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公开(公告)号：US10479802B2
公开(公告)日：2019-11-19
申请号：US15507208
申请日：2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Samuel Coe , Jonathan Bard , Peter David Johnson , Michael Edward Prime , Christopher John Brown , Sébastien René Gabriel Galan , Paul Richard Giles , Elise Luciennen Paulette Gadouleau , Thomas Martin Krülle , Daniel Clark-Frew , John Wityak , Alex Kiselyov , Sarah Hayes
IPC: C07D513/04 , C07D413/14 , C07D471/04 , A61K51/04 , C07D413/12 , C07D263/57 , C07D498/04 , C07D405/14 , C07D413/04
Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20170283439A1
公开(公告)日：2017-10-05
申请号：US15507203
申请日：2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel CLark-Frew
IPC: C07D519/00 , A61K51/04 , C07D471/04
CPC classification number: C07D519/00 , A61K51/0455 , A61K51/0459 , C07D471/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US11104691B2
公开(公告)日：2021-08-31
申请号：US15507203
申请日：2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel Clark-Frew
IPC: A61K51/00 , A61M36/14 , C07D519/00 , C07D471/04 , A61K51/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10765764B2
公开(公告)日：2020-09-08
申请号：US16172425
申请日：2018-10-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20200276176A1
公开(公告)日：2020-09-03
申请号：US16799651
申请日：2020-02-24
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Jonathan Bard , Matthew R. Lee , Longbin Liu , Michael Edward Prime , Samuel Coe
IPC: A61K31/454 , A61K31/427 , A61K31/165 , A61K47/54
Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
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Patent Agency Ranking
公开(公告)号：US20190167821A1
公开(公告)日：2019-06-06
申请号：US16172425
申请日：2018-10-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07B59/00 , C07D513/04 , C07D487/04 , C07D513/14
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10137211B2
公开(公告)日：2018-11-27
申请号：US15249223
申请日：2016-08-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use
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公开(公告)号：US20170281804A1
公开(公告)日：2017-10-05
申请号：US15507214
申请日：2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Thomas Martin Krülle , Daniel Clark-Frew , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D513/14 , C07D487/04
CPC classification number: A61K51/0455 , C07B2200/05 , C07D401/04 , C07D401/14 , C07D403/04 , C07D487/04 , C07D513/04 , C07D513/14
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US12036291B2
公开(公告)日：2024-07-16
申请号：US17353611
申请日：2021-06-21
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Thomas Martin Krülle , Daniel Clark-Frew , Sarah Hayes
IPC: A61K51/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D487/04 , C07D513/04 , C07D513/14
CPC classification number: A61K51/0455 , C07D401/04 , C07D401/14 , C07D403/04 , C07D487/04 , C07D513/04 , C07D513/14 , C07B2200/05
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US11851446B2
公开(公告)日：2023-12-26
申请号：US17353627
申请日：2021-06-21
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel Clark-Frew
IPC: C07D519/00 , C07D471/04 , A61K51/04
CPC classification number: C07D519/00 , A61K51/0455 , A61K51/0459 , C07D471/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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