公开(公告)号：US20220339302A1

公开(公告)日：2022-10-27

申请号：US17715661

申请日：2022-04-07

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Celia Dominguez ,  Jonathan Bard ,  Christopher John Brown ,  Xuemei Chen ,  Daniel Clark-Frew ,  Matthew Robert Mills ,  Peter David Johnson ,  Elise Gadouleau

IPC: A61K51/04 ,  A61P25/28 ,  C07D401/14

Abstract: Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.

公开(公告)号：US12036292B2

公开(公告)日：2024-07-16

申请号：US17395055

申请日：2021-08-05

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Celia Dominguez ,  Xuemei Chen ,  John E. Mangette

IPC: A61K51/04 ,  C07D239/28 ,  C07D401/12 ,  C07D401/14 ,  C07D403/06 ,  C07D471/04

CPC classification number: A61K51/0459 ,  C07D239/28 ,  C07D401/12 ,  C07D401/14 ,  C07D403/06 ,  C07D471/04 ,  C07B2200/05

Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.