公开(公告)号：US20220339302A1

公开(公告)日：2022-10-27

申请号：US17715661

申请日：2022-04-07

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Celia Dominguez ,  Jonathan Bard ,  Christopher John Brown ,  Xuemei Chen ,  Daniel Clark-Frew ,  Matthew Robert Mills ,  Peter David Johnson ,  Elise Gadouleau

IPC: A61K51/04 ,  A61P25/28 ,  C07D401/14

Abstract: Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.

公开(公告)号：US20210393812A1

公开(公告)日：2021-12-23

申请号：US17344582

申请日：2021-06-10

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Matthew Lee ,  Celia Dominguez ,  Peter David Johnson ,  Catherine Jane Greenaway ,  Kanika Khurana ,  Matthew Robert Mills ,  Filippo Rota

IPC: A61K51/04 ,  C07B59/00 ,  C07D487/04 ,  C07D487/14 ,  C07D519/00 ,  C07D231/12 ,  C07D471/04

Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.