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公开(公告)号：US20170342382A1
公开(公告)日：2017-11-30
申请号：US15602819
申请日：2017-05-23
Applicant: Corning Incorporated
Inventor： Huayun Deng , Ye Fang , Qiang Fu , John Christopher Mauro
CPC classification number: C12N5/0654 , A61K35/32 , A61L27/105 , A61L27/54 , A61L2300/102 , C03C3/19 , C03C4/0014 , C03C4/0035 , C03C2204/00 , C12N2501/105 , C12N2501/11 , C12N2501/115 , C12N2501/165 , C12N2533/12
Abstract: An aluminoborate glass composition, including B2O3, Al2O3, P2O5, Na2O, and CaO, as defined herein. Also disclosed are bioactive compositions including the disclosed aluminoborate glass composition, a suitable fluid, and at least one live cell. Also disclosed is method of limiting the amount of boron released into an aqueous solution from a disclosed aluminoborate-containing glass composition as defined herein. Also disclosed is a method of proliferating cells on a bioactive substrate as defined herein.
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12.发明申请USE OF LABEL-FREE BIOSENSORS TO UNDERSTAND AND IDENTIFY TREATMENT FOR CANCER 审中-公开无标签生物传感器的使用了解癌症和癌症鉴定公开(公告)号：US20130210057A1
公开(公告)日：2013-08-15
申请号：US13767142
申请日：2013-02-14
Applicant: CORNING INCORPORATED
Inventor： Huayun Deng , Ye Fang , Joydeep Lahiri , Shizhang Ling
IPC: C12Q1/02
CPC classification number: C12Q1/025 , G01N33/5011 , G01N33/54373 , G01N2333/726
Abstract: The disclosure relates to methods of using dynamic mass redistribution data obtained from cancer cells cultured on waveguide grating biosensors in the presence of agonists and in the presence of chemotherapeutic agents, for predicting effective chemotherapies for the treatment of cancer.
Abstract translation: 本公开涉及使用在激动剂存在下和在化学治疗剂存在下在波导光栅生物传感器上培养的癌细胞获得的动态质量再分布数据的方法，用于预测用于治疗癌症的有效化学疗法。
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公开(公告)号：US11274059B2
公开(公告)日：2022-03-15
申请号：US16203002
申请日：2018-11-28
Applicant: CORNING INCORPORATED
Inventor： Huayun Deng , Ye Fang , Qiang Fu , John Christopher Mauro , Michael S Pambianchi
IPC: A61K6/00 , A61K33/06 , A61K8/25 , A61K31/69 , C03C3/19 , C03C3/064 , C03C3/087 , C03C3/091 , C03C3/097 , A61Q11/00 , C03C4/00 , A61K8/21 , A61K8/19 , A61K8/26 , A61K6/20 , A61K6/77 , A61K6/836
Abstract: A dental formulation including: a bioactive glass composition as defined herein, in an effective amount; and a suitable carrier as defined herein, in an effective amount. Also disclosed is a method of making and using the dental formulation to treat, for example, dentin sensitivities.
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公开(公告)号：US11198638B2
公开(公告)日：2021-12-14
申请号：US16202873
申请日：2018-11-28
Applicant: CORNING INCORPORATED
Inventor： Huayun Deng , Qiang Fu , Ying Wei
IPC: C03C4/00 , A61K8/28 , C03C3/21 , A61K8/24 , A61Q11/00 , A61P43/00 , C03C3/19 , C03C3/247 , A61K8/21 , A61K33/42 , A61K33/08 , A61K33/22 , A61K6/20 , A61K6/818 , A61K6/833 , A61K6/836
Abstract: A bioactive borate glass composition including, for example: 30 to 60% B2O3; 0.5 to 20% ZrO2; 3 to 30% Na2O; 0.1 to 15% K2O; 0.1 to 15% MgO; 5 to 30% CaO; and 1 to 5% P2O5 in mole percents based on 100 mol % of the total composition. Also disclosed is a method of making and method of using the compositions and the bioactive borate glass dentin treatment formulations.
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公开(公告)号：US20210341838A1
公开(公告)日：2021-11-04
申请号：US17283418
申请日：2019-10-09
Applicant: Corning Incorporated
Inventor： Huayun Deng , Mingqian He , Jenny Kim , Xin Li , Yang Li , Weijun Niu , Arthur Lawrence Wallace , Hongxiang Wang
Abstract: A polymer blend includes at least one organic semiconductor (OSC) polymer, at least one crosslinker, and at least one photoinitiator, such that the at least one OSC polymer is a diketopyrrolopyrrole-fused thiophene polymeric material, the fused thiophene being beta-substituted, and such that the crosslinker includes at least one of: acrylates, epoxides, oxetanes, alkenes, alkynes, azides, thiols, allyloxysilanes, phenols, anhydrides, amines, cyanate esters, isocyanate esters, silyl hydrides, cinnamates, coumarins, fluorosulfates, silyl ethers, or a combination thereof.
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Patent Agency Ranking
16.发明申请公开(公告)号：US20200061193A1
公开(公告)日：2020-02-27
申请号：US16611015
申请日：2018-05-07
Applicant: CORNING INCORPORATED
Inventor： Theresa Chang , Huayun Deng , Benjamin Leonard Linchuck , Ying Wei , Ying Zhang , Yue Zhou
Abstract: Cross-linked shear-thinning fluids of pectic acid demonstrating increased viscosity with decreasing shear, as well as methods of producing and using the same. A shear-thinning fluid includes an aqueous solution of pectic acid cross-linked by a divalent cation is disclosed. The pectic acid may be present in an amount ranging from about 0.5 to about 3.0% (w/v), the divalent cation may be present at a concentration of from about 0.5 mM to about 7.0 mM, and the viscosity of the shear-thinning fluid increases with decreasing shear. These cross-linked shear-thinning fluids of pectic acid can be utilized for controlled release formulations, cell encapsulation, and 3D printing, and provide for an improved balance between structure fidelity/mechanical stability and cell viability.
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公开(公告)号：US20190161393A1
公开(公告)日：2019-05-30
申请号：US16203002
申请日：2018-11-28
Applicant: CORNING INCORPORATED
Inventor： Huayun Deng , Ye Fang , Qiang Fu , John Christopher Mauro , Michael S. Pambianchi
Abstract: A dental formulation including: a bioactive glass composition as defined herein, in an effective amount; and a suitable carrier as defined herein, in an effective amount. Also disclosed is a method of making and using the dental formulation to treat, for example, dentin sensitivities.
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公开(公告)号：US20190160201A1
公开(公告)日：2019-05-30
申请号：US16202786
申请日：2018-11-28
Applicant: CORNING INCORPORATED
Inventor： Huayun Deng , Qiang Fu , John Christopher Mauro
IPC: A61L27/10 , C03C10/00 , C03C10/16 , C03C4/00 , C03C4/18 , A61L24/02 , A61L24/00 , A61L27/12 , A61L27/04 , A61L27/02
Abstract: A chemically strengthened bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.
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公开(公告)号：US20190048318A1
公开(公告)日：2019-02-14
申请号：US16163013
申请日：2018-10-17
Applicant: Corning Incorporated
Inventor： Huayun Deng , Qiang Fu , John Christopher Mauro
Abstract: A bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.
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公开(公告)号：US20170340666A1
公开(公告)日：2017-11-30
申请号：US15603208
申请日：2017-05-23
Applicant: Corning Incorporated
Inventor： Huayun Deng , Ye Fang , Qiang Fu , Lina Ma , John Christopher Mauro , Michael Joshua Snyder , Dana Lynne Widmer-Quiel
CPC classification number: A61K33/42 , A61L15/18 , A61L15/44 , A61L26/0004 , A61L26/0066 , C03B19/102 , C03C3/064 , C03C3/19 , C03C4/0007 , C03C4/0014 , C03C11/002 , C03C12/00
Abstract: An aluminoborate composition, an alumino-borosilicate glass composition, or a mixture thereof, and solid or hollow microspheres thereof, as defined herein. Also disclosed are methods of making and using the disclosed compositions, for example, forming microspheres for use in bioactive applications, and composition extracts for use in treating or healing wounds.
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