公开(公告)号：US20210244937A1

公开(公告)日：2021-08-12

申请号：US17033455

申请日：2020-09-25

申请人： Michael CALOMENI ,  Brian D. BRANDT ,  Ari RYAN ,  Rezi SHIRAZI ,  Janine ROBINSON

发明人： Michael CALOMENI ,  Brian D. BRANDT ,  Ari RYAN ,  Rezi SHIRAZI ,  Janine ROBINSON

IPC分类号： A61M60/857 ,  A61M60/237 ,  A61M60/126 ,  A61M60/808 ,  A61M60/865 ,  A61M60/81

摘要： Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

公开(公告)号：US09861476B2

公开(公告)日：2018-01-09

申请号：US13290369

申请日：2011-11-07

申请人： Amr Salahieh ,  Brian D. Brandt ,  Robert A. Geshlider ,  Dwight P. Morejohn ,  Tom Saul

发明人： Amr Salahieh ,  Brian D. Brandt ,  Robert A. Geshlider ,  Dwight P. Morejohn ,  Tom Saul

IPC分类号： A61F2/24 ,  A61F2/95

CPC分类号： A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2002/9528 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/006

摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.

公开(公告)号：US08894703B2

公开(公告)日：2014-11-25

申请号：US13166184

申请日：2011-06-22

申请人： Amr Salahieh ,  Hans F. Valencia ,  Brian D. Brandt ,  Claudio Argento ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Daniel Hildebrand ,  Dwight P. Morejohn ,  Tom Saul

发明人： Amr Salahieh ,  Hans F. Valencia ,  Brian D. Brandt ,  Claudio Argento ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Daniel Hildebrand ,  Dwight P. Morejohn ,  Tom Saul

IPC分类号： A61F2/24 ,  A61B17/064 ,  A61F2/90 ,  A61B17/068 ,  A61B17/22 ,  A61B17/221

CPC分类号： A61F2/2427 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/221 ,  A61B2017/22035 ,  A61B2017/2215 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/90 ,  A61F2002/9534 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/005 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/001

摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.

摘要翻译： 本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。 在一些实施例中，递送系统包括多个第一可致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件 元件处于第二配置并且从输送系统释放植入物。

公开(公告)号：US08840663B2

公开(公告)日：2014-09-23

申请号：US10746280

申请日：2003-12-23

申请人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider ,  Jeff Krolik

发明人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider ,  Jeff Krolik

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0083 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0039

摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.

摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。

公开(公告)号：US08623076B2

公开(公告)日：2014-01-07

申请号：US13240771

申请日：2011-09-22

申请人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider ,  Jeff Krolik

发明人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider ,  Jeff Krolik

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2002/9528 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0065 ,  A61F2230/0078 ,  A61F2250/006

摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.

摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：直径为21法郎或更小的输送导管; 布置在输送导管内的可扩张锚; 以及设置在输送导管内的置换瓣膜。 本发明还包括用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将具有不超过21个法兰的直径的导管插入患者体内; 通过导管将血管内递送更换瓣膜和可扩张锚固件到心脏瓣膜附近; 并部署锚杆和更换阀。

公开(公告)号：US08211170B2

公开(公告)日：2012-07-03

申请号：US12578463

申请日：2009-10-13

申请人： David Paul ,  Benjamin Sutton ,  Brian McCollum ,  Brian D. Brandt ,  Emma Leung ,  Kenneth M. Martin ,  Amr Salahieh ,  Daniel Hildebrand

发明人： David Paul ,  Benjamin Sutton ,  Brian McCollum ,  Brian D. Brandt ,  Emma Leung ,  Kenneth M. Martin ,  Amr Salahieh ,  Daniel Hildebrand

IPC分类号： A61F2/24

摘要： Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.

公开(公告)号：US20110276129A1

公开(公告)日：2011-11-10

申请号：US13155902

申请日：2011-06-08

申请人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider

发明人： Amr Salahieh ,  Brian D. Brandt ,  Dwight P. Morejohn ,  Ulrich R. Haug ,  Jean-Pierre Dueri ,  Hans F. Valencia ,  Robert A. Geshlider

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0065 ,  A61F2230/0078 ,  A61F2250/0069

摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。

公开(公告)号：US07748389B2

公开(公告)日：2010-07-06

申请号：US10972287

申请日：2004-10-21

申请人： Amr Salahieh ,  Brian D. Brandt ,  Robert A. Gleshlider ,  Dwight P. Morejohn ,  Tom Saul

发明人： Amr Salahieh ,  Brian D. Brandt ,  Robert A. Gleshlider ,  Dwight P. Morejohn ,  Tom Saul

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2002/9528 ,  A61F2250/006

摘要： The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.

摘要翻译： 本发明涉及用于血管内置换患者心脏瓣膜的方法的装置。 该装置包括在锚固件的近端上具有小叶接合元件的可扩张锚和更换阀。 传单接合元件可用于防止远端迁移并确保设备的正确定位。

公开(公告)号：US20210252274A1

公开(公告)日：2021-08-19

申请号：US17033493

申请日：2020-09-25

申请人： Harshveer DHALIWAL ,  Michael CALOMENI ,  Brian D. BRANDT ,  Ari RYAN ,  Reza SHIRAZI ,  Janine ROBINSON

发明人： Harshveer DHALIWAL ,  Michael CALOMENI ,  Brian D. BRANDT ,  Ari RYAN ,  Reza SHIRAZI ,  Janine ROBINSON

IPC分类号： A61M60/414 ,  A61M60/531 ,  A61M60/808

摘要： Catheter blood pumps that include an expandable pump portion. The pump portions include an collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

公开(公告)号：US20210023285A1

公开(公告)日：2021-01-28

申请号：US16936160

申请日：2020-07-22

申请人： Brian D. BRANDT

发明人： Brian D. BRANDT

IPC分类号： A61M1/10

摘要： Catheter blood pumps that include an expandable pump portion, which include an expandable impeller housing. The housings include an expandable blood conduit that defines a blood lumen, and one or more pluralities of expandable struts extending axially from an end region of the expandable blood conduit. At least one of the pluralities of struts are non-unitary with a blood conduit at the end region.