公开(公告)号：US08665432B2

公开(公告)日：2014-03-04

申请号：US12915148

申请日：2010-10-29

Applicant: Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

Inventor： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

IPC: G01N21/65

CPC classification number: G01J3/44 ,  G01N21/658

Abstract: An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.

Abstract translation: 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。

公开(公告)号：US20140036263A1

公开(公告)日：2014-02-06

申请号：US13563362

申请日：2012-07-31

Applicant: Ansoon KIM ,  Zhiyong Li ,  Steven J. Barcelo ,  Zhang-Lin Zhou ,  Gary Gibson

Inventor： Ansoon KIM ,  Zhiyong Li ,  Steven J. Barcelo ,  Zhang-Lin Zhou ,  Gary Gibson

IPC: G01J3/44 ,  B23P11/00 ,  G01N30/00

CPC classification number: G01N21/658 ,  G01N2021/775 ,  Y10T29/49826

Abstract: According to an example, an apparatus for performing spectroscopy includes a structure having an opening. The apparatus also includes a plurality of surface-enhanced Raman spectroscopy (SERS) elements positioned within the structure and a porous membrane covering the opening and the plurality of SERS elements. The porous membrane is to allow a predetermined analyte to reach the SERS elements while substantially preventing other analytes from reaching the SERS elements.

Abstract translation: 根据示例，用于执行光谱的装置包括具有开口的结构。 该装置还包括位于结构内的多个表面增强拉曼光谱（SERS）元件和覆盖该开口的多孔膜和多个SERS元件。 多孔膜是允许预定的分析物到达SERS元素，同时基本上防止其它分析物到达SERS元件。

公开(公告)号：US20140036262A1

公开(公告)日：2014-02-06

申请号：US13562567

申请日：2012-07-31

Applicant: Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Huei Pei Kuo ,  Zhang-Lin Zhou ,  R Stanley Williams

Inventor： Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Huei Pei Kuo ,  Zhang-Lin Zhou ,  R Stanley Williams

IPC: G01J3/44

CPC classification number: G01N21/658

Abstract: An apparatus for surface enhanced Raman spectroscopy includes a substrate, a nanostructure and a plasmonic material. The nanostructure and the plasmonic material are integrated together to provide electronic and plasmonic enhancement to a Raman signal produced by electromagnetic radiation scattering from an analyte.

Abstract translation: 用于表面增强拉曼光谱的装置包括底物，纳米结构和等离子体激元材料。 将纳米结构和等离子体激元材料集成在一起，以对由分析物的电磁辐射散射产生的拉曼信号提供电子和等离子体增强。

公开(公告)号：US20140029002A1

公开(公告)日：2014-01-30

申请号：US13561561

申请日：2012-07-30

Applicant: Shih-Yuan Wang ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Gary Gibson ,  Huei Pei Kuo ,  Zhang-Lin Zhou ,  Steven J. Barcelo ,  Ansoon Kim ,  R Stanley Williams

Inventor： Shih-Yuan Wang ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Gary Gibson ,  Huei Pei Kuo ,  Zhang-Lin Zhou ,  Steven J. Barcelo ,  Ansoon Kim ,  R Stanley Williams

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00

Abstract: A sensor for surface enhanced Raman spectroscopy (SERS) sensor includes surfaces and an actuator to adjust an intersurface spacing between the surfaces to contain an analyte and allow the analyte to be released from containment.

Abstract translation: 用于表面增强拉曼光谱（SERS）传感器的传感器包括表面和致动器，以调节表面之间的表面间隔，以包含分析物并允许分析物从容纳物释放。

公开(公告)号：US20140024131A1

公开(公告)日：2014-01-23

申请号：US14006721

申请日：2011-03-23

Applicant: Ansoon Kim ,  Zhiyong Li ,  Stanley R. Williams

Inventor： Ansoon Kim ,  Zhiyong Li ,  Stanley R. Williams

IPC: G01N21/00

CPC classification number: G01N21/00 ,  G01N21/554 ,  G01N21/648 ,  G01N21/658

Abstract: A hybrid nanostructure for molecular analysis is disclosed. The structure includes a plurality of nanofingers wherein each nanofinger is coated with a metal coating, is attached at one end to a substrate, and is freely bendable along its length such that the second ends of each nanofinger are capable of movement toward each other to form a cavity. The structure further includes a nanoparticle trapped in the cavity. An array of hybrid nanostructures and a method for fabricating the hybrid nanostructures are also disclosed.

Abstract translation: 公开了用于分子分析的杂化纳米结构。 该结构包括多个纳米针，其中每个纳米针涂覆有金属涂层，其一端连接到基底，并且可沿其长度自由弯曲，使得每个纳米针的第二端能够朝向彼此移动以形成 一个空腔。 该结构还包括捕获在空腔中的纳米颗粒。 还公开了一系列混合纳米结构和制备混合纳米结构的方法。

公开(公告)号：US08559003B2

公开(公告)日：2013-10-15

申请号：US13384456

申请日：2009-09-17

Applicant: Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexandre M. Bratkovski

Inventor： Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexandre M. Bratkovski

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y30/00

Abstract: An electrically driven device for surface enhanced Raman spectroscopy includes a first electrode, a substrate positioned proximate to the first electrode, a plurality of cone shaped protrusions formed integrally with or on a substrate surface, a Raman signal-enhancing material coated on each protrusion, and a second electrode positioned relative to the first electrode at a predetermined distance. Each of the protrusions has a tip with a radius of curvature ranging from about 0.1 nm to about 100 nm. The second electrode is positioned relative to the first electrode such that the electrodes together produce an electric field when a voltage bias is applied therebetween. The electric field has a field distribution that creates a stronger field gradient at a region proximate to the tips than at other portions of the substrate.

Abstract translation: 用于表面增强拉曼光谱的电驱动装置包括第一电极，靠近第一电极定位的基板，与基底表面一体地形成的多个锥形突起，涂覆在每个突起上的拉曼信号增强材料，以及 相对于第一电极以预定距离定位的第二电极。 每个突起具有具有约0.1nm至约100nm范围的曲率半径的尖端。 第二电极相对于第一电极定位，使得当在其之间施加电压偏置时，电极一起产生电场。 电场具有场分布，其在靠近尖端的区域处产生比在衬底的其它部分更强的场梯度。

公开(公告)号：US08520202B2

公开(公告)日：2013-08-27

申请号：US13233671

申请日：2011-09-15

Applicant: Zhiyong Li

Inventor： Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: An asymmetrical-nanofinger device for surface-enhanced luminescence. The device includes a substrate, and a plurality of nanofingers coupled with the substrate. The plurality of nanofingers includes a primary nanofinger having a primary active-material cap, and a secondary nanofinger having a secondary active-material cap. An average diameter of the primary active-material cap is substantially greater than an average diameter of the secondary active-material cap. The primary nanofinger and secondary nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with an analyte molecule disposed between the primary active-material cap and the secondary active-material cap. A method for fabricating the asymmetrical-nanofinger device, and an optical apparatus including an optical component that includes the asymmetrical-nanofinger device are also provided.

Abstract translation: 用于表面增强发光的非对称纳米方形器件。 该器件包括衬底和与衬底耦合的多个纳米器件。 多个纳米针包括具有主要活性材料帽的初级纳米针，和具有次级活性材料帽的次级纳米针。 初级活性材料盖的平均直径基本上大于第二活性材料盖的平均直径。 多个纳米针的初级纳米针和次级纳米针将自动排列成紧密堆积的构型，分析物分子设置在主活性材料帽和辅助活性材料帽之间。 还提供了一种用于制造非对称纳米酮装置的方法，以及包括包括非对称纳米装置的光学部件的光学装置。

公开(公告)号：US08518724B2

公开(公告)日：2013-08-27

申请号：US13450414

申请日：2012-04-18

Applicant: Christopher J. Petti ,  Mohamed M. Hilali ,  Theodore Smick ,  Venkatesan Murali ,  Kathy J. Jackson ,  Zhiyong Li ,  Gopalakrishna Prabhu

Inventor： Christopher J. Petti ,  Mohamed M. Hilali ,  Theodore Smick ,  Venkatesan Murali ,  Kathy J. Jackson ,  Zhiyong Li ,  Gopalakrishna Prabhu

IPC: H01L21/00 ,  H01L31/00

CPC classification number: H01L31/1892 ,  H01L31/0747 ,  H01L31/1864 ,  Y02E10/50

Abstract: A semiconductor assembly is described in which a support element is constructed on a surface of a semiconductor lamina. Following formation of the thin lamina, which may have a thickness about 50 microns or less, the support element is formed, for example by plating, or by application of a precursor and curing in situ, resulting in a support element which may be, for example, metal, ceramic, polymer, etc. This is in contrast to pre-formed support element which is affixed to the lamina following its formation, or to a donor wafer from which the lamina is subsequently cleaved.Fabricating the support element in situ may avoid the use of adhesives to attach the lamina to a permanent support element. In some embodiments, this process flow allows the lamina to be annealed at high temperature, then to have an amorphous silicon layer formed on each face of the lamina following that anneal.

Abstract translation: 描述了半导体组件，其中在半导体层的表面上构造支撑元件。 形成厚度约为50微米或更小的薄层之后，例如通过镀覆或通过施加前体和原位固化来形成支撑元件，得到支撑元件，其可以用于 例如，金属，陶瓷，聚合物等。这与预先形成的支撑元件形成对比，该预制形成的支撑元件在其形成之后固定到层板上，或者与施加器晶片相接触，该晶片随后被切割。 原位制造支撑元件可以避免使用粘合剂将薄片附着到永久支撑元件上。 在一些实施例中，该工艺流程允许薄层在高温下退火，然后在该退火之后具有在层的每个表面上形成的非晶硅层。

公开(公告)号：US20130194570A1

公开(公告)日：2013-08-01

申请号：US13363006

申请日：2012-01-31

Applicant: Wei WU ,  Michael Josef Stuke ,  Zhiyong Li ,  James Elmer Abbott, JR. ,  Min Hu ,  Ansoon Kim

Inventor： Wei WU ,  Michael Josef Stuke ,  Zhiyong Li ,  James Elmer Abbott, JR. ,  Min Hu ,  Ansoon Kim

IPC: G01J3/44 ,  G01J3/28

CPC classification number: G01J3/44 ,  G01J3/0205 ,  G01J3/26

Abstract: An apparatus for performing spectroscopy includes an optical waveguide comprising a fluidic channel to receive a fluid sample, in which the optical waveguide is to propagate lightwaves at a set of frequencies. The apparatus also includes a wavelength selective device coupled to the optical waveguide, in which the wavelength selective device comprises a predetermined bandwidth and is to capture frequencies of light within the predetermined bandwidth. The apparatus further includes a detector coupled to the wavelength selective device to generate signals that identify the frequencies captured by the wavelength selective device.

Abstract translation: 用于执行光谱学的装置包括光波导，其包括用于接收流体样品的流体通道，其中光波导将以一组频率传播光波。 该装置还包括耦合到光波导的波长选择装置，其中波长选择装置包括预定带宽并且捕获预定带宽内的光的频率。 该装置还包括耦合到波长选择装置的检测器，以产生识别由波长选择装置捕获的频率的信号。

公开(公告)号：US08395768B2

公开(公告)日：2013-03-12

申请号：US12772161

申请日：2010-04-30

Applicant: Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

Inventor： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/1895 ,  G01N21/658

Abstract: A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.

Abstract translation: 散射光谱装置，系统和方法采用导模共振（GMR）和GMR光栅。 该装置包括具有亚波长光栅的GMR光栅和配置成接收由激发信号与与GMR光栅的表面相关联的分析物之间的相互作用产生的散射信号的一部分的光学检测器。 散射信号的接收部分的传播方向与GMR光栅内的激励信号的GMR耦合部分的传播方向基本上不同。 该系统包括该装置和光源。 该方法包括激励GMR光栅中的GMR，将激发信号的GMR耦合部分与分析物相互作用以产生散射信号并检测散射信号的一部分。