公开(公告)号：US20180306802A1

公开(公告)日：2018-10-25

申请号：US15881489

申请日：2018-01-26

申请人： Lightship Medical Limited

发明人： Barry Colin Crane ,  William Paterson ,  Nicholas Paul Barwell ,  Peter Edgley

IPC分类号： G01N33/66 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/145 ,  G01N21/64 ,  G01N21/77 ,  G01N27/327

CPC分类号： G01N33/66 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/7703 ,  G01N27/3271 ,  G01N2021/6432 ,  G01N2021/6434 ,  G01N2021/6441 ,  G01N2021/6484 ,  G01N2021/772 ,  G01N2021/773 ,  G01N2021/7786 ,  G01N2021/7793

摘要： A method of quantifying the amount of glucose in a sample is provided herein that may further comprise an interferent such as mannitol. At least two measurements are obtained using measurement methods that differ in their sensitivity to the amount of interferent in the sample, thus enabling the results to be compared to determine whether any interferent is present in the sample. A glucose sensor for carrying out a method described herein is also provided

公开(公告)号：US20180266964A1

公开(公告)日：2018-09-20

申请号：US15764954

申请日：2016-10-07

申请人： Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO

发明人： Bart Michiel de Boer ,  Paul Louis Maria Joseph van Neer ,  Peter Johan Harmsma

IPC分类号： G01N21/77

CPC分类号： G01N21/7746 ,  G01N2021/7793 ,  G01N2201/0873 ,  G02B6/12004 ,  G02B2006/12109 ,  G02B2006/12138

摘要： The present disclosure concerns a method and apparatus for measuring a sensor (10) comprising multiple optical resonators (11,12) optically connected to a single optical output interface (16). The optical resonators (11,12) are interrogated with a light input signal (Si). A light output signal (So) is measured from the optic al output interface (16) to determine a combined spectral response (Sa) covering a wavelength range (W) including a plurality of resonance peaks (λ1,i, λ2,j) for each of the optical resonators (11,12). A Fourier transform spectrum (FT) of the combined spectral response (Sa) is calculated and a harmonic series of periodic peaks (n·f1) is identified in the Fourier transform spectrum (FT). The harmonic series of periodic peaks is filtered to obtain a filtered Fourier transform spectrum (FT1) and a sensor signal is calculated (X1) based on the filtered Fourier transform spectrum (FT1).

公开(公告)号：US20170343471A1

公开(公告)日：2017-11-30

申请号：US15607475

申请日：2017-05-27

申请人： The Government of the United States of America, as represented by the Secretary of the Navy

发明人： Anthony P. Malanoski ,  Brandy J. White ,  Jeffrey S. Erickson ,  David A. Stenger

IPC分类号： G01N21/31 ,  G01N21/55 ,  G06F3/147 ,  G06F17/18

CPC分类号： G01N21/31 ,  G01N21/55 ,  G01N21/78 ,  G01N2021/7793 ,  G06F3/147 ,  G06F17/18

摘要： Systems and methods are provided for identification of a detection event relevant in applications focused on real-time or near real-time reporting in a continuous monitoring application. A controller collects data from a plurality of sensors and compares recent data to background data to determine whether an event has occurred. A system in accordance with an embodiment of the present disclosure is considered to have detected an event of interest when at least a specified minimum number of sensors report a detection event at the same time.

公开(公告)号：US09791377B2

公开(公告)日：2017-10-17

申请号：US15031866

申请日：2014-10-15

申请人： TecSense Gmbh

发明人： Volker Ribitsch ,  Johannes Krottmaier

IPC分类号： G01N21/77 ,  G01J3/02 ,  G01J3/44 ,  G01N21/64

CPC分类号： G01N21/77 ,  G01J3/0202 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/4406 ,  G01N21/6428 ,  G01N21/643 ,  G01N21/645 ,  G01N21/7703 ,  G01N2021/6419 ,  G01N2021/6432 ,  G01N2021/6441 ,  G01N2021/6484 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2021/7796 ,  G01N2201/064

摘要： An optochemical sensor comprises a measuring element excitable by the light of an excitation light source and in contact with a medium to be measured, and a measuring arrangement including at least one excitation light source and a detector as well as a hood separating the measuring arrangement from the measuring element, wherein the excitation light source and the detector are fixed to a base plate arranged in parallel with the measuring element, the hood, the excitation light source and the detector are separated from one another by at least a portion of the material thickness of the hood, and light from the excitation light source through an optical waveguide impinges on the measuring element at such an angle that fluorescence light emitted by the measuring element impinges perpendicularly on the detector.

公开(公告)号：US20170212055A1

公开(公告)日：2017-07-27

申请号：US15412475

申请日：2017-01-23

申请人： Osmo Systems, Inc.

发明人： Zachary Stein ,  James Regulinski ,  Paul Holowko

IPC分类号： G01N21/77 ,  G01N21/85

CPC分类号： G01N21/77 ,  G01N21/274 ,  G01N21/8507 ,  G01N2021/755 ,  G01N2021/7763 ,  G01N2021/7793 ,  G01N2201/0218

摘要： The disclosure describes various embodiments that utilize optical sensor to characterize attributes of a liquid. Some sensor configuration continue to function properly even after scaling begins to reduce the visibility of photochemical sensors that measure the attributes of the liquid. This allows significantly longer continuous operating periods and lower maintenance costs.

公开(公告)号：US09606116B2

公开(公告)日：2017-03-28

申请号：US14706159

申请日：2015-05-07

申请人： LIA Diagnostics, Inc.

发明人： Bethany Ann Edwards ,  Frances Melina DiMare

IPC分类号： G01N21/75 ,  G01N33/543 ,  G01N33/548 ,  G01N21/78 ,  B01L3/00 ,  G01N21/77

CPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/14507 ,  A61B5/20 ,  A61B5/207 ,  A61B10/007 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/505 ,  B01L2300/0825 ,  B01L2300/0861 ,  B01L2300/123 ,  B01L2300/126 ,  B01L2400/0406 ,  G01N21/78 ,  G01N33/493 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/548 ,  G01N33/558 ,  G01N33/76 ,  G01N2021/7793

摘要： A flexible, integrated, urine-based diagnostic device designed such that one or more diagnostic channels are integrated into the body of the device. Each diagnostic channel is designed to contain an immunoassay to detect the presence of a selected analyte so that the device can return a visible readout indicating the presence of the analyte. The flexibility of the device aids the user in the sample collection process.

公开(公告)号：US20170074801A1

公开(公告)日：2017-03-16

申请号：US15269912

申请日：2016-09-19

申请人： FLIR Detection, Inc.

发明人： Brian Dwayne O'Dell ,  Marcus LaGrone ,  Martin Leuschen

IPC分类号： G01N21/78 ,  G01N33/00

CPC分类号： G01N21/783 ,  G01N21/77 ,  G01N33/0057 ,  G01N2021/7763 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2201/024

摘要： The invention provides for a multiple analyte detector that is capable of detecting and identifying explosive, chemical or biological substances having multiple analytes with a single system having multiple reporters. The reporters include fluorescent polymers, conducting polymers, metal oxide elements; electrochemical cells, etc. The reporters may be combinations of other reporters that are optimized for broadband detection.

摘要翻译： 本发明提供了一种多分析物检测器，其能够利用具有多个记录器的单个系统来检测和识别具有多个分析物的爆炸性，化学或生物物质。 记者包括荧光聚合物，导电聚合物，金属氧化物元素; 电化学电池等。记者可以是针对宽带检测而优化的其他记者的组合。

公开(公告)号：US09557329B2

公开(公告)日：2017-01-31

申请号：US14541093

申请日：2014-11-13

申请人： Assurance LLC

发明人： Jin Po Lee

IPC分类号： G01N33/558 ,  G01N33/543 ,  G01N21/78 ,  G01N33/74 ,  G01N21/64 ,  G01N21/77

CPC分类号： G01N33/54373 ,  G01N21/78 ,  G01N33/54366 ,  G01N33/558 ,  G01N33/57434 ,  G01N33/57473 ,  G01N33/74 ,  G01N33/78 ,  G01N2021/6439 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2021/7796 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/805 ,  Y10S436/81 ,  Y10S436/811 ,  Y10S436/813 ,  Y10S436/814 ,  Y10S436/818

摘要： The present invention related to a quantitative assay device and a method for the determination of an analyte, based on a test strip, which contains a porous test membrane allowing for capillary flow of the analyte and complexes of the analyte, a porous upstream membrane in fluid connection with the test membrane and a porous downstream membrane in fluid connection with the test membrane, wherein the test membrane contains two bands having deposited on there high and low concentrations of different calibrator agents and a test band capable of reacting with conjugated analyte complexes giving rise to a measurable signal.

摘要翻译： 本发明涉及一种定量测定装置和一种基于测试条测定分析物的方法，该测试条包含允许分析物和分析物复合物毛细管流动的多孔测试膜，流体中的多孔上游膜 与测试膜的连接和与测试膜流体连接的多孔下游膜，其中测试膜包含沉积有高浓度和低浓度的不同校准剂的两个带和能够与共轭分析物复合物反应的测试带 到可测量的信号。

公开(公告)号：US20160327553A1

公开(公告)日：2016-11-10

申请号：US14706159

申请日：2015-05-07

申请人： Bethany Ann Edwards ,  Francess Melina DiMare

发明人： Bethany Ann Edwards ,  Francess Melina DiMare

IPC分类号： G01N33/543 ,  G01N21/78 ,  B01L3/00 ,  G01N33/548

CPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/14507 ,  A61B5/20 ,  A61B5/207 ,  A61B10/007 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/505 ,  B01L2300/0825 ,  B01L2300/0861 ,  B01L2300/123 ,  B01L2300/126 ,  B01L2400/0406 ,  G01N21/78 ,  G01N33/493 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/548 ,  G01N33/558 ,  G01N33/76 ,  G01N2021/7793

摘要： A flexible, integrated, urine-based diagnostic device designed such that one or more diagnostic channels are integrated into the body of the device. Each diagnostic channel is designed to contain an immunoassay to detect the presence of a selected analyte so that the device can return a visible readout indicating the presence of the analyte. The flexibility of the device aids the user in the sample collection process.

摘要翻译： 一种灵活的，集成的基于尿液的诊断装置，设计成使得一个或多个诊断通道被集成到装置的主体中。 每个诊断通道被设计成包含用于检测所选分析物的存在的免疫测定，使得该装置可返回指示分析物存在的可见读数。 设备的灵活性有助于用户进行采样过程。

公开(公告)号：US20160313307A1

公开(公告)日：2016-10-27

申请号：US14694938

申请日：2015-04-23

申请人： Ted Titmus ,  William Pat Price

发明人： Ted Titmus ,  William Pat Price

IPC分类号： G01N33/52 ,  G01N21/64 ,  G01N33/543 ,  G01N21/78

CPC分类号： G01N33/521 ,  G01N21/8483 ,  G01N33/54366 ,  G01N2021/7759 ,  G01N2021/7793

摘要： Some embodiments provide for a diagnostic test strip having a carrier strip, one or more test pads, and one or more boundary projections which have an opening such that the boundary projections substantially surrounds three sides of each of the one or more test pads. Other embodiments provide for a method of detecting analytes in a patient sample, the method involving contacting an embodiment of a diagnostic test strip with a patient's tongue such that the tongue contacts one or more test pads and reading the results of the analysis from the diagnostic test strip.

摘要翻译： 一些实施例提供了具有载体带，一个或多个测试垫和一个或多个边界突起的诊断测试条，所述边界突起具有开口，使得边界突起基本上围绕一个或多个测试垫中的每一个的三个边。 其他实施例提供了一种检测患者样品中分析物的方法，所述方法包括将诊断测试条的实施例与患者的舌接触，使得舌接触一个或多个测试垫并从诊断测试读取分析结果 跳闸。