公开(公告)号：US20120136409A1

公开(公告)日：2012-05-31

申请号：US13330016

申请日：2011-12-19

Applicant: Steven M. Goetz ,  Donald R. Johnson ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Theodore J. Stone ,  Kenneth T. Heruth ,  Gary W. King ,  Roy L. Testerman

Inventor： Steven M. Goetz ,  Donald R. Johnson ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Theodore J. Stone ,  Kenneth T. Heruth ,  Gary W. King ,  Roy L. Testerman

IPC: A61N1/372

CPC classification number: A61N1/37264 ,  A61N1/36071 ,  A61N1/36132 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G16H40/63 ,  G16H50/20

Abstract: Techniques that involve application of one or more rules to a “parent” program to generate a plurality of different “child” programs are described. Each of the rules may define a respective electrode configuration modification, and each child program may be a variation of the parent based on a modification of the electrode configuration of the parent according to one of the rules. The systems or devices may generate further generations of child programs from a previous generation child program using the same one or more rules. The child programs may be provided to a user, so that the user may test the efficacy of the new programs, assisting the user in identifying desirable programs. The child programs may be relatively minor variations of the parent program, and the user may “fine tune” a generally desirable parent program by testing the child programs.

Abstract translation: 描述涉及将一个或多个规则应用于“父”程序以生成多个不同的“子”程序的技术。 每个规则可以限定相应的电极配置修改，并且每个子程序可以是基于根据规则之一的父母的电极配置的修改的父母的变体。 系统或设备可以使用相同的一个或多个规则从上一代子程序生成更多代的子程序。 子程序可以被提供给用户，使得用户可以测试新程序的功效，帮助用户识别期望的程序。 子程序可能是父程序的相对小的变化，并且用户可以通过测试子程序来“微调”通常期望的父程序。

公开(公告)号：US08160328B2

公开(公告)日：2012-04-17

申请号：US12359247

申请日：2009-01-23

Applicant: Steven M. Goetz ,  Wende L. Dewing ,  Andrew Ng

Inventor： Steven M. Goetz ,  Wende L. Dewing ,  Andrew Ng

IPC: G06K9/00

CPC classification number: A61N1/37264 ,  A61N1/0551 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G06T7/0012 ,  G06T7/73 ,  G06T2207/10116 ,  G06T2207/30052 ,  G06T2207/30196

Abstract: In general, the disclosure is related to characterization of implanted electrical stimulation electrode arrays using post-implant imaging. The electrode arrays may be carried by implanted leads. Characterization of implanted electrode arrays may include identification of the type or types of leads implanted within a patient and/or determination of positions of the implanted leads or electrodes carried by the leads relative to one another or relative to anatomical structures within the patient. In addition, the disclosure relates to techniques for specifying or modifying patient therapy parameters based on the characterization of the implanted electrode arrays.

Abstract translation: 通常，本公开涉及使用植入后成像的植入电刺激电极阵列的表征。 电极阵列可以由注入引线携带。 植入电极阵列的表征可以包括识别植入在患者体内的引线的类型或类型，和/或确定由导线相对于彼此或相对于患者内的解剖结构承载的植入引线或电极的位置。 此外，本公开涉及基于植入的电极阵列的表征来指定或修改患者治疗参数的技术。

公开(公告)号：US20110313485A1

公开(公告)日：2011-12-22

申请号：US13220113

申请日：2011-08-29

Applicant: Delight D. DeMulling ,  Debbie A. McConnell ,  Steven M. Goetz ,  Cari C. Herman ,  Wende L. Dewing

Inventor： Delight D. DeMulling ,  Debbie A. McConnell ,  Steven M. Goetz ,  Cari C. Herman ,  Wende L. Dewing

IPC: A61N1/372

CPC classification number: A61N1/372 ,  A61N1/36003 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/36185 ,  A61N1/3688 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37264

Abstract: Techniques that involve generating test stimulation programs based upon specific patient feedback to guide the programming process for stimulation therapy are described. The patient describes positive effects and adverse effects of the test stimulation by listing and/or rating specific types of effects, both positive and adverse, and the location of each effect. In this manner, a programming device, i.e. a programmer, uses the feedback to generate subsequent test stimulation programs. Initially, programs with unipolar electrode configurations are tested, but the programmer may generate bipolar electrode configurations to test if the patient rates the unipolar electrode combinations poorly. After the stimulation programs are tested and rated, the programmer sorts the tested programs based upon the feedback and presents the tested programs to the user. The user selects the best tested program to use for chronic stimulation therapy. Additionally, the patient may utilize the guided programming technique for continued therapy optimization.

Abstract translation: 描述了基于特定患者反馈产生测试刺激程序以指导刺激治疗的编程过程的技术。 患者通过列出和/或评估特定类型的效应（包括阳性和不良反应）以及每种效应的位置来描述测试刺激的积极影响和不利影响。 以这种方式，编程设备，即编程器，使用反馈来产生后续的测试刺激程序。 首先，测试具有单极电极配置的程序，但是程序员可以产生双极电极配置来测试患者是否对单极电极组合进行评估。 在对刺激程序进行测试和评估后，程序员将根据反馈对测试程序进行排序，并将测试的程序呈现给用户。 用户选择用于慢性刺激治疗的最佳测试程序。 此外，患者可以利用引导编程技术进行持续的治疗优化。

公开(公告)号：US08036737B2

公开(公告)日：2011-10-11

申请号：US11253391

申请日：2005-10-19

Applicant: Steven M. Goetz ,  Jordan A. Barnhorst ,  James M. Hartmann

Inventor： Steven M. Goetz ,  Jordan A. Barnhorst ,  James M. Hartmann

IPC: A61B5/05 ,  A61N1/00

CPC classification number: A61N1/08 ,  A61N2001/083

Abstract: Aspects of the present invention relate to automatic impedance measurements between one or more electrodes in a set of electrodes that may be associated with a lead of an implanted device. A voltage measurement that is associated with a stimulation pulse between the two electrodes may be made. The voltage measurement may be used to determine the impedance between the two electrodes. The impedance measurement may be made for each possible pair of electrodes in the set of electrodes. The impedance measurements may be displayed to a clinician on a user interface.

Abstract translation: 本发明的方面涉及可以与植入装置的引线相关联的一组电极中的一个或多个电极之间的自动阻抗测量。 可以进行与两个电极之间的刺激脉冲相关联的电压测量。 电压测量可用于确定两个电极之间的阻抗。 可以对该组电极中的每对可能的电极进行阻抗测量。 阻抗测量可以在用户界面上向临床医生显示。

公开(公告)号：US07885712B2

公开(公告)日：2011-02-08

申请号：US11940604

申请日：2007-11-15

Applicant: Steven M. Goetz ,  Donald R. Johnson ,  Touby A. Drew ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Theodore J. Stone ,  Earle T. Roberts

Inventor： Steven M. Goetz ,  Donald R. Johnson ,  Touby A. Drew ,  Andrew H. Houchins ,  Jeffrey T. Keacher ,  Theodore J. Stone ,  Earle T. Roberts

IPC: A61N1/08

CPC classification number: G06F19/3481 ,  G06F19/00 ,  G06F19/3418

Abstract: Techniques for increasing the safety of medical device programming using general purpose hardware, such as a general purpose personal computer, are described. In some embodiments, a system includes an intermediate computing device comprising an applications module. Information from the applications module, such as instructions for an implantable medical device (IMD), may be presented to a user via a user input terminal that is separate from the intermediate computing device. A user may interact with the user input terminal to select an instruction from the applications module, and the intermediate computing device may transmit the selected instruction to the IMD. In some embodiments, the intermediate computing device comprises a web server and the user input terminal comprises a web browser configured to access the web server. In other embodiments, the intermediate computing device comprises a client server and the user input terminal comprises a client.

Abstract translation: 描述用于增加使用通用硬件（例如通用个人计算机）的医疗设备编程安全性的技术。 在一些实施例中，系统包括包括应用模块的中间计算设备。 可以经由与中间计算设备分离的用户输入终端向用户呈现来自应用模块的信息，诸如可植入医疗设备（IMD）的指令。 用户可以与用户输入终端交互以从应用模块选择指令，并且中间计算设备可以将所选择的指令发送到IMD。 在一些实施例中，中间计算设备包括web服务器，并且用户输入终端包括被配置为访问web服务器的web浏览器。 在其他实施例中，中间计算设备包括客户端服务器，并且用户输入终端包括客户端。

公开(公告)号：US07878207B2

公开(公告)日：2011-02-01

申请号：US11186388

申请日：2005-07-20

Applicant: Steven M. Goetz ,  Todd V. Smith

Inventor： Steven M. Goetz ,  Todd V. Smith

IPC: A61B19/00 ,  A61B5/00

CPC classification number: A61B5/06 ,  A61B34/20 ,  A61B90/36 ,  A61B2034/2051 ,  A61N1/37252 ,  A61N1/3787 ,  G01V3/12

Abstract: In general, the invention is directed to techniques for locating an implanted object using an external antenna. The implanted object may be, for example, an internal antenna that facilitates recharging of and/or communication with an implantable medical device. An external device coupled to the external antenna drives the antenna with a plurality of waveforms. Asymmetry in the loading profile of the external antenna when it is driven by the plurality of waveforms allows the external device or another device to determine the location of the implanted object relative to the external antenna. The external device or other device may provide information to a user based on the determined location of the implanted object relative to the external antenna, such as information to help a user position the external antenna with respect to an internal antenna in embodiments in which the implanted object is an internal antenna.

公开(公告)号：US07848802B2

公开(公告)日：2010-12-07

申请号：US11591280

申请日：2006-10-31

Applicant: Steven M. Goetz ,  Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand

Inventor： Steven M. Goetz ,  Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand

IPC: A61N1/08

CPC classification number: A61N1/37247 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/36185

Abstract: The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. The disclosure also contemplates guided programming to select electrode combinations and parameter values to support efficacy. The techniques may be applied to a programming interface associated with a clinician programmer, a patient programmer, or both. A user interface permits a user to view electrodes from different perspectives relative to the lead. For example, the user interface provides a side view of a lead and a concentric axial view of the lead. The user interface may include an axial control medium to select and/or view electrodes at different axial positions along the length of a lead, and a rotational control medium to select and/or view electrodes at different angular positions around a circumference of the lead.

Abstract translation: 本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。 本公开还考虑了引导编程以选择电极组合和参数值以支持功效。 这些技术可以应用于与临床医生程序员，患者程序员或两者相关联的编程接口。 用户界面允许用户从相对于铅的不同角度来观察电极。 例如，用户界面提供引线的侧视图和引线的同心轴向视图。 用户界面可以包括轴向控制介质，用于选择和/或查看沿引线长度的不同轴向位置处的电极;以及旋转控制介质，用于选择和/或查看围绕引线圆周的不同角位置处的电极。

公开(公告)号：US07826902B2

公开(公告)日：2010-11-02

申请号：US11591178

申请日：2006-10-31

Applicant: Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand ,  Steven M. Goetz ,  Lynn M. Otten

Inventor： Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand ,  Steven M. Goetz ,  Lynn M. Otten

IPC: A61N1/00

CPC classification number: A61N1/0529 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0553 ,  A61N1/3605 ,  A61N1/36082 ,  A61N1/37247

Abstract: The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates a stimulation field on the display to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to anatomical regions of the patient.

Abstract translation: 本公开描述了允许用户通过定义刺激场来配置电刺激治疗的方法和系统。 在刺激引线植入患者体内之后，临床医生操纵显示器上的刺激场以包围病人的所需解剖区域。 以这种方式，临床医生确定要刺激的解剖区域，并且系统产生必要的刺激参数。 在一些情况下，显示代表植入引线的引线图标，以显示临床医师，其中引线相对于患者的解剖区域。

公开(公告)号：US07822483B2

公开(公告)日：2010-10-26

申请号：US11591299

申请日：2006-10-31

Applicant: Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand ,  Steven M. Goetz ,  Lynn M. Otten

Inventor： Richard T. Stone ,  Warren W. Ball ,  Carl D. Wahlstrand ,  Steven M. Goetz ,  Lynn M. Otten

IPC: A61N1/00

CPC classification number: A61N1/37247 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/36082

Abstract: The disclosure describes a method and system that generates an electrical field model of defined stimulation therapy and displays the electrical field model to a user via a user interface. The electrical field model is generated based upon a patient anatomy and stimulation parameters to illustrate which areas of a patient anatomical region will be covered by the electrical field during therapy. In addition, a neuron model may be applied to the electrical field model to generate an activation field model. The activation field model indicates which neurons will be activated by the electrical field in the anatomical region. These field models may be used by a clinician to determine effective therapy prior to stimulation delivery. In particular, the field models may be beneficial when programming non axi-symmetric, or three-dimensional (3D), leads which allow greater flexibility in creating stimulation fields.

Abstract translation: 本公开描述了一种产生定义的刺激疗法的电场模型并通过用户界面向用户显示电场模型的方法和系统。 基于患者解剖学和刺激参数产生电场模型，以说明在治疗期间患者解剖区域的哪些区域将被电场覆盖。 此外，神经元模型可以应用于电场模型以产生激活场模型。 激活场模型指示哪个神经元将被解剖区域中的电场激活。 临床医生可以使用这些现场模型来确定在刺激递送之前的有效治疗。 特别地，当编程非轴对称或三维（3D））引线时，场模型可能是有益的，这些引导允许在创建刺激场方面具有更大的灵活性。

公开(公告)号：US07819909B2

公开(公告)日：2010-10-26

申请号：US11388227

申请日：2006-03-23

Applicant: Steven M. Goetz ,  Michael T. Lee

Inventor： Steven M. Goetz ,  Michael T. Lee

IPC: A61N1/36

CPC classification number: A61N1/36135 ,  A61N1/37247 ,  A61N1/37264 ,  G06F19/00

Abstract: A programming device used to program delivery of therapy to a patient by a medical device, such as an implantable neurostimulator or pump, maintains or accesses a programming history for the patient. The programming history may take the form of a record of programs, e.g., combinations of therapy parameters, tested during one or more prior programming sessions. The programming device may analyze, or otherwise use the programming history to provide guidance information to a user, such as a clinician, which may assist the user in more quickly identifying one or more desirable programs during a current programming session.

Abstract translation: 用于通过诸如可植入神经刺激器或泵的医疗装置向患者传递治疗的程序设备维护或访问患者的编程历史。 编程历史可以采取程序记录的形式，例如在一个或多个在先的编程会话期间测试的治疗参数的组合。 编程设备可以分析或以其他方式使用编程历史来向诸如临床医师的用户提供指导信息，其可以在当前的编程会话期间帮助用户更快速地识别一个或多个期望的程序。