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公开(公告)号：US20160082033A1
公开(公告)日：2016-03-24
申请号：US14855065
申请日：2015-09-15
Applicant: Alltech, Inc.
Inventor： Ronan Power , Zi-Jian Lan
IPC: A61K31/7076
CPC classification number: A61K31/7135 , A61K31/28 , A61K31/706 , A61K31/7064 , A61K31/7076 , A61K38/05 , A61K38/28 , C07D473/34
Abstract: The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, a compound of Formula (I), and combinations thereof, and methods of using the same for inhibiting β amyloid aggregation, ApoE4 expression, p38 or Tau protein phosphorylation, or increasing Neprilysin and Insulin Degrading Enzyme expression.
Abstract translation: 本申请涉及包含硒化合物的组合物，例如5'-甲基硒腺嘌呤，式（I）化合物及其组合，以及其用于抑制β-葡聚糖的方法。 淀粉样蛋白聚集，ApoE4表达，p38或Tau蛋白磷酸化，或增加Neprilysin和胰岛素降解酶表达。
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公开(公告)号：US20160045533A1
公开(公告)日：2016-02-18
申请号：US14855128
申请日：2015-09-15
Applicant: Alltech, Inc.
Inventor： Ronan Power , Zi-Jian Lan
IPC: A61K31/7135 , A61K31/28 , A61K38/28 , A61K31/7076
CPC classification number: A61K31/7135 , A61K31/28 , A61K31/706 , A61K31/7064 , A61K31/7076 , A61K38/05 , A61K38/28 , C07D473/34
Abstract: The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, Gamma-glutamyl-methylseleno-cysteine, a compound of Formula (I), Formula (II), or Formula (III), and combinations thereof, and methods of using the same for modulating glucose metabolism in a subject.
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公开(公告)号：US20150168364A1
公开(公告)日：2015-06-18
申请号：US14109907
申请日：2013-12-17
Applicant: Alltech, Inc.
Inventor： Kyle McKinney , Allyson Lovell , Benjamin Henry , Patrick Becker , Rebecca A. Timmons
Abstract: The present application provides systems and methods for analyzing animal feeds and for adjusting animal feeds to improve the digestibility of animal feed components. Digestibility of animal feed can be determined by performing in vitro digestion of the feed and analyzing concentrations of residual components in the digested feed by NIR spectroscopy. Animal feed compositions can be adjusted to improve digestibility of components in the feed. The systems and methods of the present application can be used to determine the effect of an additive on the digestibility of feed.
Abstract translation: 本申请提供了用于分析动物饲料和调整动物饲料以提高动物饲料组分的消化率的系统和方法。 动物饲料的消化率可以通过进行饲料的体外消化和通过NIR光谱分析消化的饲料中残留组分的浓度来测定。 可以调节动物饲料组合物以改善饲料中组分的消化率。 本申请的系统和方法可用于确定添加剂对饲料消化率的影响。
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公开(公告)号：US20140273048A1
公开(公告)日：2014-09-18
申请号：US14109359
申请日：2013-12-17
Applicant: Alltech, Inc.
Inventor： Kyle McKinney , Allyson Lovell , Benjamin Henry , Patrick Becker , Rebecca A. Timmons
IPC: C12Q1/37
CPC classification number: C12Q1/37 , G01N1/4044 , G01N21/3563 , G01N21/359 , G01N33/02 , G01N2333/96477
Abstract: The present invention relates to systems and methods for analyzing animal feeds. In particular, the present disclosure relates to in vitro systems and methods for analyzing animal feed for metabolism of nutrients and energy sources.
Abstract translation: 本发明涉及用于分析动物饲料的系统和方法。 特别地，本公开涉及用于分析动物饲料用于营养物质和能源的代谢的体外系统和方法。
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公开(公告)号：US11613552B2
公开(公告)日：2023-03-28
申请号：US17238354
申请日：2021-04-23
Applicant: Alltech, Inc.
Inventor： Zi-Jian Lan , Ronan Power , Alexandros Yiannikouris , Thirupathi Reddy Yerramreddy
IPC: A61K31/7076 , C07H19/16 , A61P3/10 , C07H19/167
Abstract: The present disclosure provides compounds of formulas (1)-(3), and compositions and methods of use thereof. The present disclosure also provides methods of preparing a provided compound and composition, and methods of characterizing a provided compound and composition.
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Patent Agency Ranking
公开(公告)号：US10201558B2
公开(公告)日：2019-02-12
申请号：US14855065
申请日：2015-09-15
Applicant: Alltech, Inc.
Inventor： Ronan Power , Zi-Jian Lan
IPC: A61K31/28 , A61K38/05 , A61K38/28 , C07D473/34 , A61K31/7076 , A61K31/7135 , A61K31/706 , A61K31/7064
Abstract: The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, a compound of Formula (I), and combinations thereof, and methods of using the same for inhibiting β amyloid aggregation, ApoE4 expression, p38 or Tau protein phosphorylation, or increasing Neprilysin and Insulin Degrading Enzyme expression.
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17.发明申请SYSTEMS AND METHODS FOR ESTIMATING FEED EFFICIENCY AND CARBON FOOTPRINT FOR MEAT PRODUCING ANIMAL 审中-公开用于估算生产动物的饲料效率和碳肥的系统和方法公开(公告)号：US20160324188A1
公开(公告)日：2016-11-10
申请号：US15108976
申请日：2014-12-31
Applicant: ALLTECH, INC.
CPC classification number: A23K20/10 , A01K29/005 , A23K10/00 , A23K50/10 , G06Q10/06 , G06Q10/063
Abstract: Systems and methods for estimating meat producing animal feed conversion efficiency and carbon footprint, such as to allow adjustments to be made in the animals feed to improve meat production, reduce waste, and/or reduce the carbon footprint. In embodiments of the present application, a system is provided that integrates a digestion model of an animal feed with weight gain efficiency and carbon footprint. Such systems and methods are useful to analyze and compare different animal feed compositions that differ from one another in one or more components and/or to analyze the effect of the addition of a feed supplement on weight gain efficiency and/or carbon footprint. In embodiments, the systems and methods described herein provide a feed parameter-carbon footprint compromise. A feed parameter-carbon footprint compromise is useful to adjust animal feed composition by balancing weight gain efficiency with effects on carbon footprint. Different feed supplements or amounts of feed supplements, and/or different feed compositions are selected based on the desired feed parameter-carbon footprint compromise.
Abstract translation: 用于估计肉类生产动物饲料转化效率和碳足迹的系统和方法，例如允许在动物饲料中进行调整以改善肉类生产，减少浪费和/或减少碳足迹。 在本申请的实施例中，提供了一种将动物饲料的消化模型与增重效率和碳足迹相结合的系统。 这样的系统和方法可用于分析和比较在一种或多种组分中彼此不同的不同动物饲料组合物和/或分析添加饲料补充剂对体重增加效率和/或碳足迹的影响。 在实施例中，本文所述的系统和方法提供进料参数 - 碳足迹损害。 饲料参数 - 碳足迹损害是通过平衡体重增加效率和碳足迹的影响来调整动物饲料组成的。 基于所需的进料参数 - 碳足迹损害来选择不同的饲料添加剂或饲料添加剂的量，和/或不同的饲料组合物。
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18.发明申请公开(公告)号：US20140348872A1
公开(公告)日：2014-11-27
申请号：US14456718
申请日：2014-08-11
Applicant: Alltech, Inc.
Inventor： Thomas P. Lyons , Ronan Power
IPC: A61K36/064
CPC classification number: A61K36/064 , A61K33/04 , A61K36/06 , A61K48/00
Abstract: The present invention relates to compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). For example, the present invention provides compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same for treating and/or preventing one or more conditions (e.g., problems) disorders, and/or diseases related to establishing and/or maintaining a pregnancy. Compositions and methods of the present invention find use in, among other things, research and clinical (e.g., preventative and therapeutic) applications.
Abstract translation: 本发明涉及包含硒（例如有机硒（例如，硒化酵母（例如，SEL-PLEX））的组合物）及其使用方法（例如，作为治疗和/或预防性治疗）。 例如，本发明提供了包含硒（例如有机硒（例如，硒化酵母（例如，SEL-PLEX））的组合物）和使用该组合物治疗和/或预防一种或多种病症（例如问题）的方法， 疾病和/或与建立和/或维持怀孕相关的疾病。 本发明的组合物和方法尤其可用于研究和临床（例如预防和治疗）应用。
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公开(公告)号：US10537122B2
公开(公告)日：2020-01-21
申请号：US14109907
申请日：2013-12-17
Applicant: Alltech, Inc.
Inventor： Kyle McKinney , Allyson Lovell , Benjamin Henry , Patrick Becker , Rebecca A. Timmons
IPC: A23K10/14
Abstract: The present application provides systems and methods for analyzing animal feeds and for adjusting animal feeds to improve the digestibility of animal feed components. Digestibility of animal feed can be determined by performing in vitro digestion of the feed and analyzing concentrations of residual components in the digested feed by NIR spectroscopy. Animal feed compositions can be adjusted to improve digestibility of components in the feed. The systems and methods of the present application can be used to determine the effect of an additive on the digestibility of feed.
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公开(公告)号：US10201559B2
公开(公告)日：2019-02-12
申请号：US15121412
申请日：2014-03-14
Applicant: Alltech, Inc.
Inventor： Ronan Power , Zi-Jian Lan , Alexandros Yiannikouris
IPC: A01N43/04 , A61K31/70 , A61K31/7135 , A61K31/7076 , C07D473/34 , A61K31/28 , A61K38/05 , A61K38/28 , A61K31/706 , A61K31/7064
Abstract: The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, Gamma-glutamyl-methylseleno-cysteine, a compound of formula (I), formula (II), a compound of formula (III) and combinations thereof, and methods of using the same in enhancing mitochondrial function, or treating mitochondrial dysfunction.
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