公开(公告)号：US08529907B2

公开(公告)日：2013-09-10

申请号：US12989817

申请日：2009-04-27

申请人： Michael Belkin ,  Aviv Shaish ,  Dror Harats ,  Ygal Rotenstreich

发明人： Michael Belkin ,  Aviv Shaish ,  Dror Harats ,  Ygal Rotenstreich

IPC分类号： A61K36/05 ,  A61P27/02

CPC分类号： A61K36/05

摘要： Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided.

摘要翻译： 提供了一种在患有视网膜疾病或创伤的受试者中改善日视觉和/或锥形视野和视觉功能的方法，包括向受试者施用药学有效量的粗制杜氏盐藻粉。 还提供了一种在患有视网膜疾病的受试者中改善夜视和/或杆状视野的方法，包括向受试者施用药学有效量的粗制杜氏盐藻粉。 还提供了用于改善患有视网膜疾病，包括粗制杜氏盐藻粉末的受试者的日视力和/或视野的药物组合物。

公开(公告)号：US06761694B2

公开(公告)日：2004-07-13

申请号：US10016036

申请日：2001-12-13

申请人： Robert David ,  Michael Belkin

发明人： Robert David ,  Michael Belkin

IPC分类号： A61B1300

CPC分类号： A61B3/1005

摘要： Methods for measuring retinal damage resulting from an injury include calculating the slope of retinal thickness from the injury site to the periphery of the site. A shallower slope of retinal thickness correlates with a greater degree of damage resulting from the injury. The methods may also be useful to screen pharmaceuticals for potential neuroprotective effects against retinal injuries.

摘要翻译： 用于测量由损伤引起的视网膜损伤的方法包括计算视网膜厚度从损伤位点到位点周边的斜率。 视网膜厚度较浅的斜率与损伤造成的损伤程度相关。 该方法也可用于筛选药物以对视网膜损伤的潜在神经保护作用。

公开(公告)号：US5620435A

公开(公告)日：1997-04-15

申请号：US539246

申请日：1995-10-05

申请人： Michael Belkin ,  Abraham Katzir ,  Alon Goldring ,  Alex Harel ,  Yeshayahu S. Eisenberg

发明人： Michael Belkin ,  Abraham Katzir ,  Alon Goldring ,  Alex Harel ,  Yeshayahu S. Eisenberg

IPC分类号： A61B17/00 ,  A61F9/008 ,  A61N5/06

CPC分类号： A61F9/00825 ,  A61B17/00491 ,  A61F9/008 ,  A61F9/0081 ,  A61B2017/00508 ,  A61F2009/00863 ,  A61F2009/00865 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887 ,  A61F2009/00889 ,  A61F9/00831

摘要： A method for welding ocular tissues to each other including providing a first portion of ocular tissue having a leading edge and a second portion of ocular tissue having a leading edge, positioning the leading edge of the first portion of ocular tissue directly adjacent to and against the leading edge of the second portion of ocular tissue, and applying pulses of a laser light from a source thereof substantially simultaneously to the leading edge of the first portion of ocular tissue and to the leading edge of the second portion of ocular tissue, the pulses of the laser light penetrating the portions of ocular tissue to a depth of approximately 1-300 microns so that the leading edge of the first portion of ocular tissue may be securely welded to the leading edge of the second portion of ocular tissue, the laser light having a wavelength of approximately 10.6 microns and a power output level sufficient to maintain the portions of ocular tissue at a temperature of approximately 45-60 degrees Celsius during the applying of the laser light.

摘要翻译： 一种用于将眼组织彼此焊接的方法，包括提供具有前缘的眼组织的第一部分和具有前缘的眼组织的第二部分，将眼组织的第一部分的前缘直接邻近并抵靠眼组织 眼组织的第二部分的前缘，并且将来自其源的激光的脉冲基本上同时施加到眼组织的第一部分的前缘和眼组织的第二部分的前缘，脉冲 所述激光穿透眼组织的部分至约1-300微米的深度，使得眼组织的第一部分的前缘可以牢固地焊接到眼组织的第二部分的前缘，激光具有 约10.6微米的波长和足以将眼部组织的部分维持在大约45-60度的温度的功率输出水平 在施加激光时的里氏摄氏度。

公开(公告)号：US09668672B2

公开(公告)日：2017-06-06

申请号：US13564381

申请日：2012-08-01

申请人： Zeev Zalevsky ,  Javier Garcia ,  Vincente Mico ,  Michael Belkin ,  Yevgeny Biederman ,  Israel Margalit

发明人： Zeev Zalevsky ,  Javier Garcia ,  Vincente Mico ,  Michael Belkin ,  Yevgeny Biederman ,  Israel Margalit

IPC分类号： A61B5/00 ,  A61B5/1455 ,  A61B5/08 ,  A61B5/145 ,  A61B3/00 ,  A61B3/10 ,  A61B5/01 ,  A61B5/02 ,  A61B5/024 ,  A61B5/026 ,  A61B5/0295 ,  A61B3/16

CPC分类号： A61B5/0803 ,  A61B3/0008 ,  A61B3/102 ,  A61B3/16 ,  A61B3/165 ,  A61B5/0066 ,  A61B5/0077 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/02028 ,  A61B5/02035 ,  A61B5/0205 ,  A61B5/02133 ,  A61B5/0215 ,  A61B5/02416 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/0816 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/442 ,  A61B5/4504 ,  A61B5/4875 ,  A61B5/72 ,  A61B5/7278

摘要： A system and method are presented for use in monitoring one or more conditions of a subject's body. The system includes a control unit which includes an input port for receiving image data, a memory utility, and a processor utility. The image data is indicative of data measured by a pixel detector array and is in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern. The memory utility stores one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body. The processor utility is configured and operable for processing the image data to determine one or more corresponding body conditions; and generating output data indicative of the corresponding body conditions.

公开(公告)号：US20110045035A1

公开(公告)日：2011-02-24

申请号：US12989817

申请日：2009-04-27

申请人： Michael Belkin ,  Aviv Shaish ,  Dror Harats ,  Ygal Rotenstreich

发明人： Michael Belkin ,  Aviv Shaish ,  Dror Harats ,  Ygal Rotenstreich

IPC分类号： A61K36/05 ,  A61P27/02 ,  A61K9/00 ,  A61P9/10

CPC分类号： A61K36/05

摘要： Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided.

摘要翻译： 提供了一种在患有视网膜疾病或创伤的受试者中改善日视觉和/或锥形视野和视觉功能的方法，包括向受试者施用药学有效量的粗制杜氏盐藻粉。 还提供了一种在患有视网膜疾病的受试者中改善夜视和/或杆状视野的方法，包括向受试者施用药学有效量的粗制杜氏盐藻粉。 还提供了用于改善患有视网膜疾病，包括粗制杜氏盐藻粉末的受试者的日视力和/或视野的药物组合物。