-
公开(公告)号：US20190389861A1
公开(公告)日：2019-12-26
申请号：US16254124
申请日：2019-01-22
Applicant: AbbVie Inc.
Inventor： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC: C07D471/22 , C07D471/16
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US20160039821A1
公开(公告)日：2016-02-11
申请号：US14774866
申请日：2014-03-12
Applicant: ABBVIE INC.
Inventor： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC: C07D471/22 , C07D471/16
CPC classification number: C07D471/22 , C07D471/16
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3 and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R1，R2，R6，Y1，Y2，Y3，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其是有用的 作为治疗疾病和病症的药剂，包括炎性疾病，癌症和AIDS。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US08980879B2
公开(公告)日：2015-03-17
申请号：US14203651
申请日：2014-03-11
Applicant: AbbVie Inc.
Inventor： Dachun Liu , John Pratt , Le Wang , Lisa A. Hasvold , Andrew Bogdan
IPC: C07D471/04 , C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5025 , A61K31/519 , A61K31/18 , C07D471/16 , C07D471/12 , C07D471/22
CPC classification number: A61K31/55 , C07D471/12 , C07D471/16 , C07D471/22 , Y02A50/463
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R1，R2，R6，Y1，Y2，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其可用作 治疗疾病和病症的药剂，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US20140275026A1
公开(公告)日：2014-09-18
申请号：US14206028
申请日：2014-03-12
Applicant: AbbVie Inc.
Inventor： Le Wang , John Pratt , Lisa A. Hasvold , Dachun Liu , Yujia Dai , Steven D. Fidanze , James H. Holms , Robert A. Mantei , Keith F. McDaniel , George S. Sheppard , William J. McClellan
IPC: C07D471/04
CPC classification number: C07D471/04 , C07D519/00
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, and R5 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R 1，R 2，R 3，R 4和R 5具有说明书中定义的任何值及其药学上可接受的盐，其可用作治疗疾病和病症的试剂 ，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US20230101559A1
公开(公告)日：2023-03-30
申请号：US17654547
申请日：2022-03-11
Applicant: AbbVie Inc.
Inventor： Andrew Bogdan , Steven Fidanze , Keith McDaniel , John Pratt , Le Wang
IPC: C07D401/12 , C07D213/64 , C07D401/04
Abstract: The present invention provides for compounds of formula (I) wherein R1, Y, X1, X2, R2, R3, R4, R5, R6, and m have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).
-
Patent Agency Ranking
![Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors](/abs-image/US/2018/07/31/US10035800B2/abs.jpg.150x150.jpg)
公开(公告)号：US10035800B2
公开(公告)日：2018-07-31
申请号：US14774866
申请日：2014-03-12
Applicant: AbbVie Inc.
Inventor： Steven D. Fidanze , Dauchun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC: A61K31/437 , C07D471/22 , C07D471/16
CPC classification number: C07D471/22 , A61P13/12 , A61P15/16 , A61P31/18 , A61P35/00 , C07D471/16
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y3, A1, A2, A3 and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US09493411B2
公开(公告)日：2016-11-15
申请号：US14206061
申请日：2014-03-12
Applicant: AbbVie Inc.
Inventor： Lisa A. Hasvold , John Pratt , Keith F. McDaniel , George S. Sheppard , Dachun Liu , Steven W. Elmore , Robert D. Hubbard
IPC: C07D207/335 , C07D207/36 , C07D207/34 , C07D401/04 , C07D403/04 , C07D405/04 , C07D407/04 , C07D409/04 , C07D413/04 , C07D471/04 , A61K31/496 , A61K31/506 , A61K31/381 , A61K31/341 , A61K31/422 , A61K31/4709 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D401/10 , C07D403/10 , C07D407/12 , C07D409/10 , C07D413/10
CPC classification number: C07D207/34 , C07D207/335 , C07D207/36 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/10 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/10 , C07D409/12 , C07D413/10 , C07D413/12 , C07D471/04
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, and R10 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US09321764B2
公开(公告)日：2016-04-26
申请号：US14206028
申请日：2014-03-12
Applicant: AbbVie Inc.
Inventor： Le Wang , John Pratt , Lisa A. Hasvold , Dachun Liu , Yujia Dai , Steven D. Fidanze , James H. Holms , Robert A. Mantei , Keith F. McDaniel , George S. Sheppard , William J. McClellan
IPC: C07D401/04 , A61K31/4353 , C07D471/04
CPC classification number: C07D471/04 , C07D519/00
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, and R5 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R 1，R 2，R 3，R 4和R 5具有说明书中定义的任何值及其药学上可接受的盐，其可用作治疗疾病和病症的试剂 ，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US20140256710A1
公开(公告)日：2014-09-11
申请号：US14203651
申请日：2014-03-11
Applicant: AbbVie Inc.
Inventor： Dachun Liu , John Pratt , Le Wang , Lisa A. Hasvold , Andrew Bogdan
IPC: C07D471/16
CPC classification number: A61K31/55 , C07D471/12 , C07D471/16 , C07D471/22 , Y02A50/463
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R1，R2，R6，Y1，Y2，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其可用作 治疗疾病和病症的药剂，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US20140256705A1
公开(公告)日：2014-09-11
申请号：US14203641
申请日：2014-03-11
Applicant: Abbvie Inc.
Inventor： Lisa A. Hasvold , Dachun Liu , Keith F. McDaniel , John Pratt , George S. Sheppard , Carol K. Wada , Kevin R. Woller
IPC: A61K31/5377 , A61K31/437 , A61K31/519 , A61K31/497 , C07D487/04 , A61K31/501 , C07D471/04 , A61K31/496
CPC classification number: A61K31/5377 , A61K31/437 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/519 , C07D471/04 , C07D487/04 , Y02A50/463
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, A1, A2, A3, A4, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R1，R2，A1，A2，A3，A4，X和Y具有说明书中定义的任何值及其药学上可接受的盐，其可用作 治疗疾病和病症，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
-
-
-
-
-
-
-
-
Search Results
25
records
(took 0.039 seconds)
