利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

51 条记录 (耗时 0.022 秒)

    Stent comprising a coating system
    11.
    发明申请
    Stent comprising a coating system 审中-公开
    支架包括涂层系统

    公开(公告)号：US20060241742A1

    公开(公告)日：2006-10-26

    申请号：US10562376

    申请日：2004-06-14

    申请人： Claus Harder ,  Stephane Delaloye ,  Bernd Heublein

    发明人： Claus Harder ,  Stephane Delaloye ,  Bernd Heublein

    IPC分类号： A61F2/82

    CPC分类号： A61F2/82 ,  A61F2250/0035 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/602

    摘要： A stent comprises a tubular base body which is open on the front sides thereof and has a peripheral wall that is at least partially covered with a coating system consisting of at least one polymer carrier and at least one pharmacologically active substance, which is released into the surrounding tissue once the stent has been implanted in the human or animal body. The invention creates a coating system which enables an optimum local application of the active ingredient. A concentration of the substance, a morphological structure of the carrier(s), a material modification of the carrier(s), and/or a layer thickness of the carrier(s), are predetermined in the longitudinal direction of the stent, in such a way that the elution varies locally in the longitudinal direction of the stent and is determined according to the pathophysiological and/or rheological conditions to be expected during the application.

    摘要翻译： 支架包括在其前侧开口的管状基体，并且具有至少部分地覆盖有由至少一种聚合物载体和至少一种药理活性物质组成的涂层系统的周壁，其被释放到 一旦将支架植入人体或动物体内，就会围绕组织。 本发明产生一种涂覆系统，其能够最佳地局部施用活性成分。 物质的浓度，载体的形态结构，载体的材料改性和/或载体的层厚度在支架的纵向上是预定的，在 这样一种方式使得洗脱在支架的纵向上局部变化，并且根据在施用期间预期的病理生理学和/或流变学条件来确定。

    Stent
    12.
    发明授权
    Stent 失效
    支架

    公开(公告)号：US06896695B2

    公开(公告)日：2005-05-24

    申请号：US09804975

    申请日：2001-03-13

    申请人： Heinz Mueller ,  Claus Harder

    发明人： Heinz Mueller ,  Claus Harder

    IPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2/06

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558

    摘要： A stent, in particular a coronary stent, comprising at least two tubular portions which are arranged adjacently in the longitudinal direction of the stent and which comprise a plurality of interconnected, substantially cell-shaped elements which have an orientation and are connected together in the longitudinal direction of the stent by way of at least one first connecting means, wherein the elements are of such an arrangement and/or configuration that the ends of the elements which are in the longitudinal direction of the stent define an edge contour extending around the stent in a wave-like configuration in the peripheral direction thereof, and wherein the mutually adjoining edge contours of two tubular portions extend around the stent substantially in in-phase relationship.

    摘要翻译： 一种支架，特别是冠状支架，包括至少两个管状部分，其沿着支架的纵向方向相邻布置并且包括多个相互连接的基本上为细胞形状的元件，其具有取向并且在纵向方向上连接在一起 支架的方向通过至少一个第一连接装置，其中元件具有这样的布置和/或构造，使得沿着支架的纵向方向的元件的端部限定围绕支架延伸的边缘轮廓 沿圆周方向的波状构造，并且其中两个管状部分的相互邻接的边缘轮廓基本上以相位相位延伸围绕支架延伸。

    Stent and method and device for fabricating the stent
    13.
    发明授权
    Stent and method and device for fabricating the stent 有权

    公开(公告)号：US10098766B2

    公开(公告)日：2018-10-16

    申请号：US12510166

    申请日：2009-07-27

    申请人： Claus Harder

    发明人： Claus Harder

    IPC分类号： A61F2/82 ,  A61F2/915 ,  A61F2/91 ,  A61F2/06

    摘要： Stent, as well as a method and device for fabricating the stent, wherein the stent has a tubular lattice structure comprising individual struts and at least one strut of which at least one longitudinal section runs with at least one directional component in the radial circumferential direction of the stent, wherein the surface of the longitudinal section facing the outside of the stent is curved only about the longitudinal axis of the stent. According to the invention, the surface of longitudinal section of the strut, which surface faces the inside of the stent, has such a curvature that the strut cross section is fluidically optimized.

    Stent and method and device for fabricating the stent
    18.
    发明授权
    Stent and method and device for fabricating the stent 有权
    用于制造支架的支架和方法和装置

    公开(公告)号：US08641477B2

    公开(公告)日：2014-02-04

    申请号：US13457276

    申请日：2012-04-26

    申请人： Claus Harder

    发明人： Claus Harder

    IPC分类号： B24B1/00

    CPC分类号： A61F2/915 ,  A61F2/82 ,  A61F2/91 ,  A61F2002/068 ,  A61F2002/9155

    摘要： Stent, as well as a method and device for fabricating the stent, wherein the stent has a tubular lattice structure comprising individual struts and at least one strut of which at least one longitudinal section runs with at least one directional component in the radial circumferential direction of the stent, wherein the surface of the longitudinal section facing the outside of the stent is curved only about the longitudinal axis of the stent. According to the invention, the surface of longitudinal section of the strut, which surface faces the inside of the stent, has such a curvature that the strut cross section is fluidically optimized.

    摘要翻译： 支架以及用于制造支架的方法和装置，其中支架具有管状晶格结构，其包括单独的支柱和至少一个支柱，其中至少一个纵向截面沿着径向圆周方向的至少一个方向分量 支架，其中面向支架外侧的纵向截面的表面仅围绕支架的纵向轴线弯曲。 根据本发明，支柱的表面面向支架内侧的支柱的纵向截面的表面具有使支柱横截面流体优化的曲率。

    Implant and method for manufacturing same
    19.
    发明授权
    Implant and method for manufacturing same 有权
    种植体及其制造方法

    公开(公告)号：US08574616B2

    公开(公告)日：2013-11-05

    申请号：US12792510

    申请日：2010-06-02

    申请人： Ullrich Bayer ,  Claus Harder ,  Elisabeta Burean

    发明人： Ullrich Bayer ,  Claus Harder ,  Elisabeta Burean

    IPC分类号： A61F2/00 ,  A61F2/06 ,  A61L33/00

    CPC分类号： A61K9/0012 ,  A61K33/00 ,  A61L31/022 ,  A61L31/146 ,  A61L31/16

    摘要： The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body containing metallic material, preferably iron. The following manufacturing method is provided for promotion of the anti-inflammatory effect of the implant: (i) providing the body of the implant; (ii) producing an at least partially closed pore structure in a portion of the structure of the implant body close to the surface; and (iii) incorporating NOX into the cavities of the pore structure. Also described is an implant manufactured in this manner.

    摘要翻译： 本发明涉及用于制造植入物的方法，特别是管腔内假体，其具有包含金属材料，优选铁的主体。 提供以下制造方法用于促进植入物的抗炎作用：（i）提供植入物的主体; （ii）在所述植入体的结构的靠近所述表面的部分结构中产生至少部分闭合的孔结构; 和（iii）将NOX掺入到孔结构的空腔中。 还描述了以这种方式制造的植入物。

    Stent and Method and Device for Fabricating the Stent
    20.
    发明申请
    Stent and Method and Device for Fabricating the Stent 有权
    支架及其制造方法及装置

    公开(公告)号：US20120214384A1

    公开(公告)日：2012-08-23

    申请号：US13457276

    申请日：2012-04-26

    申请人： Claus Harder

    发明人： Claus Harder

    IPC分类号： B24B1/00

    CPC分类号： A61F2/915 ,  A61F2/82 ,  A61F2/91 ,  A61F2002/068 ,  A61F2002/9155

    摘要： Stent, as well as a method and device for fabricating the stent, wherein the stent has a tubular lattice structure comprising individual struts and at least one strut of which at least one longitudinal section runs with at least one directional component in the radial circumferential direction of the stent, wherein the surface of the longitudinal section facing the outside of the stent is curved only about the longitudinal axis of the stent. According to the invention, the surface of longitudinal section of the strut, which surface faces the inside of the stent, has such a curvature that the strut cross section is fluidically optimized.

    摘要翻译： 支架以及用于制造支架的方法和装置，其中支架具有管状晶格结构，其包括单独的支柱和至少一个支柱，其中至少一个纵向截面沿着径向圆周方向的至少一个方向分量 支架，其中面向支架外侧的纵向截面的表面仅围绕支架的纵向轴线弯曲。 根据本发明，支柱的表面面向支架内侧的支柱的纵向截面的表面具有使支柱横截面流体优化的曲率。