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公开(公告)号：US20180094274A1
公开(公告)日：2018-04-05
申请号：US15627006
申请日：2017-06-19
发明人： Christoph Benning , John B. Ohlrogge , Wei Ma , Que Kong
IPC分类号： C12N15/82
摘要： The application describes plants, plant cells, and seeds that express WRINKLED1 transcription factors and/or 14-3-3 proteins that are useful for increasing production of oils in plants and seeds. Also described are expression systems and cassettes that encode and express such WRINKLED1 transcription factors and/or 14-3-3 proteins.
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公开(公告)号：US20170218386A1
公开(公告)日：2017-08-03
申请号：US15487063
申请日：2017-04-13
发明人： Christoph Benning , Sanjaya
CPC分类号： C12N15/8247 , C07K14/415 , C12N15/8218 , C12N15/8245 , C12Y207/07027
摘要： The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.
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13.发明授权Method to increase algal biomass and enhance its quality for the production of fuel 有权增加藻类生物量并提高其生产燃料质量的方法公开(公告)号：US09315838B2
公开(公告)日：2016-04-19
申请号：US14073959
申请日：2013-11-07
发明人： Christoph Benning , Xiaobo Li , Bensheng Liu , Min-Hao Kuo , Barbara Sears
CPC分类号： C12P7/6463 , C12N15/8247 , Y02E50/13
摘要： The invention provides a recombinant cell having a nucleotide sequence encoding a polypeptide which is a lipase having at least 40% amino acid sequence identity to a polypeptide having SEQ ID NO:1, and methods of using the recombinant cell to produce triacylglycerols or to increase oil production by the cell.
摘要翻译： 本发明提供了具有编码多肽的核苷酸序列的重组细胞，该多肽是与具有SEQ ID NO：1的多肽具有至少40％氨基酸序列同一性的脂肪酶，以及使用该重组细胞产生三酰基甘油或增加油的方法 由细胞生产。
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公开(公告)号：US20150376660A1
公开(公告)日：2015-12-31
申请号：US14746680
申请日：2015-06-22
CPC分类号： C12P7/6463 , C12N9/1029 , C12N15/79 , C12N15/8247 , C12P7/6409 , C12Y203/0102
摘要： The present invention is related to biosynthetic oil compositions and methods of making thereof. In some embodiments, the invention relates to the use of endogenous enzymes in plants capable of synthesizing oil. In preferred embodiments, said plants are algae. In further embodiments, said algae are from the family Chlamydomonas, Nannochloropsis, Dunaliella, Chiarella and Scenedesmus. In still further embodiments, said endogenous enzymes are diacylglycerol acyltransferases.
摘要翻译： 本发明涉及生物合成油组合物及其制备方法。 在一些实施方案中，本发明涉及内源性酶在能够合成油的植物中的用途。 在优选的实施方案中，所述植物是藻类。 在另外的实施方案中，所述藻类来自衣藻，南非氯氰菊酯，杜氏藻属，赤霉病菌属和Scenedesmus。 在另外的实施方案中，所述内源酶是二酰基甘油酰基转移酶。
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公开(公告)号：US20200040351A1
公开(公告)日：2020-02-06
申请号：US16498663
申请日：2018-03-29
发明人： Christoph Benning , Kun Wang
摘要： Described herein are transgenic plants with increased oil content that exhibit enhanced expression of plastid-specific lipases (e.g., PLIP1). The manufacture of lipids can be enhanced by expression of FAD4.
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公开(公告)号：US10006039B2
公开(公告)日：2018-06-26
申请号：US14046504
申请日：2013-10-04
发明人： Christoph Benning , Sanjaya , Changcheng Xu
IPC分类号： C12N15/82 , C07K14/415 , C12N9/12 , C12N9/14
CPC分类号： C12N15/8247 , C07K14/415 , C12N9/1241 , C12N9/14 , C12N15/8218 , C12Y207/07027 , C12Y306/03
摘要： The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.
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17.发明申请REGULATOR OF ALGAL LIPID METABOLISM AND CELLULAR QUIESCENCE AND ITS APPLICATIONS 审中-公开碱性脂质代谢和细胞因子及其应用的调节剂公开(公告)号：US20160201075A1
公开(公告)日：2016-07-14
申请号：US14874079
申请日：2015-10-02
发明人： Christoph Benning , Chia-Hong Tsai
CPC分类号： C12N15/8247 , C07K14/415 , C12P7/6463
摘要： Provided herein is a mutant algae that produces increased oil, especially when exposed to nutrient deprivation. The mutation is at a CHT7 locus, which is wild type cells encodes a protein that affects turnover of oils and the transition of algal cells from quiescence to normal growth.
摘要翻译： 本文提供了产生增加的油的突变藻类，特别是当暴露于营养物质剥夺时。 该突变位于CHT7基因座，其是野生型细胞，其编码影响油的转换和藻细胞从静止转变为正常生长的蛋白质。
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公开(公告)号：US20130212736A1
公开(公告)日：2013-08-15
申请号：US13719868
申请日：2012-12-19
CPC分类号： C12P7/6463 , C12N9/1029 , C12N15/79 , C12N15/8247 , C12P7/6409 , C12Y203/0102
摘要： The present invention is related to biosynthetic oil compositions and methods of making thereof. In some embodiments, the invention relates to the use of endogenous enzymes in plants capable of synthesizing oil. In preferred embodiments, said plants are algae. In further embodiments, said algae are from the family Chlamydomonas, Nannochloropsis, Dunaliella, Chiarella and Scenedesmus. In still further embodiments, said endogenous enzymes are diacylglycerol acyltransferases.
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19.发明申请公开(公告)号：US20210395763A1
公开(公告)日：2021-12-23
申请号：US17266133
申请日：2019-08-08
IPC分类号： C12N15/82 , C07K14/415
摘要： Methods and expression systems are described herein that are useful for production of terpenes and terpenoids.
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公开(公告)号：US10822583B2
公开(公告)日：2020-11-03
申请号：US15894457
申请日：2018-02-12
发明人： Gregory Bonito , Zhi-Yan Du , Christoph Benning
摘要： This application describes consortium between fungi and algae, where the algae are incorporated within hyphae of the fungi. The consortium is robust. The fungi and algae can symbiotically provide nutrients to each other, and are tolerant of environmental stresses.
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