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    Nucleotide sequences for encoding of the lysR2-gene
    11.
    发明申请
    Nucleotide sequences for encoding of the lysR2-gene 失效
    编码lysR2基因的核苷酸序列

    公开(公告)号：US20050282259A1

    公开(公告)日：2005-12-22

    申请号：US11178485

    申请日：2005-07-12

    申请人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    发明人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    IPC分类号： C07K14/34 ,  C12N1/21 ,  C12N15/31 ,  C12P13/08

    CPC分类号： C12P13/08 ,  C07K14/34

    摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

    摘要翻译： 分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸， 其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸， 和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒 形式，以及使用多核苷酸序列作为杂交探针。

    Nucleotide sequences for encoding of the lysR2-gene
    12.
    发明授权
    Nucleotide sequences for encoding of the lysR2-gene 失效
    编码lysR2基因的核苷酸序列

    公开(公告)号：US07416863B2

    公开(公告)日：2008-08-26

    申请号：US11178485

    申请日：2005-07-12

    申请人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    发明人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    IPC分类号： C12P19/34

    CPC分类号： C12P13/08 ,  C07K14/34

    摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c),and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

    摘要翻译： 分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸， 其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸， 和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒 形式，以及使用多核苷酸序列作为杂交探针。

    Nucleotide sequences for encoding of the lysR2-gene
    16.
    发明授权
    Nucleotide sequences for encoding of the lysR2-gene 失效
    编码lysR2基因的核苷酸序列

    公开(公告)号：US07078502B2

    公开(公告)日：2006-07-18

    申请号：US09826909

    申请日：2001-04-06

    申请人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    发明人： Bettina Moeckel ,  Mike Farwick ,  Thomas Hermann ,  Caroline Kreutzer ,  Walter Pfefferle

    IPC分类号： C07H21/02 ,  C07H21/04 ,  C12N15/00 ,  C12N15/09 ,  C12N15/63

    CPC分类号： C12P13/08 ,  C07K14/34

    摘要： Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the lysR2 gene is present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

    摘要翻译： 分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸，b）多核苷酸， 其编码多肽，其包含与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸， 和d）包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少lysR2基因存在于减毒 形式，以及使用多核苷酸序列作为杂交探针。

    Nucleotide sequences coding for the luxR gene
    19.
    发明授权
    Nucleotide sequences coding for the luxR gene 失效
    编码luxR基因的核苷酸序列

    公开(公告)号：US06875586B2

    公开(公告)日：2005-04-05

    申请号：US09903771

    申请日：2001-07-13

    申请人： Bettina Moeckel ,  Caroline Kreutzer ,  Brigitte Bathe

    发明人： Bettina Moeckel ,  Caroline Kreutzer ,  Brigitte Bathe

    IPC分类号： C07K14/34 ,  C12N1/21 ,  C12N15/31 ,  C12P13/08 ,  C12P21/06

    CPC分类号： C07K14/34 ,  C12P13/08

    摘要： The present invention relates to polynucleotides corresponding to the luxR gene and which encode a LuxR transcriptional activator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LuxR transcriptional activation activity. The invention also relates to isolating the luxR gene and which encode a LuxR transcriptional activator from Corynebacterium glutamicum.

    摘要翻译： 本发明涉及对应于luxR基因并编码LuxR转录激活剂的多核苷酸，产生L-氨基酸的方法，以及筛选编码具有LuxR转录活化活性的蛋白质的多核苷酸的方法。 本发明还涉及分离luxR基因，其编码来自谷氨酸棒杆菌的LuxR转录激活物。