公开(公告)号：US08852271B2

公开(公告)日：2014-10-07

申请号：US13095117

申请日：2011-04-27

申请人： Robert J. Murray, III ,  Jason Kolden ,  Jeffery Argentine

发明人： Robert J. Murray, III ,  Jason Kolden ,  Jeffery Argentine

IPC分类号： A61F2/84 ,  A61F2/966 ,  A61F2/24 ,  A61F2/95

CPC分类号： A61F2/2418 ,  A61F2/2436 ,  A61F2/966 ,  A61F2002/9505 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0054 ,  A61F2230/008

摘要： A delivery system for percutaneously delivering and deploying a stented prosthetic heart valve. The delivery device includes a delivery sheath slidably disposed over an inner shaft, and a capture assembly. The capture assembly includes a spindle and a biasing member. The spindle is attached to the inner shaft and defines slot. The biasing member is disposed within the slot and self-transitions from a deflected condition to a normal condition. In a delivery state, the delivery sheath retains the prosthesis over the inner shaft and coupled to the spindle via the capture slot, including a portion of the prosthetic valve being engaged within the slot and the biasing member forced to the deflected condition. In a deployment state, the delivery sheath is proximally withdrawn and the biasing member self-transitions toward the normal condition to eject the prosthetic valve from the capture slot.

摘要翻译： 用于经皮递送和展开支架假体心脏瓣膜的输送系统。 输送装置包括可滑动地设置在内轴上的输送护套和捕获组件。 捕获组件包括主轴和偏置构件。 主轴连接到内轴并定义槽。 偏置构件设置在槽内并且从偏转状态自适应转换到正常状态。 在输送状态下，输送护套将假体保持在内轴上并且经由捕获槽连接到心轴，包括一部分假肢瓣接合在狭槽内，并且偏置构件被迫到偏转状态。 在展开状态下，输送护套被近端拉出，并且偏压构件自动转向正常状态，以从捕获槽排出假体瓣膜。

公开(公告)号：US20090287290A1

公开(公告)日：2009-11-19

申请号：US12358084

申请日：2009-01-22

申请人： Patrick E. Macaulay ,  Robert J. Murray ,  Trevor Greenan ,  Timothy R. Ryan ,  Charles Tabor ,  Matthew J. Birdsall ,  Gianfranco Pellegrini

发明人： Patrick E. Macaulay ,  Robert J. Murray ,  Trevor Greenan ,  Timothy R. Ryan ,  Charles Tabor ,  Matthew J. Birdsall ,  Gianfranco Pellegrini

IPC分类号： A61F2/06

CPC分类号： A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9534 ,  A61F2002/9665 ,  A61F2250/0098

摘要： A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end, a distal end, and a base portion with a plurality of extending elements, wherein each of the extending elements is engageable with a portion of a stent of a prosthetic heart valve. The delivery system further includes a sleeve having an inner area. The sheath is longitudinally moveable relative to the base portion from a first position where the inner area of the sleeve at least partially covers the extending elements of the base portion to a second position where the extending elements are not positioned within the inner area of the sleeve.

摘要翻译： 一种用于将支架假体心脏瓣膜递送到患者的内腔的输送系统，所述输送系统包括具有近端，远端和具有多个延伸元件的基部的管状体，其中每个所述延伸元件 可与假体心脏瓣膜的支架的一部分接合。 输送系统还包括具有内部区域的套筒。 护套从第一位置可相对于基部纵向移动，其中套筒的内部区域至少部分地将基部的延伸元件覆盖到第二位置，在第二位置，延伸元件不位于套筒的内部区域内 。

公开(公告)号：US06496038B1

公开(公告)日：2002-12-17

申请号：US09608857

申请日：2000-06-30

申请人： Milo D. Sprague ,  Rajesh Kumar ,  Robert J. Murray

发明人： Milo D. Sprague ,  Rajesh Kumar ,  Robert J. Murray

IPC分类号： H03K19096

CPC分类号： H03K19/0963 ,  H03K5/1534

摘要： A pulsed circuit topology including a pulsed domino flip-flop. A circuit includes a domino logic gate having a domino output node responsive to input data during an evaluate pulse. Reset circuitry initiates and self-terminates a reset pulse during which the domino output node is precharged. A latch responsive to a first pulsed clock input signal is provided to latch data indicated at the domino output node.

摘要翻译： 包括脉冲多米诺触发器的脉冲电路拓扑。 电路包括具有在评估脉冲期间响应于输入数据的多米诺骨牌输出节点的多米诺骨牌逻辑门。 复位电路启动并自动终止多米诺骨牌输出节点预充电的复位脉冲。 提供响应于第一脉冲时钟输入信号的锁存器来锁存在多米诺骨牌输出节点处指示的数据。

公开(公告)号：US5691408A

公开(公告)日：1997-11-25

申请号：US612383

申请日：1996-03-07

申请人： Robert J. Murray

发明人： Robert J. Murray

IPC分类号： C09J121/02 ,  C08K3/00

CPC分类号： C09J121/02

摘要： A process for manufacturing a water based adhesive which is substantially free of organic solvents and is useful as an adhesive for bonding natural rubber compounds, synthetic rubber compounds and a combination of natural and synthetic rubber compounds, especially during the formation of a tire.

摘要翻译： 一种水性粘合剂的制造方法，其基本上不含有机溶剂，并且可用作粘合天然橡胶化合物，合成橡胶化合物以及天然和合成橡胶化合物的组合的粘合剂，特别是在轮胎形成期间。

公开(公告)号：US5455259A

公开(公告)日：1995-10-03

申请号：US221076

申请日：1994-03-31

申请人： Ronald C. Griffith ,  Robert J. Murray ,  Michael Balestra ,  Donald Mathisen

发明人： Ronald C. Griffith ,  Robert J. Murray ,  Michael Balestra ,  Donald Mathisen

IPC分类号： A61K31/135 ,  A61K31/16 ,  A61K31/165 ,  A61K31/245 ,  A61K31/275 ,  A61K31/44 ,  C07C211/27 ,  C07C211/29 ,  C07C215/52 ,  C07C217/60 ,  C07C237/00 ,  C07C237/06 ,  C07C237/08 ,  C07C237/10 ,  C07C255/58 ,  C07C271/12 ,  C07D213/38 ,  C07K5/06 ,  C07D213/36

CPC分类号： A61K31/16 ,  A61K31/135 ,  A61K31/165 ,  A61K31/245 ,  A61K31/275 ,  A61K31/44 ,  C07C211/27 ,  C07C211/29 ,  C07C215/52 ,  C07C217/60 ,  C07C237/00 ,  C07C237/06 ,  C07C237/08 ,  C07C237/10 ,  C07C255/58 ,  C07C271/12 ,  C07D213/38 ,  C07K5/06

摘要： (S)-.alpha.-phenyl-2-pyridineethanamine, and its pharmaceutically acceptable derivatives, are useful in the treatment of neurodegenerative disorders, and exhibit linear pharmacokinetics.

摘要翻译： （S）-α-苯基-2-吡啶乙胺及其药学上可接受的衍生物可用于治疗神经变性疾病，并呈现线性药代动力学。

公开(公告)号：US4537966A

公开(公告)日：1985-08-27

申请号：US564540

申请日：1983-12-22

申请人： Robert J. Murray

发明人： Robert J. Murray

IPC分类号： C07D231/56 ,  C07D471/04

CPC分类号： C07D231/56 ,  C07D471/04

摘要： Aminobenzoyl-1H-indazol-3-ols which are useful as immunomodulators and in controlling inflammation in warm-blooded animals are prepared.

摘要翻译： 制备用作免疫调节剂并控制温血动物炎症的氨基苯甲酰基-1H-吲唑-3-醇。

公开(公告)号：US4409571A

公开(公告)日：1983-10-11

申请号：US303806

申请日：1981-09-21

申请人： Robert F. Milsom ,  Robert J. Murray ,  Ian Flinn

发明人： Robert F. Milsom ,  Robert J. Murray ,  Ian Flinn

IPC分类号： H03H9/25 ,  H03H3/08 ,  H03H9/02 ,  H03H9/64 ,  H03H9/145

CPC分类号： H03H9/6489 ,  H03H9/02559 ,  H03H9/02866

摘要： Surface acoustic wave bandpass transversal filters, e.g. television intermediate frequency filters, comprising a +.theta..degree. rotated Y-cut X-propagating lithium niobate substrate with .theta. in the range from 121.degree. to 127.degree., preferably 123.degree. to 125.degree.. For a suitable range of filter bandwidths (35 db bandwidth between 0.05 and 0.5) these substrates provide reduced degradation of the filter upper stopband predominantly due to indirect bulk shear waves in the frequency range from the passband up to the frequency where direct bulk longitudinal wave degradation becomes significant. This frequency range is 41.5 MHz to approximately 55 MHz for a U.K. system t.v. i.f. filter and is 60.25 MHz to approximately 90 MHz for a Japanese system t.v. i.f. filter.

摘要翻译： 表面声波带通横向滤波器，例如 电视中频滤波器，包括θ-θ旋转的Y切X扩散铌酸锂基片，θ在121°至127°之间，优选123°至125°。 对于适当范围的滤波器带宽（35db带宽在0.05和0.5之间），这些衬底提供了过滤器上阻挡带的降低的降低，主要是由于从通带到直接体积纵波衰减的频率范围内的间接体积剪切波 变得重要 对于英制系统t.v，该频率范围为41.5MHz至约55MHz。 如果。 对于日本系统t.v，滤波器为60.25MHz至约90MHz。 如果。 过滤。

公开(公告)号：US4369914A

公开(公告)日：1983-01-25

申请号：US270594

申请日：1981-06-04

申请人： Joseph Langston, Jr. ,  Robert J. Murray

发明人： Joseph Langston, Jr. ,  Robert J. Murray

IPC分类号： B65D5/66 ,  B65D5/64 ,  B65D5/56

CPC分类号： B65D5/6626 ,  Y10S229/909

摘要： A box with a hinged lid is formed from a single sheet of cut and scored paperboard, the box being in the form of a tray having front, back and end walls and a lid which are reinforced by multiple plies of material so as to increase their rigidity, with a substantial thickness at the top edge of the front wall on which the lid is adapted to rest when closed, and with certain of the walls being reinforced by inserts, and the hinge structure joining the back wall and the multi-ply lid being such that the lid tends to close but may be readily held in an open position so as to permit access to the body of the box which is filled with a product such as cigars or similar products.

摘要翻译： 具有铰接盖的盒子由单张切割和刻划的纸板形成，该盒子是具有前，后和端壁的托盘的形式，以及由多层材料增强的盖子，从而增加它们 刚性，在前壁的顶部边缘处具有相当大的厚度，盖子在关闭时适于保持，并且一些壁由插入件加强，并且铰链结构连接后壁和多层盖子 使得盖倾向于闭合，但可以容易地保持在打开位置，以便允许进入填充有诸如雪茄或类似产品的产品的箱体。

公开(公告)号：US08623075B2

公开(公告)日：2014-01-07

申请号：US13091917

申请日：2011-04-21

申请人： Robert J. Murray, III ,  Charles Tabor ,  Andrew Crisman ,  Adam Shipley

发明人： Robert J. Murray, III ,  Charles Tabor ,  Andrew Crisman ,  Adam Shipley

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2230/0054

摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve.

摘要翻译： 一种与具有附接有阀结构的支架框架的假体心脏瓣膜一起使用的输送系统包括：轴组件，包括远端，中间部分和设置在远端附近的第一联接结构， 经由第一系绳的假体心脏瓣膜的远端。 护套组件限定尺寸为可滑动地容纳轴组件的内腔。 输送系统构造成从护套组件包围假体心脏瓣膜的负载状态转换到其中护套组件从假体心脏瓣膜抽出的展开状态。 第一联接结构构造成在第一方向上被操纵以提供假体心脏瓣膜的远端的可控膨胀或收缩。

公开(公告)号：US6000016A

公开(公告)日：1999-12-07

申请号：US850686

申请日：1997-05-02

申请人： Steve Curtis ,  Robert J. Murray ,  Helen Opie

发明人： Steve Curtis ,  Robert J. Murray ,  Helen Opie

IPC分类号： G06F1/32 ,  G06F9/30 ,  G06F9/308 ,  G06F9/355 ,  G06F9/38 ,  G06F12/08 ,  G06F12/00

CPC分类号： G06F9/3826 ,  G06F1/3203 ,  G06F1/3287 ,  G06F12/0875 ,  G06F9/30018 ,  G06F9/30105 ,  G06F9/3013 ,  G06F9/30141 ,  G06F9/30145 ,  G06F9/30167 ,  G06F9/355 ,  G06F9/3832 ,  G06F9/3877 ,  G06F9/3879 ,  Y02B60/1282

摘要： A microprocessor includes a register file that contains registers for storing pieces of data for use by execution units that receive the pieces of data through source ports. A bypass cache includes data registers into which pieces of data from the execution units are written. Data can be written to and read from the bypass cache in fewer clocks cycles than it can be written to and read from the register file. A content addressable memory array (CAM) includes address registers into which destination addresses are written which correspond to the pieces of data in the data registers. In the case of a particular piece of data, the particular data register into which the piece of data is written and the particular address register into which the corresponding destination address is written is controlled by the position of a write pointer provided by a rotating write pointer unit. The CAM includes a comparators that compare the destination address with a source address. If there is a match, a read port is enabled which provides the piece of data in the corresponding data register to conductors leading to the source port. Multiplexers select between pieces of data in the register file and a pieces of data in the data registers of the bypass cache.

摘要翻译： 微处理器包括一个寄存器文件，该寄存器文件包含用于存储数据的寄存器，以便由通过源端口接收数据的执行单元使用。 旁路高速缓存包括写入来自执行单元的数据的数据寄存器。 数据可以以更少的时钟周期写入和从旁路缓存读取，而不是从寄存器文件写入和读取数据。 内容可寻址存储器阵列（CAM）包括写入与数据寄存器中的数据片对应的目的地地址的地址寄存器。 在特定数据段的情况下，写入数据的特定数据寄存器和写入对应目标地址的特定地址寄存器由旋转写指针提供的写指针的位置来控制 单元。 CAM包括将目的地址与源地址进行比较的比较器。 如果存在匹配，则读端口被使能，其将对应数据寄存器中的数据提供给通向源端口的导体。 多路复用器选择寄存器文件中的数据段和旁路缓存的数据寄存器中的数据。