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公开(公告)号：US20150266873A1
公开(公告)日：2015-09-24
申请号：US14436364
申请日：2013-10-18
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Lee William Page , Alessia Millemaggi , Steven Howard , Gordon Saxty , Thomas Daniel Heightman
IPC: C07D471/04 , C07D487/04
CPC classification number: C07D471/04 , C07D403/14 , C07D487/04 , C07D519/00
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Abstract translation: 本发明涉及新的双环杂环化合物，包含所述化合物的药物组合物和所述化合物在治疗疾病中的用途。 癌症。
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公开(公告)号：US11643410B2
公开(公告)日：2023-05-09
申请号：US17643083
申请日：2021-12-07
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Steven Howard , James Edward Harvey Day , Ildiko Maria Buck , Charlotte Mary Griffiths-Jones , Gordon Saxty , Emiliano Tamanini , Nicola Elizabeth Wilsher
IPC: C07D471/04 , A61K31/5377
CPC classification number: C07D471/04 , A61K31/5377
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
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Patent Agency Ranking
公开(公告)号：US11225476B2
公开(公告)日：2022-01-18
申请号：US16795117
申请日：2020-02-19
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Steven Howard , James Edward Harvey Day , Ildiko Maria Buck , Charlotte Mary Griffiths-Jones , Gordon Saxty , Emiliano Tamanini , Nicola Elizabeth Wilsher
IPC: C07D471/04 , A61K31/5377
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：US10526311B2
公开(公告)日：2020-01-07
申请号：US15763724
申请日：2016-09-29
Inventor： Gianni Chessari , Steven Howard , Ildiko Maria Buck , Benjamin David Cons , Christopher Norbert Johnson , Rhian Sara Holvey , David Charles Rees , Jeffrey David St. Denis , Emiliano Tamanini , Bernard Thomas Golding , Ian Robert Hardcastle , Celine Florence Cano , Duncan Charles Miller , Martin Edward Mäntylä Noble , Roger John Griffin , James Daniel Osborne , Joanne Peach , Arwel Lewis , Kim Louise Hirst , Benjamin Paul Whittaker , David Wyn Watson , Dale Robert Mitchell
IPC: C07D401/06 , A61K31/4439 , C07D401/14 , C07D403/06 , C07D407/14 , C07D409/14 , C07D417/14 , A61P35/00 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06
Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
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公开(公告)号：US09980973B2
公开(公告)日：2018-05-29
申请号：US15411463
申请日：2017-01-20
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Lee William Page , Thomas Daniel Heightman , Alessia Millemaggi , Steven Howard , Gordon Saxty
IPC: A61K31/553 , A61K31/5377 , A61K31/496 , A61K31/541 , A61K31/5375 , A61K31/551 , A61K31/506 , A61K31/4985 , A61K31/5025
CPC classification number: A61K31/553 , A61K31/496 , A61K31/4985 , A61K31/5025 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/541 , A61K31/551
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：US09617283B2
公开(公告)日：2017-04-11
申请号：US14436345
申请日：2013-10-18
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Lee William Page , Ildiko Maria Buck , James Edward Harvey Day , Steven Howard , Gordon Saxty , Christopher William Murray , Anna Hopkins
IPC: C07D403/14 , C07D471/04 , C07D487/04 , C07D519/00
CPC classification number: C07D519/00 , C07D403/14 , C07D471/04 , C07D487/04
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
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公开(公告)号：US20150259359A1
公开(公告)日：2015-09-17
申请号：US14436345
申请日：2013-10-18
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Gianni Chessari , Christopher Norbert Johnson , Lee William Page , Ildiko Maria Buck , James Edward Harvey Day , Steven Howard , Gordon Saxty , Christopher William Murray , Anna Hopkins
IPC: C07D519/00 , C07D487/04 , C07D471/04
CPC classification number: C07D519/00 , C07D403/14 , C07D471/04 , C07D487/04
Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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