公开(公告)号：US10520440B2

公开(公告)日：2019-12-31

申请号：US14377524

申请日：2012-02-08

Applicant: Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

Inventor： Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

Abstract: Molecule sensing apparatus. The apparatus has first and second chambers, an input port extending into the first chamber, a fluid channel extending from the first chamber to the second chamber, and a surface-enhanced substrate in the second chamber.

公开(公告)号：US09709538B2

公开(公告)日：2017-07-18

申请号：US14239330

申请日：2011-09-30

Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

IPC: G01N31/22 ,  G01N21/64 ,  G01N21/65 ,  B01L3/00 ,  B82Y15/00

CPC classification number: G01N31/22 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/141 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0819 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  G01N2201/0227 ,  G01N2201/023 ,  Y10T436/25

Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.

公开(公告)号：US09678013B2

公开(公告)日：2017-06-13

申请号：US14394295

申请日：2012-04-20

Applicant: Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

Inventor： Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

IPC: G01N21/01 ,  G01N21/65 ,  G01N35/00 ,  B01L3/00 ,  G01N21/64

CPC classification number: G01N21/658 ,  B01L3/5088 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/161 ,  G01N21/648 ,  G01N35/00009 ,  G01N2035/00019

Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.

公开(公告)号：US09592001B2

公开(公告)日：2017-03-14

申请号：US14406601

申请日：2012-07-29

Applicant: Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

Inventor： Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

IPC: G01J3/44 ,  A61B5/1459 ,  G01N21/65 ,  A61B5/00

CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/6862 ,  G01N21/658

Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中分析物的存在。

公开(公告)号：US09310306B2

公开(公告)日：2016-04-12

申请号：US14006436

申请日：2011-03-24

Applicant: Zhiyong Li ,  Ivan Naumov ,  Farzad Parvaresh

Inventor： Zhiyong Li ,  Ivan Naumov ,  Farzad Parvaresh

IPC: G01J3/44 ,  G01N21/65 ,  B05D3/00

CPC classification number: G01N21/65 ,  B05D3/007 ,  G01N21/658

Abstract: An apparatus for use in sensing applications includes a substrate and a plurality of clusters arranged in an aperiodic configuration on the substrate, wherein each of the plurality of clusters is formed of a plurality of Raman-active material nano-particles, and wherein each of the Raman-active material nano-particles is positioned in a substantially ordered configuration with respect to each other in each of the respective plurality of clusters.

Abstract translation: 用于感测应用的装置包括基板和在基板上以非周期配置布置的多个簇，其中多个簇中的每一个由多个拉曼活性材料纳米颗粒形成，并且其中 拉曼活性材料纳米颗粒在相应的多个簇中的每一个中相对于彼此定位成基本排列的构型。

公开(公告)号：US20150241355A1

公开(公告)日：2015-08-27

申请号：US14406653

申请日：2012-07-31

Applicant: Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

Inventor： Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

IPC: G01N21/65 ,  A61F2/02 ,  A61F2/82 ,  G02B5/10

CPC classification number: G01N21/658 ,  A61F2/02 ,  A61F2/82 ,  G01N2201/068 ,  G02B5/10 ,  Y10T29/49826

Abstract: According to an example, an apparatus for performing spectroscopy includes a parabolic reflector and a plurality of surface-enhanced Raman spectroscopy (SERS) elements spaced from the parabolic reflector and positioned substantially at a focal point of the parabolic reflector. The parabolic reflector is to reflect Raman scattered light emitted from molecules in a near field generated by the plurality of SERS elements to substantially increase the flux of the Raman scattered light emitted out of the apparatus.

Abstract translation: 根据一个实例，用于执行光谱学的装置包括抛物面反射器和与抛物面反射器间隔开并且基本上位于抛物面反射器的焦点的多个表面增强拉曼光谱（SERS）元件。 抛物面反射器是反射由多个SERS元件产生的近场中的分子发射的拉曼散射光，以大大增加从该装置发出的拉曼散射光的通量。

公开(公告)号：US09001324B2

公开(公告)日：2015-04-07

申请号：US13810982

申请日：2010-07-30

Applicant: Zhiyong Li ,  Min Hu ,  Wei Wu

Inventor： Zhiyong Li ,  Min Hu ,  Wei Wu

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: A surface enhanced Raman spectroscopy (SERS) probe apparatus and a method of SERS probing employ Raman-active surfaces of a plurality of nanoscale field concentrator (NFC) structures at a terminal end of an optical fiber. The SERS probe apparatus includes an optical fiber having an optical path and a terminal end that terminates the optical path. The SERS probe apparatus further includes a plurality of NFC structures and nanoparticles on surfaces of the plurality of NFC structures. First ends of the NFC structures are adjacent to the terminal end of optical fiber. The nanoparticles are Raman active to an analyte.

Abstract translation: 表面增强拉曼光谱（SERS）探针装置和SERS探测的方法在光纤的末端使用多个纳米尺度场集中器（NFC）结构的拉曼活性表面。 SERS探针装置包括具有光路的光纤和终止光路的终端。 SERS探针装置还包括在多个NFC结构的表面上的多个NFC结构和纳米颗粒。 NFC结构的第一端与光纤的终端相邻。 纳米颗粒是对分析物有活性的拉曼。

公开(公告)号：US09000411B2

公开(公告)日：2015-04-07

申请号：US13130799

申请日：2009-01-06

Applicant: Zhiyong Li ,  Alexandre M. Bratkovski ,  Jianhua Yang

Inventor： Zhiyong Li ,  Alexandre M. Bratkovski ,  Jianhua Yang

IPC: H01L45/00 ,  H01L27/24 ,  H01L29/06 ,  G11C11/00 ,  B82Y10/00

CPC classification number: H01L29/0665 ,  B82Y10/00 ,  H01L27/2472 ,  H01L29/0673 ,  H01L29/068 ,  H01L45/08 ,  H01L45/1233 ,  H01L45/146 ,  H01L45/147

Abstract: Various embodiments of the present invention are direct to nanoscale, reconfigurable, two-terminal memristor devices. In one aspect, a device (400) includes an active region (402) for controlling the flow of charge carriers between a first electrode (104) and a second electrode (106). The active region is disposed between the first electrode and the second electrode and includes a storage material. Excess mobile oxygen ions formed within the active region are stored in the storage material by applying a first voltage.

Abstract translation: 本发明的各种实施例直接涉及纳米尺度，可重新配置的两端忆阻器件。 一方面，装置（400）包括用于控制第一电极（104）和第二电极（106）之间的电荷载流子的有源区（402）。 有源区域设置在第一电极和第二电极之间，并且包括存储材料。 通过施加第一电压，在活性区域内形成的多余的移动氧离子被储存在存储材料中。

公开(公告)号：US20140375990A1

公开(公告)日：2014-12-25

申请号：US14381009

申请日：2012-03-06

Applicant: R. Stanley Williams ,  Zhiyong Li

Inventor： R. Stanley Williams ,  Zhiyong Li

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65

CPC classification number: G01J3/0205 ,  G01J3/44 ,  G01J3/4412 ,  G01N21/658 ,  G01N2201/06113 ,  G01N2201/068

Abstract: A double-grating surface-enhanced Raman spectrometer. The spectrometer includes a substrate; a plurality of nanofingers carried by the substrate, the nanofingers arranged to define a first optical grating; a light source oriented to project a beam of light toward the first optical grating; a second optical grating oriented to receive a beam of light scattered from the first optical grating; and a detector oriented to receive a beam of light scattered from the second optical grating.

Abstract translation: 双光栅表面增强拉曼光谱仪。 光谱仪包括基片; 由衬底承载的多个纳米装置，所述纳米装置布置成限定第一光栅; 光源，其朝向所述第一光栅投影光束; 第二光栅，其被定向为接收从第一光栅散射的光束; 以及用于接收从第二光栅散射的光束的检测器。

公开(公告)号：US08735858B2

公开(公告)日：2014-05-27

申请号：US13383616

申请日：2010-04-30

Applicant: Dmitri B. Strukov ,  Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

Inventor： Dmitri B. Strukov ,  Alexandre M. Bratkovski ,  R. Stanley Williams ,  Zhiyong Li

IPC: H01L29/02 ,  H01L47/00 ,  H01L23/58 ,  H01L21/326 ,  H01L21/479 ,  H01L21/425

CPC classification number: H01L45/08 ,  G02F1/13471 ,  H01L45/085 ,  H01L45/14 ,  H01L45/142 ,  H01L45/146

Abstract: An ionic device includes a layer of an ionic conductor containing first and second species of impurities. The first species of impurity in the layer is mobile in the ionic conductor, and a concentration profile of the first species determines a functional characteristic of the device. The second species of impurity in the layer interacts with the first species within the layer to create a structure that limits mobility of the first species in the layer.

Abstract translation: 离子装置包括含有第一和第二种杂质的离子导体层。 层中的第一种杂质可以在离子导体中移动，并且第一种类的浓度分布决定了器件的功能特性。 层中的第二种杂质与层内的第一种物质相互作用，以产生限制层中第一种类的迁移率的结构。