴瘤， 肺癌，结肠癌，腺瘤，神经母细胞瘤，脑肿瘤，肾肿瘤，前列腺癌，肉瘤和/或黑素瘤。

公开(公告)号：US09533282B2

公开(公告)日：2017-01-03

申请号：US14416405

申请日：2013-07-26

Applicant: Commonwealth Scientific and Industrial Research Organisation ,  Monash University

Inventor： Bradley Ladewig ,  Richelle Lyndon ,  Matthew Hill

IPC: B01D53/02 ,  B01J20/28 ,  B01J20/34 ,  B01J20/22 ,  B01D53/04

CPC classification number: B01J20/3441 ,  B01D53/02 ,  B01D53/04 ,  B01D2253/204 ,  B01D2257/504 ,  B01D2259/40083 ,  B01J20/226 ,  B01J20/28011 ,  B01J20/3425 ,  B01J20/3433 ,  Y02C10/08

Abstract: A process for the separation of a gas from a gas stream using metal organic framework that is reversibly switchable between a first conformation that allows the first gas species to be captured in the metal organic framework, and a second conformation that allows the release of the captured first gas species, using light as the switching stimulus. The metal organic framework may comprise a metal and one or more ligands, in which the ligands contain an isomerizable group within the molecular chain that forms a link between adjacent metal atoms in the metal organic framework.

Abstract translation: 一种使用金属有机骨架从气流中分离出气体的方法，所述框架可在允许第一气体种类被捕获在金属有机骨架中的第一构象之间可逆地切换;以及第二构型，其允许所捕获的 第一种气体，使用光作为切换刺激。 金属有机骨架可以包含金属和一种或多种配体，其中配体在分子链内包含在金属有机骨架中相邻的金属原子之间形成连接的可异构化基团。

公开(公告)号：US20160145332A1

公开(公告)日：2016-05-26

申请号：US14392256

申请日：2014-06-27

Applicant: MONASH UNIVERSITY

Inventor： Charles Reay Mackay ,  Di Yu

IPC: C07K16/24 ,  A61K45/06 ,  A61K39/395

CPC classification number: C07K16/244 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/74 ,  C07K2317/75 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present disclosure provides proteins comprising antigen binding sites of antibodies that bind to interleukin-21 (IL-21) and uses thereof, e.g., in therapy.

Abstract translation: 本公开提供了包含结合白细胞介素-21（IL-21）的抗体的抗原结合位点及其用途（例如在治疗中）的蛋白质。