公开(公告)号：US3746161A

公开(公告)日：1973-07-17

申请号：US3746161D

申请日：1971-06-04

Applicant: MILES LAB

Inventor： JONES W

IPC: G02B21/34 ,  B01L9/00 ,  B65D1/36 ,  B65D1/34

CPC classification number: B01L9/52 ,  B01L2300/0822 ,  B65D1/36 ,  Y10S206/804

Abstract: A tray-like holder for flat rectangular objects, such as microscope slides, into which such objects can be easily placed and from which such objects can be easily withdrawn comprises a base with upstanding elongated sidewalls and transverse endwalls to form a major elongated receptacle. This major receptacle is divided into individual smaller receptacles by a plurality of vertical partitions which extend transversely inwardly from each of the longitudinal sidewalls. Between adjacent partitions there is located an abutment on or adjacent to the corresponding longitudinal sidewall. A row of openings in the base is located adjacent and generally parallel with at least one of the longitudinal sidewalls, each of the openings being located between adjacent transverse partitions. An object can be easily placed on the base between adjacent partitions with one end of the object engaging an abutment and the other end of the object extending partially over a corresponding opening in the base. The object can be easily removed by placing a finger into the base opening against the exposed end of the object and lifting the object.

Abstract translation: 用于扁平矩形物体（例如显微镜载玻片）的托盘状保持器，可容易地放置这些物体并使该物体容易地从中收放包括具有直立的细长侧壁和横向端壁的底座，以形成主细长插座。 该主要容器通过多个从每个纵向侧壁横向向内延伸的垂直隔板分成多个较小的容器。 在相邻隔板之间，在对应的纵向侧壁上或邻近相应的纵向侧壁上设置有邻接件。 基座中的一排开口位于相邻并且大致平行于至少一个纵向侧壁，每个开口位于相邻的横向隔板之间。 物体可以容易地放置在相邻隔板之间的基部上，物体的一端与基座接合，物体的另一端部分地延伸在基座中的相应开口上。 通过将手指放置在基部开口中抵靠物体的暴露端并抬起物体，可以容易地去除物体。

公开(公告)号：US3697730A

公开(公告)日：1972-10-10

申请号：US3697730D

申请日：1971-02-26

Applicant: MILES LAB

Inventor： CLACK PETER JOSEPH ,  WISWELL JAMES DAVID ,  CLEMENS ANTON HUBERT

IPC: G06M1/10 ,  G06M3/08

CPC classification number: G06M3/08 ,  G06M1/101

Abstract: Apparatus to produce data count signals in a form equivalent to C/n + OR - C'', wherein n is a variable and C and C'' are constants is described comprising a source of an initiating signal, a source of a terminating signal, a first time-base generator, a first gated digital/analog convertor, an amplifier, a second time-base generator, a gated counter and a circuit component for adding or subtracting a desired number of pulses to the gated counter. The two signal sources, the first time-base generator, and the first convertor are connected so that the pulses accumulated in the first convertor between the initiating signal and the terminating signal are directly proportional to n. The amplifier is connected between the first and second convertors so as to apply an amplified reference signal to the second convertor which is directly proportional to n. The two signal sources, the second time-base generator, the second convertor, the counter and the comparator are connected so as to produce an output signal in the counter directly proportional to C/n. The component for adding or subtracting pulses is connected to the counter so that the counter output is directly proportional to C/n + OR - C''. This apparatus is especially useful to measure specific gravity of liquids by the falling drop method.

Abstract translation: 用于以等同于C / n +/- C'的形式产生数据计数信号的装置，其中n是变量，C和C'是常数，其包括起始信号的源，终止信号的源， 第一时基生成器，第一门控数字/模拟转换器，放大器，第二时基发生器，门控计数器和用于将所需数量的脉冲添加或减去门控计数器的电路组件。 两个信号源，第一时基发生器和第一转换器被连接，使得在起始信号和终止信号之间积累在第一转换器中的脉冲与n成正比。 放大器连接在第一和第二转换器之间，以将放大的参考信号施加到与n成正比的第二转换器。 连接两个信号源，第二时基发生器，第二转换器，计数器和比较器，以便在与C / n成正比的计数器中产生输出信号。 用于增加或减少脉冲的组件连接到计数器，使得计数器输出与C / n +/- C'成正比。 该装置特别适用于通过落滴法测量液体的比重。

公开(公告)号：US3684451A

公开(公告)日：1972-08-15

申请号：US3684451D

申请日：1969-08-20

Applicant: MILES LAB

Inventor： LINOLI GIANNI ,  MANNUCCI ENZO SERGIO

IPC: C08F8/30 ,  C12Q1/34 ,  C12Q1/42 ,  C12Q1/44 ,  C12Q1/52 ,  G01N33/52 ,  C07G7/02 ,  C08F27/08 ,  G01N31/00

CPC classification number: C12Q1/52 ,  C08F8/30 ,  C12Q1/34 ,  C12Q1/42 ,  C12Q1/44 ,  C12Q2334/30 ,  C12Q2334/70 ,  G01N33/52 ,  Y10S435/805 ,  Y10S435/814 ,  Y10T436/173845 ,  Y10T436/203332

Abstract: A NOVEL INSOLUBLE POLYMERIC DIAZONIUM SALT COLOR DEVELOPER CONSISTING OF A DIAZOTIZED AROMATIC POLYAMINE BOUND BY AN AMIDE LINKAGE TO A CATION EXCHANGE RESIN CAN BE PREPARED BY REACTING A CATION EXCHANGE RESIN CONTAINING ACID GROUPS WITH A HALOGENATING AGENT TO CONVERT SOME OF THE RESIN ACID GROUPS TO ACYL HALIDE GROUPS, REACTING THE RESULTING ACYL HALIDE GROUPS WITH AN AROMATIC POLYAMINE TO FORM A RESIN CONTAINING AMIDE LINKAGES AND FREE AROMATIC AMINO GROUPS, AND THEN DIAZOTIZING THE FREE AROMATIC AMINO GROUPS. THE RESULTING INSOLUBLE COLOR DEVELOPER CAN BE USED TO DETECT COUPLING COMPOUNDS BY FORMING COLORED REACTION PRODUCTS WITH SUCH COUPLING COMPOUNDS. THE COLOR DEVELOPER CAN ALSO BE USED TO DETECT AN ENZYME SYSTEM WHEREIN THE ENZYME CATALYZES A REACTION WITH A SUITABLE SUBSTRATE TO RELEASE A COUPLING COMPOUND WHICH WILL FORM A COLORED REACTION PRODUCT WITH THE INSOLUBLE COLOR DEVELOPER.

公开(公告)号：US3667896A

公开(公告)日：1972-06-06

申请号：US3667896D

申请日：1968-10-21

Applicant: MILES LAB

Inventor： MCCORMICK JAMES BENJAMIN ,  JOHNSON LEIGHTON CLIFFORD

IPC: G01N1/31 ,  G02B21/34 ,  D06P3/00

CPC classification number: G02B21/34 ,  G01N1/312

Abstract: APPARATUS AND THE METHOD OF OPERATION THEREOF IS DESCRIBED FOR CONVEYING OBJECTS, SUCH AS MICROSCOPE SLIDES, OVER A FLAT LIQUID APPLYING SURFACE AND INJECTING A TREATING LIQUID INTO THE SPACE BETWEEN THE OBJECT AND THE SURFACE.

公开(公告)号：US3661716A

公开(公告)日：1972-05-09

申请号：US3661716D

申请日：1969-08-08

Applicant: MILES LAB

Inventor： FUKUMOTO JUICHIRO ,  YAMAMOTO TAKEHIKO

IPC: C12N9/22 ,  C12N9/30 ,  C12N9/34 ,  C12N9/58 ,  C07G7/02

CPC classification number: C12N9/242 ,  C12N9/22 ,  C12N9/2428 ,  C12N9/58 ,  Y10S435/939

Abstract: Purified fractions of protease and ribonuclease produced from a Rhizopus mold can be obtained by contacting a solution containing protease and ribonuclease with a cation-exchange material to selectively adsorb the ribonuclease. The purified protease fraction is then separated from the cation-exchange material. A purified ribonuclease fraction is then removed by elution, for example, from the cation-exchange material. The initial protease and ribonuclease-containing solution is preferably purified to remove amyloglucosidase and amylase prior to being separated into protease and ribonuclease fractions.

Abstract translation: 通过将含有蛋白酶和核糖核酸酶的溶液与阳离子交换材料接触以选择性吸附核糖核酸酶，可以获得从根霉霉菌产生的蛋白酶和核糖核酸酶的纯化级分。 然后将纯化的蛋白酶级分与阳离子交换材料分离。 然后通过例如从阳离子交换材料洗脱除去纯化的核糖核酸酶级分。 初始的蛋白酶和含核糖核酸酶的溶液优选在被分离成蛋白酶和核糖核酸酶级分之前被纯化以除去淀粉葡萄糖苷酶和淀粉酶。

公开(公告)号：US3655526A

公开(公告)日：1972-04-11

申请号：US3655526D

申请日：1969-11-20

Applicant: MILES LAB

Inventor： CHRISTIAN GARY DALE

IPC: G01N27/413 ,  G01N27/416 ,  G01N31/16 ,  G01N27/40 ,  G01N27/46

CPC classification number: G01N31/164

Abstract: Potentiometric titration of a wide variety of reagents in solution can be conducted using an ion selective sensing device including a standard reference electrode, a reference electrolyte and a semipermeable polymeric membrane which separates the reference electrolyte from the solution containing the ion being titrated. The semipermeable polymeric membrane contains an ester of phthalic or isophthalic acid which serves to discriminate between the ion being titrated and other ions in the medium.

Abstract translation: 溶液中各种试剂的电位滴定可以使用包括标准参比电极，参考电解质和将包含待滴定离子的溶液分离参比电解质的半透膜聚合物膜的离子选择性感测装置进行。 半透性聚合物膜含有邻苯二甲酸或间苯二甲酸的酯，其用于区分待滴定的离子和介质中的其它离子。

公开(公告)号：US3655513A

公开(公告)日：1972-04-11

申请号：US3655513D

申请日：1971-01-25

Applicant: MILES LAB

Inventor： STERNBERG MOSHE

IPC: C12N9/50 ,  C07G7/02

CPC classification number: C12N9/50 ,  Y10S435/814 ,  Y10S435/839

Abstract: Proteases can be isolated and separated from impurities, such as colored bodies, sugars, polysaccharides and minerals, by mixing a protease solution containing impurities with a heteropoly acid to form a precipitate with the protease. The resulting precipitate is then separated from the remaining solution and dried. Useful heteropoly acids are phosphotungstic acid, arsenotungstic acid, silicotungstic acid, borotungstic acid, phosphomolybdic acid, arsenomolybdic acid, silicomolybdic acid, boromolybdic acid, phosphovanadic acid, arsenomolybdic acid, silicovanadic acid, borovanadic acid and mixtures and combinations thereof.

Abstract translation: 通过将含有杂质的蛋白酶溶液与杂多酸混合以与蛋白酶形成沉淀物，可以将蛋白酶分离并与杂质（例如着色体，糖，多糖和矿物质）分离。 然后将所得沉淀物与剩余的溶液分离并干燥。 有用的杂多酸是磷钨酸，砷钨酸，硅钨酸，硼钨酸，磷钼酸，砷钼酸，硅钼酸，硼钼酸，磷酸钒酸，砷钼酸，硅钒酸，硼钒酸，以及它们的混合物和组合。

公开(公告)号：US3653931A

公开(公告)日：1972-04-04

申请号：US3653931D

申请日：1970-12-30

Applicant: MILES LAB

Inventor： BORCHERT PETER JOCHEN ,  SLAGER JAMES EDWARD ,  SOMMER RONALD GEORGE ,  ZIENTY MITCHELL FRANK

IPC: C23F11/08 ,  C09G1/14

CPC classification number: C23F11/08

Abstract: The clean surface of metals, such as copper and coppercontaining alloys, can be protected from tarnishing by a composition containing a mixture of a surfactant, benzotriazole, sodium bisulfite and ethylenediaminetetraacetic acid. This composition is generally mixed with water and the clean metal surface is dipped in or otherwise contacted with the aqueous solution.

Abstract translation: 可以通过含有表面活性剂，苯并三唑，亚硫酸氢钠和乙二胺四乙酸的混合物的组合物来保护金属的清洁表面，例如铜和含铜合金。 该组合物通常与水混合，并将清洁的金属表面浸入或以其他方式与水溶液接触。

公开(公告)号：US3635986A

公开(公告)日：1972-01-18

申请号：US3635986D

申请日：1969-12-22

Applicant: MILES LAB

Inventor： DYKE JOHN WILLIAM VAN JR

IPC: C07D39/00

Abstract: 2-SUBSTITUTED AMINO-HEXAHYDROBENZO(A)QUINOLIZINES AND PHARMACOLOGICALLY ACEPTABEL SALTS THEREOF THAT ARE USEFUL AS ANTI-HYPERTENSIVE AGENTS. PREPARED BY REACTING 2-OXO1,3,4,6,7,11B-HEXAHYDRO -2H -BENZO(A) QUINOLIZINE WITH AN AMINO TO FORM A SCHIFF BASE WHICH IS THEN REDUCED.

公开(公告)号：US3634195A

公开(公告)日：1972-01-11

申请号：US3634195D

申请日：1969-09-08

Applicant: MILES LAB

Inventor： MELACHOURIS NICHOLAS ,  CHARLES ROBERT LEMOYNE

IPC: C12N9/20 ,  C12D13/06

CPC classification number: C12N9/20 ,  Y10S435/912

Abstract: A lipase enzyme which hydrolyzes glycerides of long-chain carboxylic acids in preference to those of short-chain carboxylic acids can be produced by growing under aerobic conditions a culture of a strain of Absidia in a medium containing appropriate nutrients and then recovering the enzyme therefrom. An especially useful strain is Absidia butleri.

Abstract translation: 通过在需氧条件下，在含有适当营养物质的培养基中培养茜草属的培养物，然后从其中回收酶，可以产生优选长链羧酸甘油酯优于短链羧酸的脂肪酶。 一种特别有用的菌株是耻垢is虫（Absidia butleri）。