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公开(公告)号：US20250093347A1
公开(公告)日：2025-03-20
申请号：US18578665
申请日：2023-01-17
Inventor： Ruijun DENG , Shicai WANG , Yang SONG , Ding DING
IPC: G01N33/543 , B01L3/00
Abstract: Provided is a biosensor. The biosensor includes: a base substrate; a plurality of detection units disposed on a side of the base substrate, wherein each of the plurality of detection units includes a gate; a first drive signal line disposed on the side of the base substrate and electrically connected to the gate; and a cover plate fixedly connected to the side of the base substrate, wherein a plurality of recesses are defined in a side, proximal to the base substrate, of the cover plate.
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公开(公告)号：US20250033056A1
公开(公告)日：2025-01-30
申请号：US18713233
申请日：2022-04-20
Inventor： Ding DING , Jian XU , Lin DENG , Zhukai LIU
IPC: B01L3/00
Abstract: A microwell array chip, a use method therefor, and a detection apparatus. The microwell array chip includes a microwell array substrate, and the microwell array substrate includes n reaction chambers, and an idle region; an array of the n reaction chambers is disposed in the microwell array substrate, and the idle region is disposed around the n reaction chambers; each reaction chamber is configured to accommodate a sample to be tested, and the shape of an orthographic projection of the reaction chamber on a first reference plane where the first main surface is located is of a regular N-gon; the area of the idle region is divided into n′ virtual units, and the shape of the orthographic projection of each virtual unit on the first reference plane is the same as the shape of the orthographic projection of the reaction chamber on the first reference plane.
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公开(公告)号：US20250002981A1
公开(公告)日：2025-01-02
申请号：US18263456
申请日：2022-04-29
Inventor： Zijian ZHAO , Ding DING , Shinying LAU
IPC: C12Q1/6841
Abstract: The present disclosure provides reagents such as a hybridization solution and a pre-digestion treatment solution and kits for fluorescence in situ hybridization, and also provides a detection method for fluorescence in situ hybridization using the above reagents or kits. The fluorescence in situ hybridization can be achieved with ultrafast speed and high resolution.
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公开(公告)号：US20240299934A1
公开(公告)日：2024-09-12
申请号：US18027097
申请日：2022-04-27
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L2300/04 , B01L2300/0645 , B01L2300/161 , B01L2300/1805
Abstract: The present disclosure provides a micro-fluidic chip and a reaction system. The micro-fluidic chip includes: a base substrate; a micro-cavity defining layer on the base substrate and defining a plurality of micro-reaction chambers; a cover plate on a side of the micro-cavity defining layer away from the base substrate; a heating layer disposed between the micro-cavity defining layer and one of the base substrate and the cover plate, and configured to heat the plurality of micro-reaction chambers. One of the base substrate and the cover plate, which is away from the heating layer, has a first surface and a second surface, the first surface faces the heating layer, the second surface faces away from the heating layer, and a area of the second surface is larger than that of the first surface.
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公开(公告)号：US20240293828A1
公开(公告)日：2024-09-05
申请号：US17996129
申请日：2021-10-22
Inventor： Kang PENG , Zhukai LIU , Ding DING
CPC classification number: B04B7/08 , B01L3/502707 , B01L2400/0409
Abstract: A centrifugal structure member of a microfluidic chip and a centrifuge are provided. The centrifugal structure member of a microfluidic chip includes: a connecting portion (10) configured to connect to a rotor of a centrifuge; a support portion (20) fixedly connected or integrally formed with the connecting portion (10), and having an inclined outer surface forming an included angle with the rotation axis (50) of the rotor of the centrifuge; and a mounting portion (30) connected with or formed on the inclined outer surface, and configured to detachably mount the microfluidic chip (40) on the support portion (20).
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Patent Agency Ranking
公开(公告)号：US20240246074A1
公开(公告)日：2024-07-25
申请号：US18016359
申请日：2022-02-18
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yunqing MU , Dandan CHEN , Ding DING
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L2300/0816 , B01L2300/0858 , B01L2300/087 , B01L2300/088 , B01L2400/086
Abstract: A microfluidic flow channel structure and a microfluidic chip are described. The microfluidic flow channel structure includes a main chamber, wherein the main chamber includes at least two division zones and a reaction zone, and the at least two division zones are respectively connected with the reaction zone, wherein each division zone includes a first division wall, and the first division wall is provided with an opening for liquid inlet; a diversion structure is arranged at the opening of at least one division zone, and the diversion structure at least includes a first diversion wall, which is arranged opposite the first division wall; a first division channel is formed between the first diversion wall and the first division wall, and the first division channel includes at least two liquid outlets.
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17.发明公开公开(公告)号：US20230158500A1
公开(公告)日：2023-05-25
申请号：US17753161
申请日：2021-03-12
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Ruijun DENG , Fan YANG , Zhukai LIU , Ding DING
IPC: B01L3/00 , B01L7/00 , C12Q1/6844 , G01N21/64
CPC classification number: B01L3/502761 , B01L7/52 , C12Q1/6844 , G01N21/64 , B01L2200/0647 , B01L2200/16 , B01L2300/0654 , B01L2300/18 , B01L2300/161
Abstract: The present disclosure provides an array substrate, a microfluidic device, a microfluidic system, and a fluorescence detection method. The array substrate includes at least one recess, the array substrate is located in a plane, and a ratio of an area of an orthographic projection of the at least one recess on the plane to an area of an orthographic projection of the array substrate on the plane is between 0.05 and 0.60.
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公开(公告)号：US20250006365A1
公开(公告)日：2025-01-02
申请号：US18275018
申请日：2022-07-29
Applicant: BOE Technology Group Co., Ltd.
Abstract: Disclosed are a disease analysis method, a training method and apparatus of a disease analysis model, the disease analysis method includes: acquiring first omics data and second omics data of a patient, wherein first omics includes a plurality of first loci and second omics includes a plurality of second loci; inputting the first omics data and the second omics data into a fusion algorithm model to obtain a predicted result of the patient, wherein the fusion algorithm model is formed by fusion and construction according to a first omics model and a second omics model, the first omics model is constructed according to sample data of the first omics, and the second omics model is constructed according to sample data of the second omics.
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公开(公告)号：US20240397945A1
公开(公告)日：2024-12-05
申请号：US18262657
申请日：2022-07-04
Inventor： Zijian ZHAO , Ding DING , Siyi YIN
Abstract: A preservation solution of magnetic beads includes a surfactant, a water-soluble salt and a bacteriostatic agent.
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公开(公告)号：US20240183848A1
公开(公告)日：2024-06-06
申请号：US17778177
申请日：2021-06-08
Inventor： Haonan LIU , Ding DING
IPC: G01N33/543 , B01L3/00
CPC classification number: G01N33/54386 , B01L3/502761 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , G01N2470/04
Abstract: The present application discloses a first substrate for a microfluidic chip, the microfluidic chip, and a method for processing a sample. The first substrate includes a first injection port, a first reacting region, a first upstream end of which is communicated with the first injection port, a second injection port, a second reacting region, an upstream end of which is communicated with the second injection port, and a downstream end of which is communicated with a second upstream end of the first reacting region, a fluid backflow prevention region between the second reacting region and the first reacting region, an upstream end of which is communicated with the downstream end of the second reacting region, and a downstream end of which is communicated with the second upstream end of the first reacting region, and an exit port communicated with a downstream end of the first reacting region.
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