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    Axial length measurement monitor
    11.
    发明授权
    Axial length measurement monitor 有权

    公开(公告)号：US11497396B2

    公开(公告)日：2022-11-15

    申请号：US17647585

    申请日：2022-01-10

    Applicant: ACUCELA INC.

    Inventor： Ryo Kubota ,  Philip M. Buscemi ,  Matthias Pfister ,  Stephan Wyder ,  Amitava Gupta

    IPC: G01B9/02 ,  A61B3/10 ,  G01B9/02091

    Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).

    ARTIFICIAL INTELLIGENCE FOR EVALUATION OF OPTICAL COHERENCE TOMOGRAPHY IMAGES
    12.
    发明申请
    ARTIFICIAL INTELLIGENCE FOR EVALUATION OF OPTICAL COHERENCE TOMOGRAPHY IMAGES 有权

    公开(公告)号：US20220301161A1

    公开(公告)日：2022-09-22

    申请号：US17805299

    申请日：2022-06-03

    Applicant: ACUCELA INC.

    Inventor： Stephan WYDER ,  Matthias PFISTER ,  Cyril STOLLER ,  Philip M. BUSCEMI

    IPC: G06T7/00 ,  G06T7/11 ,  G06T3/00 ,  G06N3/08 ,  G16H30/40

    Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.

    PROJECTION OF DEFOCUSED IMAGES ON THE PERIPHERAL RETINA TO TREAT REFRACTIVE ERROR
    17.
    发明申请
    PROJECTION OF DEFOCUSED IMAGES ON THE PERIPHERAL RETINA TO TREAT REFRACTIVE ERROR 有权

    公开(公告)号：US20210382325A1

    公开(公告)日：2021-12-09

    申请号：US17304691

    申请日：2021-06-24

    Applicant: ACUCELA INC.

    Inventor： Ryo KUBOTA ,  Nabin JOSHI ,  Arkady SELENOW ,  Steve ALI ,  Stefan BAUER ,  Jean-Noël FEHR ,  Moritz HAEBERLI ,  Patrizia WEBER ,  Julien SAUVET ,  Amitava GUPTA

    IPC: G02C7/06 ,  G02C11/04 ,  G02C7/02

    Abstract: An apparatus to treat refractive error of the eye comprises one or more optics configured to project stimuli comprising out of focus images onto the peripheral retina outside the macula. While the stimuli can be configured in many ways, in some embodiments the stimuli are arranged to decrease interference with central vison such as macular vision. The stimuli can be out of focus images may comprise an amount of defocus within a range from about 3 Diopters (“D”) to about 6 D. In some embodiments, the brightness of the stimuli is greater than a brightness of background illumination by an appropriate amount such as at least 3 times the background brightness. In some embodiments, each of a plurality of stimuli comprises a spatial frequency distribution with an amplitude profile having spatial frequencies within a range from about range of 1×10−1 to 2.5×101 cycles per degree.

    Scan pattern and signal processing for optical coherence tomography
    18.
    发明授权
    Scan pattern and signal processing for optical coherence tomography 有权

    公开(公告)号：US10959613B1

    公开(公告)日：2021-03-30

    申请号：US16947728

    申请日：2020-08-13

    Applicant: ACUCELA INC.

    Inventor： Ryo Kubota ,  Stephan Wyder ,  Philip M. Buscemi ,  Matthias Pfister ,  Alexander Holzer

    IPC: A61B3/10 ,  G01B9/02 ,  A61B3/12

    Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.

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