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公开(公告)号：US06649369B2
公开(公告)日：2003-11-18
申请号：US10118010
申请日：2002-04-09
IPC分类号： C12P3500
摘要： The present invention relates to a process for delaying the deactivation of glutaryl amidase during enzyme catalysis. The enzyme catalyst is, after maximum conversion of the substrate, separated off by filtration and can be reused in a subsequent reaction batch. In each reaction cycle, the enzyme catalyst loses activity. The inactivation of the enzyme catalyst can be delayed by bringing it into contact with a thiol during the reaction.
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公开(公告)号：US5830743A
公开(公告)日：1998-11-03
申请号：US312675
申请日：1994-09-28
CPC分类号： C12N9/80
摘要： The gene encoding glutarylacylase (GA) contained in the plasmid pCM 145 (DSM 6409) permits the expression of GA in E. coli in high yields.
摘要翻译： 质粒pCM 145（DSM 6409）中所含的编码戊二酰基化酶（GA）的基因允许以高产率在大肠杆菌中表达GA。
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13.发明授权
公开(公告)号：US5766881A
公开(公告)日：1998-06-16
申请号：US544087
申请日：1995-10-17
申请人： Werner Aretz , Ulrich Holst , Klaus Peter Koller
发明人： Werner Aretz , Ulrich Holst , Klaus Peter Koller
IPC分类号： C12N15/09 , C07H21/04 , C12N9/80 , C12N15/31 , C12N15/72 , C12R1/19 , C12P21/02 , C12N15/56 , C12N15/70
摘要： Improved, induction-free process for the recombinant preparation of glutarylamidase. The invention relates to a recombinant process for preparing glutarylamidase (GA), wherein the GA gene is expressed constitutively from an expression vector. In certain embodiments, the promoter for constitutively expressing the GA gene is a trc promoter or a trc-equivalent promoter which does not have any repressor or has a non-functional repressor.
摘要翻译： 改进的无诱导的戊二酰胺酶重组制备方法。 本发明涉及一种制备戊二酰胺酶（GA）的重组方法，其中GA基因从表达载体中组成型表达。 在某些实施方案中，用于组成型表达GA基因的启动子是不具有任何阻遏物或具有非功能性阻遏物的trc启动子或trc等效启动子。
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14.发明授权Clostripain catalyzed hydrolysis of preproinsulin analogs into corresponding insulins 失效梭菌素催化前胰岛素类似物水解成相应的胰岛素
公开(公告)号：US5728543A
公开(公告)日：1998-03-17
申请号：US291060
申请日：1994-08-08
摘要： A process is described to specifically hydrolyze the amino acid chain of preproinsulin analogs to give the corresponding insulins. The hydrolysis is catalyzed by clostripain and, if necessary, carboxypeptidase B.
摘要翻译： 描述了一种方法来特异性水解前胰岛素类似物的氨基酸链，得到相应的胰岛素。 水解由clostripain催化，如果需要，羧肽酶B.
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公开(公告)号：US1426482A
公开(公告)日：1922-08-22
申请号：US46763021
申请日：1921-05-07
申请人： PETER KOLLER JOSEPH
发明人： PETER KOLLER JOSEPH
IPC分类号： A63H33/00
CPC分类号： A63H33/00
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公开(公告)号：US20170011896A1
公开(公告)日：2017-01-12
申请号：US14902491
申请日：2014-07-01
申请人： Peter KOLLER
发明人： Peter KOLLER
摘要： A detector plate includes a carrier plate, especially an injection-molded carrier plate, having a plurality of detector elements for detecting ionizing radiation. The detector elements function according to the principle of a Geiger-Müller counter. To simplify the production process and to save cost, the anode and/or the cathode should be in the form of a metallization on the carrier plate of the detector plate, the metallization(s) not being present in a single plane only. This configuration offers multiple options for designing the interior used as ionization chamber and for arranging the electrodes in this space. The options for contact with additional printed circuit boards also turn out to be highly advantageous. This further has an advantageous effect on the production process and on the qualities of the radiation measurement devices using detector plates of this kind.
摘要翻译： 检测器板包括具有用于检测电离辐射的多个检测器元件的承载板，特别是注射成型载体板。 检测器元件根据Geiger-Müller计数器的原理起作用。 为了简化生产过程并节省成本，阳极和/或阴极应当是在检测器板的载体板上的金属化形式，金属化不仅存在于单个平面中。 该配置提供了用于设计用作电离室的内部和用于将电极布置在该空间中的多种选择。 与附加印刷电路板接触的选项也是非常有利的。 这对于使用这种检测器板的生产过程和辐射测量装置的质量进一步有益。
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17.发明授权Gas-monitoring assembly comprising one or more gas sensors and one or more getters, and method of using same 有权包括一个或多个气体传感器和一个或多个吸气剂的气体监测组件及其使用方法公开(公告)号：US08840766B2
公开(公告)日：2014-09-23
申请号：US13454616
申请日：2012-04-24
申请人： Stefan Stromereder , Peter Koller
发明人： Stefan Stromereder , Peter Koller
IPC分类号： G01N27/403 , G01J1/50
CPC分类号： G01N33/0031
摘要： The present invention relates to a gas-monitoring assembly (100) and method for selectively determining the presence of a target gas in a gaseous environment that potentially comprises one or more interfering gases. Such gas-monitoring assembly and method specifically employ one or more gas sensors (S1) one or more getters (G1) arranged and constructed to reduce cross-interference caused by potential presence of the interfering gases in such gaseous environment to be monitored. The gas-monitoring assembly and method of the present invention are capable of monitoring a gaseous environment with respect to potential presence of multiple target gases that may interfere with one another.
摘要翻译： 本发明涉及一种气体监测组件（100）和用于选择性地确定气体环境中潜在地包含一种或多种干扰气体的目标气体的存在的方法。 这种气体监测组件和方法特别地使用一个或多个气体传感器（S1）布置和构造一个或多个吸气剂（G1），以减少在待监测的气体环境中潜在的干扰气体存在引起的交叉干扰。 本发明的气体监测组件和方法能够监测相对于可能彼此干扰的多种目标气体的潜在存在的气体环境。
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18.发明申请Gas-monitoring assembly comprising one or more gas sensors and one or more getters, and method of using same 有权包括一个或多个气体传感器和一个或多个吸气剂的气体监测组件及其使用方法公开(公告)号：US20070158210A1
公开(公告)日：2007-07-12
申请号：US11571500
申请日：2005-06-29
申请人： Stefan Stromereder , Peter Koller
发明人： Stefan Stromereder , Peter Koller
IPC分类号： G01N27/26
CPC分类号： G01N33/0031
摘要： The present invention relates to a gas-monitoring assembly (100) and method for selectively determining the presence of a target gas in a gaseous environment that potentially comprises one or more interfering gases. Such gas-monitoring assembly and method specifically employ one or more gas sensors (S1) one or more getters (G1) arranged and constructed to reduce cross-interference caused by potential presence of the interfering gases in such gaseous environment to be monitored. The gas-monitoring assembly and method of the present invention are capable of monitoring a gaseous environment with respect to potential presence of multiple target gases that may interfere with one another.
摘要翻译： 本发明涉及一种气体监测组件（100）和用于选择性地确定气体环境中潜在地包含一种或多种干扰气体的目标气体的存在的方法。 这种气体监测组件和方法具体采用一个或多个气体传感器（S1）一个或多个排气和构造的吸气剂（G 1），以减少在待监测的气体环境中由干扰气体的潜在存在引起的交叉干扰。 本发明的气体监测组件和方法能够监测相对于可能彼此干扰的多种目标气体的潜在存在的气体环境。
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19.发明授权Gas-monitoring assembly comprising one or more gas sensors and one or more getters, and method of using same 有权包括一个或多个气体传感器和一个或多个吸气剂的气体监测组件及其使用方法公开(公告)号：US07140229B2
公开(公告)日：2006-11-28
申请号：US10880248
申请日：2004-06-29
申请人： Stefan Stromereder , Peter Koller
发明人： Stefan Stromereder , Peter Koller
CPC分类号： G01N33/0031
摘要： The present invention relates to a gas-monitoring assembly and method for selectively determining the presence of a target gas in a gaseous environment that potentially comprises one or more interfering gases. Such gas-monitoring assembly and method specifically employ one or more gas sensors one or more getters arranged and constructed to reduce cross-interference caused by potential presence of the interfering gases in such gaseous environment to be monitored. The gas-monitoring assembly and method of the present invention are capable of monitoring a gaseous environment with respect to potential presence of multiple target gases that may interfere with one another.
摘要翻译： 本发明涉及一种气体监测组件和方法，用于选择性地确定潜在地包含一种或多种干扰气体的气体环境中目标气体的存在。 这种气体监测组件和方法具体采用一个或多个气体传感器，一个或多个吸气剂被布置和构造，以减少在待监测的气体环境中由干扰气体的潜在存在所引起的交叉干扰。 本发明的气体监测组件和方法能够监测相对于可能彼此干扰的多种目标气体的潜在存在的气体环境。
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20.发明授权Saccharomyces cerevisiae yeast strain with functional expression of a GLUT transporter gene 有权具有GLUT转运蛋白基因功能性表达的酿酒酵母菌株公开(公告)号：US08574909B2
公开(公告)日：2013-11-05
申请号：US11399990
申请日：2006-04-07
摘要： The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene.
摘要翻译： 本发明涉及酵母酿酒酵母菌株，其由于基因组序列的缺失而不再合成己糖转运蛋白，因此不能再以己糖作为唯一的碳源在底物上生长，并且其能力 生长在具有己糖的底物上，当其表达GLUT4基因时，唯一的碳源被还原。
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