公开(公告)号：US20100119920A1

公开(公告)日：2010-05-13

申请号：US12649945

申请日：2009-12-30

Applicant: Bruce Logan ,  Douglas Call ,  Matthew Merrill ,  Shaoan Cheng

Inventor： Bruce Logan ,  Douglas Call ,  Matthew Merrill ,  Shaoan Cheng

IPC: C25B1/04 ,  C25B9/00 ,  C25B11/04 ,  B05D5/00

CPC classification number: H01M4/8605 ,  H01M4/8657 ,  H01M4/8853 ,  H01M4/9008 ,  H01M4/9016 ,  H01M4/92 ,  H01M8/16 ,  H01M2004/8689 ,  Y02E60/366 ,  Y02E60/527

Abstract: An apparatus is provided according to embodiments of the present invention which includes a reaction chamber having a wall defining an interior of the reaction chamber and an exterior of the reaction chamber; exoelectrogenic bacteria disposed in the interior of the reaction chamber; an aqueous medium having a pH in the range of 3-9, inclusive, the aqueous medium including an organic substrate oxidizable by exoelectrogenic bacteria and the medium disposed in the interior of the reaction chamber. An inventive apparatus further includes an anode at least partially contained within the interior of the reaction chamber; and a brush or mesh cathode including stainless steel, nickel or titanium, the cathode at least partially contained within the interior of the reaction chamber.

Abstract translation: 根据本发明的实施例提供了一种装置，其包括具有限定反应室内部的壁和反应室外部的反应室; 设置在反应室内部的外电子细菌; pH在3-9范围内的水性介质，所述水性介质包括可由外生电位细菌可氧化的有机底物和设置在反应室内部的介质。 本发明的设备还包括至少部分地包含在反应室内部的阳极; 以及包括不锈钢，镍或钛的刷子或网状阴极，阴极至少部分地包含在反应室的内部。

公开(公告)号：US06867230B2

公开(公告)日：2005-03-15

申请号：US09872731

申请日：2001-06-01

Applicant: Matthew Merrill Hayward ,  Michael S. Visser ,  Robert G. Linde, II ,  Takushi Kaneko

Inventor： Matthew Merrill Hayward ,  Michael S. Visser ,  Robert G. Linde, II ,  Takushi Kaneko

IPC: A61K31/357 ,  A61K31/443 ,  A61K31/70 ,  A61K31/7004 ,  A61K31/7034 ,  A61P31/04 ,  A61P31/10 ,  A61P33/02 ,  C07D405/12 ,  C07D405/14 ,  C07D407/12 ,  C07D407/14 ,  C07D453/02 ,  C07D487/08 ,  C07D521/00 ,  C07H15/203 ,  A61K31/36 ,  C07D317/66

CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D405/14 ,  C07D407/12 ,  C07D407/14 ,  C07D453/02 ,  C07D487/08 ,  C07H15/203

Abstract: This invention relates to compounds of the formula and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3 and R10 are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1, methods of treating bacterial and protozoal infections by administering the compounds of formula 1.

Abstract translation: 本发明涉及式的化合物及其药学上可接受的盐，前药和溶剂合物，其中R 1，R 2，R 3和R 10如本文所定义。 式1的化合物是可用于治疗各种细菌和原生动物感染的抗细菌剂和抗原虫药，以及与这种感染有关的疾病。 本发明还涉及含有式1化合物的药物组合物，通过施用式1化合物来治疗细菌和原生动物感染的方法。