Abstract:
The invention relates to an injectable biomaterial. The injectable biomaterial of the invention comprises a non aqueous solvent which is compatible for injection to human being and nanoparticles made of a polymer which is insoluble in water and insoluble in said non aqueous solvent, said nanoparticles being loaded with a drug or a biological agent. The injectable biomaterial of the invention is particularly appropriate for occluding normal or malformative blood vessels or non circulating cavities or for necrosing tumors.
Abstract:
A method is provided for estimating the components of the force torsor that are applied to a bearing, which method provides for the measurement of a vector (Vm) of N deformations and for the use of a physical model linking a vector (Q) of at most N representative values of the components of the torsor with a deformation measurement vector, the method comprises the following iterative steps: introduction of a vector (Q) of representative values into the model in order to calculate a deformation measurement vector (Vc); and carrying out a pertinence test (T) between the deformation measurement vector (Vc) which is calculated and the measured vector (Vm); if the test (T) is negative, establishing at least one new vector (Q) of representative values to be introduced into the model according to the result of the test; or if the test (T) is positive, storing the vector (Q) of introduced values; wherein the estimated components of the force torsor are established according to at least one stored vector (Q) of values.
Abstract:
The present invention provides a biodegradable biopolymer matrix for surgical and/or therapeutic use comprising chitosan hydrochloride and dextran dialdehyde is in the ratio of 1:1 to 1:2. The invention further provides a process for preparing the biopolymer matrix and a kit for a surgical and/or therapeutic use comprising the biopolymer matrix.
Abstract:
The invention relates to injectable gel-forming compositions which contain an association of linear and cross-linked polymers and are embodied in the form of a suspension. The use of said compositions, in particular for filling pipes and cavities is also disclosed.
Abstract:
The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2═CR1)CO—K (1) wherein: K represents O—Z or NH—Z, Z representing (CR2R3)m-CH3, (CH2—CH2—O)m-H, (CH2—CH2—O)m-CH3, (CH2)m-NR4R5 with m representing an integer from 1 to 30; R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; (ii) at least between 0.1 and 50% mol, advantageously between 1 and 30% mol, more advantageously between 1 and 20 mol % of a cyclic monomer having a exomethylene group of formula (II) wherein: R6, R7, R8 and R9 represent independently H or a C5-C7 aryl group or R6 and R9 are absent and R7 and R8 form together with the carbon atom on which they are bonded a C5-C7 aryl group; i and j represent independently an integer chosen between 0 and 2; X represents either O or X is not present and in this latter case, CR6R7 and CR8R9 are linked via a single bond C—C and (iii) at least one bio-resorbable block copolymer cross-linker.
Abstract:
A method and an apparatus are disclosed for simultaneously cleaning multiple teeth, such as one or both dental arches. The Dental Cleaning Apparatus (DCA) includes a cleaning engine enclosed in a main housing, a fluid tube, and a mouthpiece. The cleaning engine includes a fluid circuit having a number of pumps and solenoid valves, and a programmable controller to control the solenoid valves and other operations. The fluid tube includes a number of separate tubes for injection and evacuation of cleaning fluid from the interior of mouthpiece. The mouthpiece is generally made from a flexible and supple material, such as silicone, and may have bristles of various shapes. The cleaning engine alternates the mouthpiece between a relaxation state and a contraction state to effectively scrub the surface of all enclosed teeth simultaneously. It may automatically learn and adjust the vacuum pressure needed for each user to optimize cleaning.
Abstract:
The present invention relates to a macromolecule-loaded bioresorbable crosslinked polymer wherein the polymer is obtainable from the polymerization of: (i) at least one monomer of formula (I) (CH2═CR1)CO—K wherein: —K represents O—Z or NH—Z, Z representing (CR2R3)m—CH3, (CH2—CH2—O)m—H, (CH2—CH2—O)m—CH3, (CH2)m—NR4R5 with m representing an integer from 1 to 30; —R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker, and wherein the macromolecule is chosen in the group consisting of proteins and nucleic acids.
Abstract:
The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2═CR1)CO—K (I) wherein: K represents 0-Z or NH—Z, Z representing (CR2R3)m—CH3, (CH2—CH2—O)m—H, (CH2—CH2—O)m—CH3, (CH2)m—NR4R5 with m representing an integer from 1 to 30; R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker.