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公开(公告)号:US11998274B2
公开(公告)日:2024-06-04
申请号:US17266973
申请日:2019-08-07
Applicant: Kowa Company, Ltd.
Inventor: Kazunori Matsumura , Akio Kawakami
CPC classification number: A61B3/112 , A61B3/0008 , A61B3/15
Abstract: An ophthalmic photographing apparatus enables easy detection of a pupil diameter. The ophthalmic photographing apparatus is provided with an anterior ocular segment illumination unit for illuminating an anterior ocular segment of a subject eye with invisible light, an imaging element that is sensitive to at least invisible light and captures an image of the subject eye, and a processing unit for processing the image captured by the imaging element. When an image of an index projected onto the anterior ocular segment satisfies a predetermined condition, the processing unit starts detection of a pupil diameter of the subject eye by using the image on the imaging element formed by invisible light reflected from the anterior ocular segment.
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公开(公告)号:US20240085655A1
公开(公告)日:2024-03-14
申请号:US18262889
申请日:2022-01-27
Applicant: Kowa Company, Ltd.
Inventor: Jun TAKAYAMA , Syuichi TOMINAGA
IPC: G02B7/02
Abstract: According to one or more embodiments of the disclosure, a lens barrel includes an operation member and a knob. The operation member is disposed to be rotatable in a circumferential direction with respect to a lens barrel body. The knob is restricting and fixing rotation of the operation member in the circumferential direction. The lens barrel further includes a knob falling-off prevention member capable of switching between a first state of making the knob detachable from the lens barrel body and a second state of making the knob non-detachable from the lens barrel body.
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公开(公告)号:US11926927B2
公开(公告)日:2024-03-12
申请号:US16957990
申请日:2018-12-18
Inventor: Taiyo Yoshioka , Tsunenori Kameda , Akimune Asanuma , Hironori Sassa
Abstract: Developed and provided is a method of collecting a large amount of high-quality bagworm silk threads having no contaminant from bagworm nests in a convenient manner and at low cost. The habit of bagworms is utilized to allow a bagworm to build a nest using solvent-soluble substances or thermally meltable substances as nest materials, followed by dissolving or melting the nest materials to separate the nest material from the bagworm silk threads, whereby only pure bagworm silk threads constituting the bagworm nest can be obtained.
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公开(公告)号:US20240041857A1
公开(公告)日:2024-02-08
申请号:US18489303
申请日:2023-10-18
Applicant: National University Corporation Hamamatsu University School of Medicine , Kowa Company, Ltd.
Inventor: Naoki Unno , Hiroki Tanaka , Tatsuro Yata , Keisuke Inoue , Yuichi Makinose , Noboru Kaneta
IPC: A61K31/4704 , A61P9/14
CPC classification number: A61K31/4704 , A61P9/14
Abstract: The present invention addresses the problem of providing a therapeutic agent for abdominal aortic aneurysms, with which pharmacotherapy is possible.
The present invention provides a therapeutic agent for an aortic aneurysm comprising, as an active component, (−)-6-[3-[3-cyclopropyl-3-[(1R,2R)-2-hydroxycyclohexyl]ureido]propoxy]-2(1H)-quinolinone or a salt thereof, or a solvate of these.-
公开(公告)号:US11759456B2
公开(公告)日:2023-09-19
申请号:US16627128
申请日:2018-06-29
Applicant: KOWA COMPANY, LTD.
Inventor: Shin Sugimoto , Akito Minamizono
CPC classification number: A61K31/423 , A61K9/20 , A61K47/02 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38
Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition contains pemafibrate, a salt thereof or a solvate thereof in an amount of 0.017 to 4.2 mass % in terms of a free form of pemafibrate with respect to the total mass of the pharmaceutical composition.
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公开(公告)号:US20230287599A1
公开(公告)日:2023-09-14
申请号:US18246733
申请日:2021-09-30
Inventor: Taiyo YOSHIOKA , Tsunenori KAMEDA , Akimune ASANUMA , Norihiko FUKUOKA
IPC: D01B7/06
CPC classification number: D01B7/06 , A01K67/04 , D10B2211/04
Abstract: A movement control method and a spinning position control method for a bagworm is provided, in which a bagworm is led to a predetermined position and allowed to spin a foothold silk thread at the predetermined position. A behavior control method in which a light is radiated to a bagworm to lead the bagworm toward a direction from which the light is radiated, and a spinning position control method in which a light is radiated to a bagworm at a spinning position on a surface of a base material to allow the bagworm to spin at the position are also provided.
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公开(公告)号:US11732096B2
公开(公告)日:2023-08-22
申请号:US16644055
申请日:2018-08-30
Inventor: Taiyo Yoshioka , Tsunenori Kameda , Tamako Hata , Akimune Asanuma , Norihiko Fukuoka
CPC classification number: C08J5/048 , C08J5/042 , C08J5/045 , C08J5/247 , C08L23/0853 , C08J2323/08 , C08J2489/00 , C08L2205/16
Abstract: An object of the present invention is to develop and provide a fiber-reinforced composite material having an “elongation” feature in addition to a high strength and a high elastic modulus. Further, an object of the present invention is to address problems of brittleness and peeling in the conventional fiber-reinforced composite materials. A fiber-reinforced composite material containing the bagworm silk thread as reinforcing fibers is provided.
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公开(公告)号:US11717152B2
公开(公告)日:2023-08-08
申请号:US16627683
申请日:2018-07-03
Applicant: KOWA COMPANY, LTD.
Inventor: Katsumi Yabusaki
CPC classification number: A61B3/101 , A61B3/14 , G06T7/0012 , G06T2207/10024 , G06T2207/30041
Abstract: A method, a computer program and a device for evaluating a tear fluid layer non-invasively. The method, computer program, and device include a step of detecting a time when color information in a predetermined region in a tear fluid layer interference fringe image changes by a threshold value or more as an eyelid opening time, a step of extracting an image at the time when the predetermined time has passed from the eyelid opening time as an extracted image from the tear fluid interference fringe images, a determination value calculation step of calculating a determination value from the color information in a pixel in a local region by scanning a predetermined target region, a step of detecting a corresponding pixel by comparing the calculated determination value and a threshold value, and an evaluation step of evaluating tear fluid layer breakdown by comparing the detected pixel and a threshold value.
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189.
公开(公告)号:US20230220590A1
公开(公告)日:2023-07-13
申请号:US18000321
申请日:2021-06-01
Inventor: Taiyo YOSHIOKA , Tsunenori KAMEDA , Takahiro KITAMURA , Akimune ASANUMA
CPC classification number: D01B7/04 , D01D10/0454 , D01D11/06 , D01F11/02 , D01F4/00 , D10B2211/04
Abstract: An object of the present invention is to develop: a method of efficiently producing a long bagworm silk thread without slack of reeling during collection while preventing a change in the spinning direction and the runaway of the bagworm from a rail, and alleviating a burden on the bagworm; and an apparatus for implementing the thread-producing method. Provided is an apparatus for producing a bagworm silk thread, including: a movable loop-shaped rail configured to move in the longitudinal direction and to be held by the legs of a bagworm; a fixator configured to fix the bagworm; and an adhesion controller configured to store an adhesion control solution for washing away or removing a gummy component from the bagworm silk thread spun on the movable loop-shaped rail, wherein the apparatus makes it possible to cumulate the bagworm silk thread spun on the movable loop-shaped rail.
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公开(公告)号:US20230092776A1
公开(公告)日:2023-03-23
申请号:US17885498
申请日:2022-08-10
Applicant: Kowa Company, Ltd.
Inventor: Ryu Oshima , Kazuhito Suehira , Gary Gordon
IPC: A61K31/423 , A61K9/00 , A61P3/06
Abstract: The present invention relates to pharmacological interventions with pemafibrate for moderate or severe hypertriglyceridemia.
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