CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF
    11.
    发明申请
    CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF 有权
    CIS-2,6,6-二取代衍生物衍生物及其制备方法

    公开(公告)号:US20090209770A1

    公开(公告)日:2009-08-20

    申请号:US12243244

    申请日:2008-10-01

    CPC classification number: C07D309/06

    Abstract: Disclosed are cis-2,6-disubstituted tetrahydropyran derivatives represented by Chemical Formula 1 and a preparation method thereof. The tetrahydropyran derivatives can be prepared by Prins-reacting tetrahydropyran derivatives with homopargylicalcohol derivatives in the presence of trimethylsilyltriflate. The tetrahydropyran derivatives with cis-substituents at both C2 and C6 positions of the tetrahydropyran ring are useful as intermediates for use in the synthesis and development of therapeutically effective, naturally occurring compounds. (wherein, R1, R2 and R3 are as defined in the specification.)

    Abstract translation: 公开了由化学式1表示的顺式-2,6-二取代四氢吡喃衍生物及其制备方法。 四氢吡喃衍生物可以通过Prins-在三甲基甲硅烷基三氟甲磺酸酯存在下将四氢吡喃衍生物与高官能醇衍生物反应来制备。 在四氢吡喃环的C2和C6位上具有顺式取代基的四氢​​吡喃衍生物可用作合成和开发治疗有效的天然存在的化合物的中间体。 (其中,R1,R2和R3如说明书中所定义)

    Liquid crystal display device
    12.
    发明申请
    Liquid crystal display device 有权
    液晶显示装置

    公开(公告)号:US20090207365A1

    公开(公告)日:2009-08-20

    申请号:US12318567

    申请日:2008-12-31

    CPC classification number: G02F1/136286 G02F1/134363

    Abstract: A liquid crystal display device is disclosed. The disclosed liquid crystal display device includes gate lines, data lines formed to intersect with the gate lines, thereby defining sub-pixel regions, vertical common lines formed in parallel to the data lines such that at least one vertical common line is arranged for one pixel region, which is constituted by at least three sub-pixel regions, thin film transistors each connected to a corresponding one of the gate lines and a corresponding one of the data lines, pixel electrodes each connected to a corresponding one of the thin film transistors, and common electrodes each connected to a corresponding one of the vertical common lines.

    Abstract translation: 公开了一种液晶显示装置。 所公开的液晶显示装置包括栅极线,形成为与栅极线相交的数据线,从而限定子像素区域,与数据线平行形成的垂直公共线,使得至少一个垂直公共线布置成一个像素 区域,其由至少三个子像素区域构成,每个连接到相应的一条栅极线的薄膜晶体管和相应的一条数据线,各自连接到相应的一个薄膜晶体管的像素电极, 以及各自连接到相应的一条垂直公共线的公共电极。

    IN-PLANE SWITCHING MODE LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR FABRICATING THE SAME
    13.
    发明申请
    IN-PLANE SWITCHING MODE LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR FABRICATING THE SAME 有权
    平面切换模式液晶显示装置及其制造方法

    公开(公告)号:US20080284967A1

    公开(公告)日:2008-11-20

    申请号:US12121441

    申请日:2008-05-15

    CPC classification number: G02F1/134363

    Abstract: The present invention shows that an in-plane switching mode LCD and a method for fabricating the same that substantially obviates one or more problems due to limitations and disadvantages of the related art.To achieve the purpose of the present invention, an in-plane switching mode LCD according to the present invention having a plurality of pixels arranged in a matrix includes a gate line formed on a lower substrate, a data line formed such that the data line intersect the gate line to define a pixel region, a TFT (Thin Film Transistor) formed at the intersection of the gate line and the data line, a pixel electrode connected to the TFT, a common electrode to generate a horizontal electric field with the pixel electrode, and a common line supplying common voltage to the common electrode, wherein the common line comprises a first common line formed parallel to the gate line in a lower portion of the pixel region, a second common line formed parallel to the date line in a side portion of the pixel region adjacent to the data line, and a third common line formed parallel to the gate line in a upper portion of the pixel region, and wherein the data line comprises a pair of sub-lines facing directly with each other in every two pixel regions.As above described, the present invention has an effect of increasing aperture ration by a data line comprising a pair of sub-lines disposed in every two sub-pixels

    Abstract translation: 本发明示出了面内切换模式LCD及其制造方法,其基本上消除了由于现有技术的限制和缺点而引​​起的一个或多个问题。 为了实现本发明的目的,根据本发明的具有排列成矩阵的多个像素的面内切换模式LCD包括形成在下基板上的栅极线,形成为使得数据线相交的数据线 用于限定像素区域的栅极线,形成在栅极线和数据线的交叉点处的TFT(薄膜晶体管),连接到TFT的像素电极,公共电极以与像素电极产生水平电场 以及向公共电极提供公共电压的公共线,其中所述公共线包括在所述像素区域的下部平行于所述栅极线形成的第一公共线,与所述像素区域的所述日期线平行的第二公共线 与数据线相邻的像素区域的部分,以及与像素区域的上部的栅极线平行地形成的第三公共线,并且其中数据线包括面对d的一对子线 在每两个像素区域中彼此直接相连。 如上所述,本发明具有通过包括设置在每两个子像素中的一对子线的数据线增加孔径比的效果

    Liquid crystal display device comprising one pair of thin film transistors per pixel and method for fabricating the same
    14.
    发明授权
    Liquid crystal display device comprising one pair of thin film transistors per pixel and method for fabricating the same 有权
    每像素包括一对薄膜晶体管的液晶显示装置及其制造方法

    公开(公告)号:US07432995B2

    公开(公告)日:2008-10-07

    申请号:US10875294

    申请日:2004-06-25

    Abstract: A liquid crystal display device having thin film transistors arranged in a zigzag pattern at opposite sides of a gate line, and method for fabricating the same to prevent occurrence of a Cgd variation, even when gate lines or data lines are misaligned in Y- or Z-axis direction, and a defective interface caused by stitching. The device includes a plurality of gate lines arranged on a substrate in one direction, a plurality of data lines substantially perpendicular to the gate lines to define pixel regions, and one pair of thin film transistors per pixel region, the pair of thin film transistors including one pair of first and second gate electrodes projected from the gate lines, a drain electrode substantially parallel to the gate lines, having opposite ends overlapping the first and second gate electrodes, and a source electrode projected from the data lines so as to be adjacent to the opposite ends of the drain electrode and overlap the first and second gate electrodes.

    Abstract translation: 具有在栅极线的相对侧以Z字形排列的薄膜晶体管的液晶显示装置及其制造方法,以防止Cgd变化的发生,即使栅极线或数据线在Y或Z偏移 轴方向,以及由缝合引起的缺陷接口。 该器件包括沿一个方向布置在衬底上的多条栅极线,基本上垂直于栅极线限定像素区域的多条数据线,以及每像素区域一对薄膜晶体管,该对薄膜晶体管包括 从栅极线突出的一对第一和第二栅极电极,基本上平行于栅极线的漏电极,具有与第一和第二栅电极重叠的相对端,以及从数据线突出的源电极,以便与 漏电极的相对端并且与第一和第二栅电极重叠。

    PREDICTION OF AN AGENT'S OR AGENTS' ACTIVITY ACROSS DIFFERENT CELLS AND TISSUE TYPES
    15.
    发明申请
    PREDICTION OF AN AGENT'S OR AGENTS' ACTIVITY ACROSS DIFFERENT CELLS AND TISSUE TYPES 审中-公开
    通过不同细胞和组织类型预测代理或代理活动

    公开(公告)号:US20080118576A1

    公开(公告)日:2008-05-22

    申请号:US11846340

    申请日:2007-08-28

    Abstract: The present invention relates to a novel algorithm that uses molecular profile signatures to extrapolate the physiological processes of one type of cell set (e.g., cell line, tissue, normal or diseased) to predict the activity of an agent or agents against another type of cell set that has never been exposed to the agent in question (drug efficacy prediction). The novel algorithm also allows one to predict the therapeutic response of a patient to a therapeutic regimen even though the patient (or patients) may have never been exposed to that agent before, thereby allowing for selecting a therapeutic agent or combination of agents that would best suit the patient (i.e., personalized medicine). The present invention also relates to methods of using the agents identified by the novel algorithm to treat a variety of diseases, including cancer.

    Abstract translation: 本发明涉及一种使用分子轮廓特征推断一种类型的细胞集(例如,细胞系,组织,正常或患病)的生理过程以预测试剂或试剂对另一类型细胞的活性的新算法 设定从未暴露于有关药物(药物效力预测)。 即使患者(或患者)可能从未暴露于该药物,从而允许选择最佳的治疗剂或药物组合,该新颖算法还允许人们预测患者对治疗方案的治疗反应 适合患者(即个性化医学)。 本发明还涉及使用由新算法鉴定的药物来治疗各种疾病(包括癌症)的方法。

    Array substrate for in-plane switching mode liquid crystal display device and method for fabricating the same
    16.
    发明授权
    Array substrate for in-plane switching mode liquid crystal display device and method for fabricating the same 有权
    用于面内切换模式液晶显示装置的阵列基板及其制造方法

    公开(公告)号:US07116393B2

    公开(公告)日:2006-10-03

    申请号:US10442947

    申请日:2003-05-22

    Applicant: Jae-Kyun Lee

    Inventor: Jae-Kyun Lee

    CPC classification number: G02F1/134363 G02F2001/136218 G02F2001/136263

    Abstract: An array substrate device for a liquid crystal display device includes a substrate, a gate line extending along a first direction on the substrate, a data line extending along a second direction substantially perpendicular to the first direction on the substrate, a pixel region defined by a crossing of the gate and data lines, a common line extending along the first direction and spaced apart from the gate line, a common electrode having a plurality of first portions extended along the second direction from the common line to the pixel region, wherein the extended portion of the common electrode adjacent to the data line includes first and second extensions overlapping portions of the data line, a thin film transistor on the substrate at a crossing portion of the gate and data lines, the thin film transistor including source and drain electrodes, a pixel electrode extended from the drain electrode to the pixel region, and an auxiliary electrode connected to the extended portion of the common electrode adjacent to the data line.

    Abstract translation: 一种液晶显示装置的阵列基板装置,包括基板,沿基板的第一方向延伸的栅极线,沿着与基板的第一方向大致垂直的第二方向延伸的数据线,由 栅极和数据线的交叉,沿着第一方向延伸并与栅极线间隔开的公共线,具有沿着第二方向从公共线延伸到像素区域的多个第一部分的公共电极,其中延伸的 与数据线相邻的公共电极的部分包括数据线的重叠部分的第一和第二延伸部分,栅极和数据线的交叉部分处的衬底上的薄膜晶体管,包括源极和漏极的薄膜晶体管, 从漏电极延伸到像素区域的像素电极,以及连接到该延伸部分的辅助电极 公共电极与数据线相邻。

    Method of fabricating thin film transistor
    17.
    发明授权
    Method of fabricating thin film transistor 有权
    制造薄膜晶体管的方法

    公开(公告)号:US06605494B1

    公开(公告)日:2003-08-12

    申请号:US09598649

    申请日:2000-06-22

    CPC classification number: H01L29/66765 H01L29/78618

    Abstract: In the method of fabricating a TFT in accordance with the present invention, a first semiconductor layer 37 to be used as a channel is formed on a portion of an insulating layer 35 in correspondence with an underlying gate electrode 33. A second semiconductor layer 34, ohmic contact layer 41 and metal layer 45 are then successively formed on the insulating layer 35 and first semiconductor layer 37. A photoresist pattern is next formed on a portion of the ohmic contact layer other than a portion corresponding to the gate electrode. The metal layer is patterned using the photoresist pattern to form source 43 and drain 45 electrodes, and the ohmic contact layer 41 and second semiconductor layer 39 are removed using the photoresist pattern as a mask, or using the source and drain electrodes as a mask, to expose portions of the insulating layer and first semiconductor layer. A passivation layer 47 is formed to cover the insulating layer, first semiconductor layer, and source and drain electrodes. A contact hole 49 is formed in the passivation layer, followed by formation of a pixel electrode 51 in electrical contact with the drain electrode through the contact hole.

    Abstract translation: 在根据本发明的TFT的制造方法中,用作沟道的第一半导体层37形成在与下面的栅电极33对应的绝缘层35的一部分上。第二半导体层34, 然后在绝缘层35和第一半导体层37上依次形成欧姆接触层41和金属层45.接着,在欧姆接触层的与栅电极对应的部分以外的部分上形成光刻胶图形。 使用光致抗蚀剂图案对金属层进行图案化以形成源极43和漏极45电极,并且使用光致抗蚀剂图案作为掩模或者使用源极和漏极作为掩模来去除欧姆接触层41和第二半导体层39, 以暴露绝缘层和第一半导体层的部分。 形成钝化层47以覆盖绝缘层,第一半导体层以及源极和漏极。 在钝化层中形成接触孔49,随后形成通过接触孔与漏电极电接触的像素电极51。

    Hybrid switching mode liquid crystal display device and method of manufacturing thereof
    18.
    发明授权
    Hybrid switching mode liquid crystal display device and method of manufacturing thereof 有权
    混合开关模式液晶显示装置及其制造方法

    公开(公告)号:US06509939B1

    公开(公告)日:2003-01-21

    申请号:US09348704

    申请日:1999-07-07

    CPC classification number: G02F1/134363 G02F2001/134381

    Abstract: A hybrid switching mode liquid crystal display device according to the present invention comprises first and second substrates, a gate bus line and a transparent data bus line defining unit pixel region, a common line parallel to a gate bus line in the pixel region, a TFT on the cross of a data bus line and the gate bus lines in the pixel region, a common electrode and a storage capacitor line in the pixel region, a gate insulator having holes on the gate bus line, the common electrode, and the storage capacitor lines, a passivation layer having holes on the gate insulator, a first alignment layer with a fixed alignment direction on the passivation layer, at least one counter electrode on the second substrate applying vertical and inclined electric fields with the common and data electrodes on the first substrate, a black matrix on the counter electrodes to prevent light leakage which may be generated around TFT, the gate bus lines, and the data bus lines, a color filter layer on the black matrix and the second substrate, a second alignment layer on the color filter layer, and a liquid crystal layer between the first and second substrates.

    Abstract translation: 根据本发明的混合开关模式液晶显示装置包括第一和第二基板,栅极总线和限定单位像素区域的透明数据总线线,与像素区域中的栅极总线平行的公共线,TFT 在像素区域的数据总线和栅极总线的交叉处,像素区域中的公共电极和辅助电容线,在栅极总线,公共电极和存储电容器上具有孔的栅极绝缘体 线路,在栅极绝缘体上具有孔的钝化层,在钝化层上具有固定的取向方向的第一取向层,第二衬底上的至少一个对电极施加垂直和倾斜的电场,其中公共和数据电极在第一 基板,相对电极上的黑矩阵,以防止可能在TFT周围产生的漏光,栅极总线和数据总线,b上的滤色器层 缺少矩阵和第二基板,滤色器层上的第二取向层,以及第一和第二基板之间的液晶层。

    Thin film transistor type photo sensor
    19.
    发明授权
    Thin film transistor type photo sensor 有权
    薄膜晶体管型光电传感器

    公开(公告)号:US06242769B1

    公开(公告)日:2001-06-05

    申请号:US09453299

    申请日:1999-12-03

    CPC classification number: H01L27/14678 H01L29/78633

    Abstract: A TFT type optical detecting sensor includes a sensor TFT for generating optical current by detecting light reflected from an object, a storage capacitor for storing charges of the optical current, and a switching TFT for controlling releasing of the charges stored in the storage capacitor. The storage capacitor is made of a transparent conductive material, such that light is transmitted from a light source through the storage capacitor to the object.

    Abstract translation: TFT型光检测传感器包括用于通过检测从物体反射的光产生光电流的传感器TFT,用于存储光电流的电荷的存储电容器,以及用于控制存储在存储电容器中的电荷释放的开关TFT。 存储电容器由透明导电材料制成,使得光从光源通过存储电容器传输到物体。

    Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof
    20.
    发明授权
    Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof 有权
    顺-2,6-二取代四氢吡喃衍生物及其制备方法

    公开(公告)号:US08115019B2

    公开(公告)日:2012-02-14

    申请号:US12243244

    申请日:2008-10-01

    CPC classification number: C07D309/06

    Abstract: Disclosed are cis-2,6-disubstituted tetrahydropyran derivatives represented by Chemical Formula 1 and a preparation method thereof. The tetrahydropyran derivatives can be prepared by Prins-reacting tetrahydropyran derivatives with homopargylicalcohol derivatives in the presence of trimethylsilyltriflate. The tetrahydropyran derivatives with cis-substituents at both C2 and C6 positions of the tetrahydropyran ring are useful as intermediates for use in the synthesis and development of therapeutically effective, naturally occurring compounds. (wherein, R1, R2 and R3 are as defined in the specification.).

    Abstract translation: 公开了由化学式1表示的顺式-2,6-二取代四氢吡喃衍生物及其制备方法。 四氢吡喃衍生物可以通过Prins-在三甲基甲硅烷基三氟甲磺酸酯存在下将四氢吡喃衍生物与高官能醇衍生物反应来制备。 在四氢吡喃环的C2和C6位上具有顺式取代基的四氢​​吡喃衍生物可用作合成和开发治疗有效的天然存在的化合物的中间体。 (其中,R1,R2和R3如说明书中所定义)。

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