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32 条记录 (耗时 0.022 秒)

    Novel compounds as histone deacetylase inhibitors
    12.
    发明申请
    Novel compounds as histone deacetylase inhibitors 审中-公开
    新型化合物作为组蛋白脱乙酰酶抑制剂

    公开(公告)号：US20050176686A1

    公开(公告)日：2005-08-11

    申请号：US10624571

    申请日：2003-07-23

    申请人： Alexander Maurer ,  Sascha Hoevelmann ,  Elke Martin ,  Bernd Hentsch ,  Michael Gassen ,  Juergen Kraus ,  Rolf Krauss ,  Adam-Spencer Vincek

    发明人： Alexander Maurer ,  Sascha Hoevelmann ,  Elke Martin ,  Bernd Hentsch ,  Michael Gassen ,  Juergen Kraus ,  Rolf Krauss ,  Adam-Spencer Vincek

    IPC分类号： A61K31/19 ,  A61K31/66 ,  C07C259/04

    CPC分类号： C07C259/04 ,  C07C2601/08 ,  C07C2601/14

    摘要： The present invention is directed to compounds of the general formula (I) or pharmaceutical acceptable salts or physiologically functional derivatives thereof wherein: n is a non-aromatic ring system containing two to seven carbon atoms, wherein the ring system can contain one ore two double bonds; X is C, CH or CH2; Y is selected from C, CH, CH2, S, NR, CH2-CH2, H2C—CH, HC—CH2, C—CH2, H2C—C, or C—C; one or more of the hydrogen atoms can optionally be substituted by one or more substituents R′; each of the dotted lines means a single, a double or triple bond with the exclusion of a combination of a triple with triple bond and a double with a triple bond; R′ is independently H, —CN, alkyl, cycloalkyl, aminoalkyl, alkylamino, alkoxy, —OH, —SH, alkylthio, hydroxyalkyl, hydroxyalkylamino, halogene, haloalkyl, haloalkyloxy; R is H, an alkyl or cycloalkyl group; Z is CH, C, or P; p is 0 or 1.

    摘要翻译： 本发明涉及通式（I）的化合物或其药学上可接受的盐或生理功能衍生物，其中：n是含有2至7个碳原子的非芳族环系统，其中所述环体系可以包含一个二价双 债券 X是C，CH或CH 2; Y选自C，CH，CH 2，S，NR，CH 2 -CH 2，H 2， C-CH，HC-CH 2，C-CH 2，H 2 CC或CC; 一个或多个氢原子可以任选被一个或多个取代基R'取代; 每个虚线意味着单，双或三键，排除三元组与三键的组合和具有三键的双键; R'独立地是H，-CN，烷基，环烷基，氨基烷基，烷基氨基，烷氧基，-OH，-SH，烷硫基，羟基烷基，羟烷基氨基，卤素基，卤代烷基，卤代烷氧基。 R是H，烷基或环烷基; Z是CH，C或P; p为0或1。

    Apparatus and method for the transport of articles forming a mass flow as well as apparatus for filling a subsequent apparatus with rod-shaped articles
    14.
    发明授权
    Apparatus and method for the transport of articles forming a mass flow as well as apparatus for filling a subsequent apparatus with rod-shaped articles 失效
    用于输送形成质量流的制品的装置和方法以及用于填充具有棒状制品的后续装置的装置

    公开(公告)号：US07350637B2

    公开(公告)日：2008-04-01

    申请号：US11486251

    申请日：2006-07-14

    申请人： Jürgen Krössmann ,  Alexander Maurer

    发明人： Jürgen Krössmann ,  Alexander Maurer

    IPC分类号： B65G1/00

    CPC分类号： B65G47/71 ,  A24C5/35 ,  B65G47/5154 ,  B65G47/647

    摘要： Apparatus for transporting articles forming a mass flow from an input device to an output device, including an endless conveying element with a transport run and a return run, the conveying element being guided about at least three rollers designed as a driving and/or deflecting element, wherein the transport run can be moved out of a throughflow position in which the transport run exhibits its maximum length, into a discharge position in which the transport run is shortened from the maximum length, and vice versa, further wherein at least one of the deflecting and/or driving rollers is movable relative to the other deflecting and/or driving rollers for altering the length of the transport run.

    摘要翻译： 用于将形成从输入装置到输出装置的质量流的物品输送到输送装置的装置，包括具有输送段和回流段的循环输送元件，所述输送元件围绕设计为驱动和/或偏转元件的至少三个辊被引导 ，其中所述运输运行可以从所述运输运行展现出其最大长度的通流位置移动到所述运输运行从所述最大长度缩短的排放位置，反之亦然，其中至少一个 偏转和/或驱动辊相对于另一个偏转和/或驱动辊可移动，用于改变运输运行的长度。

    Electric motor for a drive of a vehicle, in particular railroad drives, and a drive having such an electric motor
    15.
    发明申请
    Electric motor for a drive of a vehicle, in particular railroad drives, and a drive having such an electric motor 审中-公开
    用于车辆驱动的电动机，特别是铁路驱动器，以及具有这种电动机的驱动器

    公开(公告)号：US20070182258A1

    公开(公告)日：2007-08-09

    申请号：US10563525

    申请日：2004-06-24

    申请人： Bernhard Klaussner ,  Gerhard Maul ,  Alexander Maurer

    发明人： Bernhard Klaussner ,  Gerhard Maul ,  Alexander Maurer

    IPC分类号： H02K1/04 ,  H02K9/00 ,  H02K3/00

    CPC分类号： H02K3/50 ,  H02K1/20 ,  H02K3/30 ,  H02K3/345 ,  H02K3/48 ,  H02K3/487

    摘要： The invention relates to a drive unit for a vehicle and an electric motor that is suitable therefore, comprising a rotor and a stator (1) which is formed by a sheet metal pack (2) and is provided with grooves, at least one winding (3a) being disposed in said grooves (3). The electric motor is penetrated by cooling air. In order to keep production costs low and obtain thermal class 200, the winding (3a) is formed from round wires (7) that are provided with an insulation (12) while the coil heads (4) are embedded in a temperature-resistant elastic material (4a) so as to be protected against external influences.

    摘要翻译： 本发明涉及一种适用于车辆的驱动单元和电动马达，其适用于包括转子和定子（1），该定子由金属板（2）形成并且设置有凹槽，至少一个绕组 3a）设置在所述槽（3）中。 电动机被冷却空气穿透。 为了保持生产成本低并获得200级的热等级，绕组（3a）由设有绝缘层（12）的圆形线（7）形成，而线圈头（4）嵌入耐温 弹性材料（4a），以防止外部影响。

    Process for making mixed granulates from condensed phosphates and builder salts
    17.
    发明授权
    Process for making mixed granulates from condensed phosphates and builder salts 失效
    从缩合磷酸盐和助洗剂盐制备混合颗粒的方法

    公开(公告)号：US4517109A

    公开(公告)日：1985-05-14

    申请号：US542075

    申请日：1983-10-14

    申请人： Karl Merkenich ,  Horst-Dieter Wasel-Nielen ,  Alexander Maurer ,  Renate Adrian

    发明人： Karl Merkenich ,  Horst-Dieter Wasel-Nielen ,  Alexander Maurer ,  Renate Adrian

    IPC分类号： C11D3/06 ,  C11D7/16

    CPC分类号： C11D3/06 ,  C11D3/062

    摘要： The disclosure provides a process for making mixed granulates from water-soluble condensed phosphates and at least one builder salt by subjecting the components making the granulate to granulation in the presence of water. To this end, the disclosure provides:(a) for water to be sprayed on to a mixture of the condensed phosphate, the builder salt and an ammonium polyphosphate as a binder, and for the mixture to be granulated, or(b) for an aqueous solution or suspension of ammonium polyphosphate to be sprayed on to the mixture of condensed phosphate and builder salt, and for the mixture to be granulated.

    摘要翻译： 本公开提供了一种由水溶性缩合磷酸盐和至少一种助洗剂盐制备混合颗粒的方法，该方法是使制粒颗粒的组分在水存在下进行造粒。 为此，本公开内容提供：（a）将水喷雾到缩合磷酸盐，助洗剂盐和作为粘合剂的多磷酸铵的混合物上，并且对于待造粒的混合物，或（b） 水溶液或多磷酸铵的悬浮液喷雾到缩合磷酸盐和助洗剂盐的混合物中，并将混合物制粒。

    Linear, substantially water-insoluble ammonium polyphosphates and process for making them
    18.
    发明授权
    Linear, substantially water-insoluble ammonium polyphosphates and process for making them 失效
    线性，基本上不溶于水的多磷酸铵及其制备方法

    公开(公告)号：US4511546A

    公开(公告)日：1985-04-16

    申请号：US464982

    申请日：1983-02-08

    申请人： Klaus Schrodter ,  Alexander Maurer

    发明人： Klaus Schrodter ,  Alexander Maurer

    IPC分类号： C01B25/40 ,  C01B25/30

    CPC分类号： C01B25/405

    摘要： The disclosure relates to a process for making linear, substantially water-insoluble ammonium polyphosphates of the general formula (NH.sub.4 PO.sub.3).sub.10-1000 by heating and continuously mixing phosphorus pentoxide and ammonium orthophosphate in the presence of ammonia and tempering the resulting reaction product over a period of several hours at 200.degree. to 400.degree. C. in the presence of ammonia. To this end, the phosphorus pentoxide and ammonium orthophosphate are subjected at 50.degree. to 150.degree. C. to the following successive operations which provide(a) for them to be reacted with ammonia over a period of 5 to 15 minutes under an overpressure of 1-2 millibars,(b) for them to be mixed under nitrogen for 10 to 60 minutes at atmospheric pressure while arresting the supply of ammonia,(c) for them to be reacted with ammonia over a period of 1 to 3 hours under a pressure 1 to 5 millibars lower than atmospheric pressure, andthe reaction product is tempered, the ammonia being used in an overall stoichiometric excess of at most 20 mol %.The disclosure is also concerned with the ammonium polyphosphates so obtainable which are characterized by the following typical data which provide:(a) for the solubility of a 10 weight % suspension in pure water at 25.degree. C. to be less than 0.8 g per 100 g suspension;(b) for the viscosity of a 10 weight % suspension in pure water at 25.degree. C. to be at most 100 mPa.s;(c) for the viscosity of a 30 weight % suspension in a polyesterpolyol at 25.degree. C. to be at most 50 Pa.s.

    摘要翻译： 本公开内容涉及通过在氨的存在下加热并连续混合五氧化二磷和正磷酸铵来制备具有通式（NH 4 PO 3）10-1000的直链，基本上不溶于水的多磷酸铵的方法，并在所述反应产物中回火一段时间 在氨存在下，在200-400℃下进行数小时。 为此，五氧化二磷和正磷酸铵在50至150℃下经历以下连续操作，其提供（a）使它们在5至15分钟的时间内与氨反应，过压1 -2毫巴，（b）使它们在大气压下在氮气下混合10至60分钟，同时阻止氨的供应，（c）使它们在1至3小时的时间内在压力下与氨反应 1至5毫巴低于大气压，并且反应产物被回火，氨的总化学计量过量最多为20摩尔％。 本公开还涉及可获得的多磷酸铵，其特征在于以下典型数据，其提供：（a）10重量％悬浮液在25℃的纯水中的溶解度小于0.8g / 100 g悬浮液 （b）在25℃的纯水中10重量％悬浮液的粘度为至多100mPa.s; （c）25℃下聚酯多元醇中30重量％悬浮液的粘度为至多50Pa.s。

    Corrosion-inhibiting pigment and paint composition
    19.
    发明授权
    Corrosion-inhibiting pigment and paint composition 失效
    防腐蚀颜料和涂料组成

    公开(公告)号：US4337092A

    公开(公告)日：1982-06-29

    申请号：US193550

    申请日：1980-10-03

    申请人： Klaus Hestermann ,  Alexander Maurer ,  Joachim Kandler ,  Gerhard Mietens ,  Herbert Beumling

    发明人： Klaus Hestermann ,  Alexander Maurer ,  Joachim Kandler ,  Gerhard Mietens ,  Herbert Beumling

    IPC分类号： C09C1/00 ,  C09C1/04 ,  C09D5/08

    CPC分类号： C09D5/084

    摘要： The invention relates to a corrosion-inhibiting active pigment for use in the surface protection of iron and iron alloys. The pigment consists of a mixture of calcium hydrogen phosphate dihydrate, magnesium hydrogen phosphate trihydrate and zinc oxide. More specifically, the mixture contains 2 to 98 weight % of ZnO and 98 to 2 weight % of phosphate components. These in turn contain 3 to 97 weight % of CaHPO.sub.4 .multidot.2 H.sub.2 O and 97 to 3 weight % of MgHPO.sub.4 .multidot.3 H.sub.2 O. The active pigment is suitable for use in painting compositions or lacquers.

    摘要翻译： 本发明涉及用于铁和铁合金表面保护的腐蚀抑制活性颜料。 颜料由磷酸氢二钙二水合物，磷酸氢钙三水合物和氧化锌的混合物组成。 更具体地，该混合物含有2至98重量％的ZnO和98至2重量％的磷酸盐组分。 这些又包含3至97重量％的CaHPO 4/2 H 2 O和97至3重量％的MgHPO 4 x 3 H 2 O. 活性颜料适用于涂漆组合物或漆。

    STENT DEVICE DELIVERY SYSTEM WITH A VARYING RADIAL PROFILE PULL MEMBER
    20.
    发明申请
    STENT DEVICE DELIVERY SYSTEM WITH A VARYING RADIAL PROFILE PULL MEMBER 有权
    具有变化的径向轮廓牵引构件的STENT设备传送系统

    公开(公告)号：US20110137400A1

    公开(公告)日：2011-06-09

    申请号：US12958123

    申请日：2010-12-01

    申请人： Jürgen Dorn ,  Markus Forster ,  Daniel Dietrich ,  Alexander Maurer ,  Erhard Elsasser

    发明人： Jürgen Dorn ,  Markus Forster ,  Daniel Dietrich ,  Alexander Maurer ,  Erhard Elsasser

    IPC分类号： A61F2/82 ,  B65B11/50

    CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2210/0076 ,  A61F2240/001

    摘要： A stent device delivery system and method of making. The stent device delivery system includes a stent device, an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device, and a pull member. The outer sheath may include a first layer and a reinforcement layer that are laminated together, a portion of the pull member captured radially between the first layer and the reinforcement layer. At least a partial length of the captured portion of the pull member may be formed with a varying radial profile.

    摘要翻译： 支架装置输送系统及其制造方法。 支架装置递送系统包括支架装置，以支架装置的径向紧凑的输送构造覆盖支架装置的外护套和拉构件。 外护套可以包括层压在一起的第一层和加强层，拉动构件的一部分径向地捕获在第一层和加强层之间。 牵引构件的捕获部分的至少一部分长度可以形成为具有变化的径向轮廓。