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公开(公告)号：US08241274B2
公开(公告)日：2012-08-14
申请号：US12570888
申请日：2009-09-30
申请人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
发明人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
IPC分类号： A61B18/04
CPC分类号： A61F2/2496 , A61B5/0044 , A61B5/1076 , A61B5/6853 , A61B8/445 , A61B18/1442 , A61B34/20 , A61B90/37 , A61B90/39 , A61B2017/00243 , A61B2018/00291 , A61B2018/00351 , A61B2018/00577 , A61B2034/2051 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61F2/2433 , A61F2210/009 , A61F2250/0096 , A61N7/02
摘要： A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect of the invention, a delivery system is provided for percutaneous delivery of a heart valve to a predetermined position in the heart of a patient, where the delivery system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a delivery system is provided for percutaneous repair of a heart valve in the heart of a patient, where the repair system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality.
摘要翻译： 公开了一种用于瓣膜置换或瓣膜修复的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪位置的同时引导患者内的瓣膜置换输送构件或瓣膜修复递送构件 的患者中的输送构件，将瓣膜置换构件或瓣膜修复构件定位在期望的位置以放置瓣膜或修复瓣膜并从患者移除输送构件。 在本发明的一个方面，提供一种用于将心脏瓣膜经皮递送到患者心脏中的预定位置的递送系统，其中递送系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供一种用于经皮修复患者心脏中的心脏瓣膜的递送系统，其中所述修复系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供了一种方法和装置，其涉及使用手术技术对本地根进行成像，然后引入在选择的成像模式中容易可视化的装置。
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公开(公告)号：US20090254165A1
公开(公告)日：2009-10-08
申请号：US12358789
申请日：2009-01-23
申请人： Charles Tabor , Timothy R. Ryan
发明人： Charles Tabor , Timothy R. Ryan
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2/844 , A61F2002/9505 , A61F2002/9511 , A61F2002/9522 , A61F2002/9665 , A61F2250/0098
摘要： A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
摘要翻译： 一种用于将可植入支架装置输送到患者的内腔的输送系统，所述输送系统包括具有近端和远端的细长主体，位于所述细长体近端的驱动器机构，位于 以及护套，其包括具有中空内部部分的细长管状部分，第一直径的尺寸适于将可植入支架装置压缩和保持在压缩构型中以输送到体腔。
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公开(公告)号：US20090198316A1
公开(公告)日：2009-08-06
申请号：US12357980
申请日：2009-01-22
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.
摘要翻译： 一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合 结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后 将支架装置的第二结构元件与第二支架接合结构分离。
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14.发明授权公开(公告)号：US08685077B2
公开(公告)日：2014-04-01
申请号：US13420101
申请日：2012-03-14
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A delivery system with sequential release mechanism and method of delivering and deploying an implantable stented device into a body lumen including a tabular body, a plurality of activation members extending from the distal end of the tubular body, and a plurality of disks. Each disk includes a proximal and distal surface, at least one stent engagement element attached to the distal surface of the disk and at least one aperture. At least one activation member attaches to the proximal surface of a first disk and at least one activation member passes through an aperture of the first disk and attaches to the proximal surface of a second disk. At least one stent engagement element attached to the distal surface of the first disk passes through an aperture of the second disk. Axially movement of the activation members causes sequential release of the stent engagement elements from a stented device.
摘要翻译： 具有顺序释放机构的递送系统和将可植入支架装置递送和展开到体腔内的方法，该体腔包括片状体，从管状体的远端延伸的多个致动构件和多个盘。 每个盘包括近端和远端表面，至少一个支架接合元件附接到盘的远端表面和至少一个孔。 至少一个激活构件附接到第一盘的近侧表面，并且至少一个激活构件穿过第一盘的孔并附接到第二盘的近侧表面。 附接到第一盘的远端表面的至少一个支架接合元件通过第二盘的孔。 致动构件的轴向移动导致支架接合元件从支架装置的顺序释放。
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15.发明授权公开(公告)号：US08157852B2
公开(公告)日：2012-04-17
申请号：US12357958
申请日：2009-01-22
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end and a distal end, and a plurality of wires extending from the distal end of the tubular body, wherein each of the wires has a distal end that is coiled for engagement with a stent of a stented prosthetic heart valve.
摘要翻译： 一种用于将支架假体心脏瓣膜输送到患者的内腔的输送系统，所述输送系统包括具有近端和远端的管状体以及从所述管状体的远端延伸的多根线，其中每个 的线具有被卷绕以与支架假体心脏瓣膜的支架接合的远端。
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公开(公告)号：US20090192591A1
公开(公告)日：2009-07-30
申请号：US12358765
申请日：2009-01-23
申请人： Timothy R. Ryan , Charles Tabor
发明人： Timothy R. Ryan , Charles Tabor
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A replacement prosthetic heart valve for engagement with a structure of an original prosthetic heart valve that includes at least one visually detectable marker. The replacement heart valve includes a stent structure having a generally tubular body portion and at least one visually detectable marker on a portion of the stent structure, and at least two leaflets attached within the interior area of the tubular body portion of the stent structure. At least one visually detectable marker of the stent structure is alignable with at least one visually detectable marker of the original prosthetic heart valve.
摘要翻译： 一种替换假体心脏瓣膜，用于与包括至少一个视觉上可检测的标记物的原始假体心脏瓣膜的结构接合。 置换心脏瓣膜包括支架结构，该支架结构具有大致管状主体部分和在支架结构的一部分上的至少一个视觉上可检测的标记，以及附接在支架结构的管状主体部分的内部区域内的至少两个小叶。 支架结构的至少一个视觉上可检测的标记可与原始假体心脏瓣膜的至少一个视觉上可检测的标记物对准。
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公开(公告)号：US09089422B2
公开(公告)日：2015-07-28
申请号：US12358765
申请日：2009-01-23
申请人： Timothy R. Ryan , Charles Tabor
发明人： Timothy R. Ryan , Charles Tabor
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A replacement prosthetic heart valve for engagement with a structure of an original prosthetic heart valve that includes at least one visually detectable marker. The replacement heart valve includes a stent structure having a generally tubular body portion and at least one visually detectable marker on a portion of the stent structure, and at least two leaflets attached within the interior area of the tubular body portion of the stent structure. At least one visually detectable marker of the stent structure is alignable with at least one visually detectable marker of the original prosthetic heart valve.
摘要翻译： 一种替换假体心脏瓣膜，用于与包括至少一个视觉上可检测的标记物的原始假体心脏瓣膜的结构接合。 置换心脏瓣膜包括支架结构，该支架结构具有大致管状主体部分和在支架结构的一部分上的至少一个视觉上可检测的标记，以及附接在支架结构的管状主体部分的内部区域内的至少两个小叶。 支架结构的至少一个视觉上可检测的标记可与原始假体心脏瓣膜的至少一个视觉上可检测的标记物对准。
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18.发明授权公开(公告)号：US09393115B2
公开(公告)日：2016-07-19
申请号：US12358789
申请日：2009-01-23
申请人： Charles Tabor , Timothy R. Ryan
发明人： Charles Tabor , Timothy R. Ryan
CPC分类号： A61F2/966 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2/844 , A61F2002/9505 , A61F2002/9511 , A61F2002/9522 , A61F2002/9665 , A61F2250/0098
摘要： A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.
摘要翻译： 一种用于将可植入支架装置输送到患者的内腔的输送系统，所述输送系统包括具有近端和远端的细长主体，位于所述细长体近端的驱动器机构，位于 以及护套，其包括具有中空内部部分的细长管状部分，第一直径的尺寸适于将可植入支架装置压缩和保持在压缩构型中以输送到体腔。
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19.发明授权公开(公告)号：US08157853B2
公开(公告)日：2012-04-17
申请号：US12357980
申请日：2009-01-22
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.
摘要翻译： 一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合 结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后 将支架装置的第二结构元件与第二支架接合结构分离。
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20.发明申请公开(公告)号：US20090287290A1
公开(公告)日：2009-11-19
申请号：US12358084
申请日：2009-01-22
申请人： Patrick E. Macaulay , Robert J. Murray , Trevor Greenan , Timothy R. Ryan , Charles Tabor , Matthew J. Birdsall , Gianfranco Pellegrini
发明人： Patrick E. Macaulay , Robert J. Murray , Trevor Greenan , Timothy R. Ryan , Charles Tabor , Matthew J. Birdsall , Gianfranco Pellegrini
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2002/9505 , A61F2002/9511 , A61F2002/9534 , A61F2002/9665 , A61F2250/0098
摘要： A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end, a distal end, and a base portion with a plurality of extending elements, wherein each of the extending elements is engageable with a portion of a stent of a prosthetic heart valve. The delivery system further includes a sleeve having an inner area. The sheath is longitudinally moveable relative to the base portion from a first position where the inner area of the sleeve at least partially covers the extending elements of the base portion to a second position where the extending elements are not positioned within the inner area of the sleeve.
摘要翻译： 一种用于将支架假体心脏瓣膜递送到患者的内腔的输送系统，所述输送系统包括具有近端，远端和具有多个延伸元件的基部的管状体，其中每个所述延伸元件 可与假体心脏瓣膜的支架的一部分接合。 输送系统还包括具有内部区域的套筒。 护套从第一位置可相对于基部纵向移动，其中套筒的内部区域至少部分地将基部的延伸元件覆盖到第二位置，在第二位置，延伸元件不位于套筒的内部区域内 。
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