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公开(公告)号：US20120041549A1
公开(公告)日：2012-02-16
申请号：US13282746
申请日：2011-10-27
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/013 , A61F2/2415 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0036 , A61F2250/0039
摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。
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公开(公告)号：US20120016471A1
公开(公告)日：2012-01-19
申请号：US13240771
申请日：2011-09-22
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：直径为21法郎或更小的输送导管; 布置在输送导管内的可扩张锚; 以及设置在输送导管内的置换瓣膜。 本发明还包括用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将具有不超过21个法兰的直径的导管插入患者体内; 通过导管将血管内递送更换瓣膜和可扩张锚固件到心脏瓣膜附近; 并部署锚杆和更换阀。
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公开(公告)号：US08048153B2
公开(公告)日：2011-11-01
申请号：US12132304
申请日：2008-06-03
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：直径为21法郎或更小的输送导管; 布置在输送导管内的可扩张锚; 以及设置在输送导管内的置换瓣膜。 本发明还包括用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将具有不超过21个法兰的直径的导管插入患者体内; 通过导管将血管内递送更换瓣膜和可扩张锚固件到心脏瓣膜附近; 并部署锚杆和更换阀。
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公开(公告)号：US20090054969A1
公开(公告)日：2009-02-26
申请号：US12264082
申请日：2008-11-03
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider , Jeff Krolik
CPC分类号： A61F2/2409 , A61F2/013 , A61F2/2415 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2220/0075 , A61F2230/0054 , A61F2230/0078 , A61F2250/0036 , A61F2250/0039
摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。
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公开(公告)号：US08623078B2
公开(公告)日：2014-01-07
申请号：US13155902
申请日：2011-06-08
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US20110276129A1
公开(公告)日：2011-11-10
申请号：US13155902
申请日：2011-06-08
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US08182528B2
公开(公告)日：2012-05-22
申请号：US10746872
申请日：2003-12-23
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US07959672B2
公开(公告)日：2011-06-14
申请号：US10911059
申请日：2004-08-03
申请人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
发明人： Amr Salahieh , Brian D. Brandt , Dwight P. Morejohn , Ulrich R. Haug , Jean-Pierre Dueri , Hans F. Valencia , Robert A. Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US07959666B2
公开(公告)日：2011-06-14
申请号：US10982388
申请日：2004-11-05
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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公开(公告)号：US08858620B2
公开(公告)日：2014-10-14
申请号：US13157733
申请日：2011-06-10
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans F. Valencia , Daniel Hildebrand , Brian D. Brandt , Dwight P. Morejohn , Claudio Argento , Tom Saul , Ulrich R. Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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