DETECTION KIT FOR IDENTIFYING GENOTYPE IN DEPRESSION PATIENTS AND METHOD OF USING THE SAME
    12.
    发明申请
    DETECTION KIT FOR IDENTIFYING GENOTYPE IN DEPRESSION PATIENTS AND METHOD OF USING THE SAME 审中-公开
    用于鉴定抑郁症患者基因组的检测工具及其使用方法

    公开(公告)号:US20140162261A1

    公开(公告)日:2014-06-12

    申请号:US14091575

    申请日:2013-11-27

    IPC分类号: C12Q1/68

    摘要: The present invention relates to a rs6311 test kit, which includes a probe, a primer, and a polymerase chain reaction solution, wherein said probe sequence is as follows: rs6311T-fam: CTGTGAGTGTCTGGC (SEQ. ID. NO. 1) and rs6311C-vic: CTGTGAGTGTCCGGC (SEQ. ID. NO. 2); and said primer sequence is as follows: rs6311-F: AGAGAGAACATAAATAAGGCTAGAAAACAGTA (SEQ. ID. NO. 3) and rs6311-R: CACTGTTGGCTTTGGATGGA (SEQ. ID. NO. 4). The test kit is used to determine genotype of a depression patient, in order to treat the depression patient with a combination of serotonin reuptake inhibitors (SSRI) and low dose risperidone. The actual dose of risperidone and the ratio between SSRIs and risperidone is determined by the genotype of the depression patient. The present invention determines human drug metabolism rate through a single nucleotide polymorphism and provides a platform to adjust the patient's treatment.

    摘要翻译: 本发明涉及一种rs6311测试试剂盒,其包括探针,引物和聚合酶链反应溶液,其中所述探针序列如下:rs6311T-fam:CTGTGAGTGTCTGGC(SEQ ID NO:1)和rs6311C- vic:CTGTGAGTGTCCGGC(SEQ ID NO:2); 并且所述引物序列如下:rs6311-F:AGAGAGAACATAAATAAGGCTAGAAAACAGTA(SEQ ID NO:3)和rs6311-R:CACTGTTGGCTTTGGATGGA(SEQ ID NO:4)。 测试试剂盒用于确定抑郁症患者的基因型,以便用5-羟色胺再摄取抑制剂(SSRI)和低剂量利培酮组合治疗抑郁症患者。 利培酮的实际剂量和SSRI和利培酮之间的比例由抑郁症患者的基因型决定。 本发明通过单核苷酸多态性测定人体药物代谢率,提供调整患者治疗的平台。

    Method and apparatus for updating inter-server communication software
    13.
    发明授权
    Method and apparatus for updating inter-server communication software 有权
    更新服务器间通信软件的方法和装置

    公开(公告)号:US07228539B2

    公开(公告)日:2007-06-05

    申请号:US10462477

    申请日:2003-06-16

    IPC分类号: G06F9/44 G06F15/177

    CPC分类号: G06F8/656

    摘要: A method and apparatus for updating inter-server communication software in a network are provided. More particularly, the invention is directed to a technique for software updating of servers that reduces the unavailability of network resources due to the update process. In this regard, the method includes the implementation of proxy software in servers that are to be updated. The servers are then selectively updated (e.g. one server at a time) in a manner, using the proxy software, to allow the servers to communicate with one another during the entire update process.

    摘要翻译: 提供了一种用于在网络中更新服务器间通信软件的方法和装置。 更具体地,本发明涉及一种用于软件更新服务器的技术,其减少了由于更新过程而导致的网络资源的不可用性。 在这方面,该方法包括在要更新的服务器中实现代理软件。 然后,使用代理软件,可以在整个更新过程中使服务器彼此进行通信,从而有选择地更新服务器(例如,一次一个服务器)。