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    MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD
    11.
    发明申请
    MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
    单相电动势电位记录导管及方法

    公开(公告)号：US20110028820A1

    公开(公告)日：2011-02-03

    申请号：US12511707

    申请日：2009-07-29

    申请人： Michael LAU ,  Randell WERNETH ,  Timothy J. CORVI ,  Sumita BHOLA ,  Mark T. STEWART

    发明人： Michael LAU ,  Randell WERNETH ,  Timothy J. CORVI ,  Sumita BHOLA ,  Mark T. STEWART

    IPC分类号： A61B5/04 ,  A61N1/05 ,  A61B18/14

    CPC分类号： A61B5/042 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61N1/06

    摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.

    摘要翻译： 用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。 远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。 记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。 参考电极是与记录几何形状的纵向距离。 可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。 不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

    Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
    12.
    发明申请
    Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device 有权

    公开(公告)号：US20080071337A1

    公开(公告)日：2008-03-20

    申请号：US11983946

    申请日：2007-11-13

    申请人： John Dobak ,  Juan Lasheras ,  Randell Werneth

    发明人： John Dobak ,  Juan Lasheras ,  Randell Werneth

    IPC分类号： A61F7/12 ,  G05D23/00

    CPC分类号： A61B18/02 ,  A61B2017/00292 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F7/12 ,  A61F2007/0056 ,  A61F2007/126 ,  G05D23/1919 ,  G05D23/22 ,  G05D23/24

    摘要： A guidable catheter for heating or cooling a surrounding fluid in a feeding vessel in a vasculature of a patient. The catheter includes a heat transfer element, the heat transfer element having a plurality of exterior surface irregularities shaped and arranged to create turbulence in a surrounding fluid. The surface irregularities have a depth at least equal to the boundary layer thickness of flow of the surrounding fluid in the feeding vessel. The catheter assembly also includes a supply catheter having a portion disposed within the heat transfer element to deliver a working fluid to an interior of the heat transfer element. The catheter assembly further includes a return catheter to return a working fluid from the interior of the heat transfer element. A guidewire tube is provided adjacent one of the supply catheter or the return catheter and runs substantially parallel to the axis of the guidable catheter to receive a guidewire disposed within the guidewire tube. The guidable catheter may further have a temperature-monitoring device disposed at the distal tip of the guidewire. The temperature-monitoring device may be a thermocouple or a thermistor. Feedback may further be provided to control the temperature of a source of working fluid. A method is also provided for selectively controlling the temperature of a selected volume of blood in a patient. The method includes introducing a guidewire into a blood vessel feeding a selected volume of blood in a patient and introducing a catheter assembly into the blood vessel feeding a selected volume of blood in a patient by inserting the guidewire into a guidewire tube in the catheter assembly. A working fluid is delivered from a source of working fluid through a supply catheter in the catheter assembly and returned through a return catheter in the catheter assembly. Heat is transferred between a heat transfer element forming a distal end of the catheter assembly and the volume of blood in the feeding vessel. The temperature is monitored of the volume of blood in the feeding vessel by measuring the temperature with a temperature-monitoring device disposed at or near the distal tip of the guidewire.

    Multipurpose catheter assembly
    16.
    发明授权
    Multipurpose catheter assembly 失效
    多功能导管组件

    公开(公告)号：US06979345B2

    公开(公告)日：2005-12-27

    申请号：US10176895

    申请日：2002-06-20

    申请人： Randell Werneth

    发明人： Randell Werneth

    IPC分类号： A61F7/12 ,  A61F7/00

    CPC分类号： A61F7/12 ,  A61F2007/126

    摘要： An apparatus for performing hypothermia of the body of a patient, or of a selected organ, while delivering a medicament to a selected blood vessel. A flexible coaxial catheter is inserted through the vascular system of a patient to place the distal tip of the catheter in a selected artery. A chilled fluid is pumped through an inner supply conduit of the catheter to cool a flexible heat transfer element in the distal tip of the catheter. The heat transfer element cools the blood flowing through the artery distal to the tip of the catheter. The medicament, such as a vaso-dilator, is delivered either separately or mixed with the chilled fluid, through a very small exit port in or near the heat transfer element.

    摘要翻译： 一种用于在将药物递送至所选择的血管的同时，对患者或选定器官的身体进行体温过低的装置。 将柔性同轴导管穿过患者的血管系统插入导管的远端以选择动脉。 冷冻流体被泵送通过导管的内部供应管道以冷却导管的远侧末端中的柔性传热元件。 传热元件冷却流过导管末端的动脉的血液。 药物，例如血管扩张器，分开地或与冷冻液体混合，通过传热元件内或附近的非常小的出口。

    Inflatable heat transfer apparatus
    17.
    发明授权
    Inflatable heat transfer apparatus 有权

    公开(公告)号：US06676690B2

    公开(公告)日：2004-01-13

    申请号：US09885655

    申请日：2001-06-20

    申请人： Randell Werneth

    发明人： Randell Werneth

    IPC分类号： A61F712

    CPC分类号： A61F7/123 ,  A61F2007/126

    摘要： An apparatus having an inflatable balloon near a distal end of a multi-lumen catheter, with a plurality of blood flow passageways formed through the interior of the balloon from a proximal face of the inflated balloon to a distal face of the inflated balloon. A heat transfer solution is introduced through a supply lumen of the catheter to inflate the balloon in a selected blood vessel; this allows blood to flow through the blood flow passageways of the balloon, from one exterior face of the balloon to another exterior face. The heat transfer solution continues to circulate around the blood flow passageways inside the balloon, to change the blood temperature, eventually exiting the balloon through a return lumen of the catheter.

    Bi-modal catheter steering mechanism
    18.
    发明授权
    Bi-modal catheter steering mechanism 有权
    双向导管转导机制

    公开(公告)号：US09387035B2

    公开(公告)日：2016-07-12

    申请号：US12546796

    申请日：2009-08-25

    申请人： Randell Werneth ,  Ricardo Roman ,  Timothy J. Corvi ,  Betty Hu

    发明人： Randell Werneth ,  Ricardo Roman ,  Timothy J. Corvi ,  Betty Hu

    IPC分类号： A61B18/14 ,  A61B17/00 ,  A61B18/00

    CPC分类号： A61B18/1492 ,  A61B5/042 ,  A61B2017/003 ,  A61B2017/00323 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/1407 ,  A61B2018/1422 ,  A61B2018/1467 ,  A61M25/0147 ,  A61N1/056

    摘要： Medical devices, systems, and methods for treating patients with tissue ablation include catheter systems having bi-modal steering mechanisms, which are capable of both linear and loop ablation. In other words, the catheter system may have two different steering modes: two-dimensional and three-dimensional. In the first and second steering modes, the steering actuator may cause one or more portions of the catheter shaft to bend in different planes. A steerable ablation catheter may include treatment elements such as electrodes at its distal end and along the catheter shaft, each of which may map, pace, and ablate.

    摘要翻译： 用于治疗患有组织消融的患者的医疗装置，系统和方法包括具有双向转向机构的导管系统，其能够进行线性和环路消融。 换句话说，导管系统可以具有两种不同的转向模式：二维和三维。 在第一和第二转向模式中，转向致动器可导致导管轴的一个或多个部分在不同的平面中弯曲。 可引导的消融导管可以包括治疗元件，例如其远端处的电极和沿着导管轴的每个可以映射，步伐和消融的治疗元件。