公开(公告)号：US07008440B2

公开(公告)日：2006-03-07

申请号：US10256493

申请日：2002-09-26

申请人： Eduardo Chi Sing ,  Mark Ashby ,  Luis Urquidi

发明人： Eduardo Chi Sing ,  Mark Ashby ,  Luis Urquidi

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B17/3498 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2017/00898 ,  A61B2090/062

摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an producer sheath which is already in place within a tissue tract. The system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.

摘要翻译： 用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。 该系统允许止血促进材料通过已经在组织道内就位的生产者护套递送。 该系统包括可控制的尖端，其可插入穿过引导器鞘以定位和闭塞血管穿刺部位，以及用于接收并输送止血促进材料到血管穿刺部位的水合室。 系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

公开(公告)号：US06984219B2

公开(公告)日：2006-01-10

申请号：US09859682

申请日：2001-05-18

申请人： Mark Ashby ,  Andrew Cragg ,  Luis Urquidi ,  Eduardo Chi-Sing ,  Eric Lee

发明人： Mark Ashby ,  Andrew Cragg ,  Luis Urquidi ,  Eduardo Chi-Sing ,  Eric Lee

IPC分类号： A61F13/36

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2090/062

摘要： A depth and puncture control system for a blood vessel hemostasis system includes a blood vessel puncture control tip which, when positioned in the lumen of a blood vessel, can inhibit the flow of blood out of the puncture site. When used together with a pledget delivery cannula and a pledget pusher, the control tip and the delivery catheter can both inhibit blood loss out the puncture site and inhibit the introduction of pledget material and tissue fragments into the blood vessel. The system also includes a handle which releasably connects together the control tip, pusher, and delivery cannula to permit limited longitudinal motion between the control tip and the delivery cannula, and between the pusher and the delivery cannula.

公开(公告)号：US06863680B2

公开(公告)日：2005-03-08

申请号：US10007204

申请日：2001-11-08

申请人： Mark Ashby

发明人： Mark Ashby

IPC分类号： A61B17/00 ,  A61B19/00 ,  A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2090/062

摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an introducer sheath which is already in place within a tissue tract. This system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.

摘要翻译： 用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。 该系统允许止血促进材料通过已经在组织管内已经就位的导引器鞘被递送。 该系统包括可控制的尖端，其可插入穿过引导器护套以定位和闭塞血管穿刺部位，以及用于接收和输送止血促进材料到血管穿刺部位的水合室。 系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

公开(公告)号：US20050033360A1

公开(公告)日：2005-02-10

申请号：US10857471

申请日：2004-05-28

申请人： Eduardo Sing ,  Luis Urquidi ,  Mark Ashby ,  Andrew Cragg ,  Tom Furey ,  Robert Bowes ,  Vincent Tangherlini

发明人： Eduardo Sing ,  Luis Urquidi ,  Mark Ashby ,  Andrew Cragg ,  Tom Furey ,  Robert Bowes ,  Vincent Tangherlini

IPC分类号： A61B17/00 ,  A61B17/10

CPC分类号： A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00672

摘要： A system and method for delivering a pledget of hemostasis promoting material to a blood vessel puncture to facilitate hemostasis, having an introducer sheath having an inner diameter and an outer diameter, a control tip coupled to the introducer sheath, and a self-expandable member disposed around a portion of the control tip to control blood flow at the blood vessel puncture.

摘要翻译： 一种用于将止血促进材料输送到血管穿刺以促进止血的系统和方法，具有引导器护套，其具有内径和外径，连接到导引鞘的控制尖端和设置在其上的自扩张构件 围绕控制尖端的一部分，以控制血管穿刺处的血流。

公开(公告)号：US06846320B2

公开(公告)日：2005-01-25

申请号：US09960389

申请日：2001-09-24

申请人： Mark Ashby ,  Vaughn P. Whalen ,  Eduardo Chi Sing

发明人： Mark Ashby ,  Vaughn P. Whalen ,  Eduardo Chi Sing

IPC分类号： A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B17/03 ,  A61B17/04 ,  A61B17/08 ,  A61B19/00 ,  A61F2/00 ,  A61M27/00

CPC分类号： A61B17/0057 ,  A61B10/02 ,  A61B10/0233 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654

摘要： A biopsy cannula and a delivery catheter are configured to deliver one or more absorbable sponge pledgets to a biopsy site after removal of one or more tissue samples from the site. The delivery catheter allows a large amount of hydrated sponge material to be delivery to the biopsy site to facilitate hemostasis. One example of the delivery catheter includes a closed distal end, a side port, a tapered section, and an enlarged proximal portion for receiving the pledget. The side port of the delivery catheter is arranged to delivery the pledget through the side port of the biopsy cannula. In order to fill a relatively large biopsy site where multiple tissue samples have been taken in a radial pattern, the biopsy cannula is rotated and additional pledgets are delivered to the biopsy site at different radial locations. The absorbable sponge pledget may also be used as a marker for location of the biopsy site at a later time.

摘要翻译： 活检插管和递送导管构造成在从该部位移除一个或多个组织样本之后将一个或多个可吸收海绵质量递送到活检部位。 输送导管允许大量水合海绵材料输送到活检部位以促进止血。 输送导管的一个实例包括封闭的远端，侧端口，锥形部分和用于接收毛细管的扩大的近端部分。 输送导管的侧端口布置成通过活检插管的侧端口递送毛细管。 为了填充已经以径向图案拍摄多个组织样本的相对较大的活检部位，旋转活检插管并且在不同的径向位置将额外的药物递送至活组织检查部位。 吸收性海绵片也可以用作活检部位的位置的标记。

公开(公告)号：US06610026B2

公开(公告)日：2003-08-26

申请号：US09810931

申请日：2001-03-16

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61B1704

CPC分类号： A61M37/0069 ,  A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2013/00463 ,  A61M31/00 ,  A61M37/00

摘要： A method of hydrating a sponge material for delivery to a body. The method includes the steps of placing a dry piece of sponge in a container at a first pressure. A hydrating fluid is then introduced into the container to hydrate the sponge. The pressure within the container is changed between the first pressure and a second pressure. At least a portion of the hydrating fluid is removed from the sponge, and the sponge is delivered to a bodily site.

摘要翻译： 将海绵材料保湿以递送到身体的方法。 该方法包括以干燥的海绵放置在第一压力的容器中的步骤。 然后将水合流体引入容器中以使海绵水合。 容器内的压力在第一压力和第二压力之间变化。 从海绵中去除至少一部分水合流体，将海绵输送到身体部位。

公开(公告)号：US06440153B2

公开(公告)日：2002-08-27

申请号：US09953395

申请日：2001-09-14

申请人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

发明人： Andrew H. Cragg ,  Rodney Brenneman ,  Mark Ashby

IPC分类号： A61B1708

CPC分类号： A61B17/0057 ,  A61B10/0233 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654

摘要： A system including an adaptor and a syringe is used for facilitating hemostasis of a biopsy tract or other puncture wound by delivery of an absorbable sponge in a hydrated state into the wound. The adaptor includes a tapered lumen for hydrating and compressing the relatively large absorbable sponge for delivery through a relatively small cannula, such as a biopsy needle. The hydrated absorbable sponge is injected through the biopsy needle into the biopsy tract by fluid. Alternatively, the sponge may be delivered to the biopsy needle by injection of fluid and then delivered to the biopsy tract by a plunger or stylet. The implanted absorbable sponge facilitates hemostasis at the biopsy site or other puncture wound and minimizes the chance of internal bleeding. The absorbable sponge material is absorbed by the body over time.

摘要翻译： 包括适配器和注射器的系统用于促进通过将水合状态的可吸收海绵递送到伤口中来伤口活检管或其他穿刺的止血。 适配器包括锥形内腔，用于水合和压缩相对较大的可吸收海绵，以通过相对小的插管（例如活检针）递送。 将水合吸收海绵通过活检针注射入活检管内。 或者，可以通过注射流体将海绵递送到活检针，然后通过柱塞或通管针递送到活检管道。 植入的可吸收海绵有助于活检部位或其他穿刺伤口止血，并最大限度地减少内部出血的机会。 可吸收的海绵材料随着时间的过去被身体吸收。

公开(公告)号：US09629740B2

公开(公告)日：2017-04-25

申请号：US13639483

申请日：2011-04-06

申请人： Outhit Bouasaysy ,  Mark Ashby

发明人： Outhit Bouasaysy ,  Mark Ashby

IPC分类号： A61F5/00 ,  A61L2/23

CPC分类号： A61F5/0033 ,  A61F5/003 ,  A61F5/0036 ,  A61F5/0043 ,  A61F5/0089 ,  A61L2/23 ,  A61M25/10182

摘要： Inflation devices for inflating intragastric devices and associated systems and methods are disclosed herein. In several embodiments, an inflation device can include a tube, an inner detent, and an outer detent. The tube can extend from a proximal portion of the inflation device to a distal portion of the inflation device, and can include a handle at the proximal portion and a barb at the distal portion. The barb can have a cross-sectional dimension greater than a cross-sectional dimension of a corresponding inflation port of an intragastric device. The inner detent can be positioned over the barb and can include a mating interface. The outer detent can be positioned over the inner detent, and can be configured to attach over a proximal cap of the intragastric device. The tube can be longitudinally advanceable relative to at least one of the inner and outer detents.

公开(公告)号：US20130261654A1

公开(公告)日：2013-10-03

申请号：US13877644

申请日：2011-10-07

申请人： Outhit Bouasaysy ,  Mark Ashby

发明人： Outhit Bouasaysy ,  Mark Ashby

IPC分类号： A61F5/00 ,  A61M25/10

CPC分类号： A61F5/003 ,  A61F5/0036 ,  A61J15/0042 ,  A61J15/0049 ,  A61L31/041 ,  A61L2430/22 ,  A61M25/1029 ,  C08L83/04

摘要： An inflatable balloon of an intragastric device comprises a substantially homogonous lend of polydiphenylsiloxane and polydimethylsiloxane. The substantially homogenous blend improves elongation percentage, tear strength, permeability, and modulus as compared to its constituent parts taken alone.

摘要翻译： 胃内装置的可膨胀气囊包括聚二苯基硅氧烷和聚二甲基硅氧烷的基本均匀的借装。 与其单独使用的组分相比，基本均匀的共混物提高了伸长率，撕裂强度，渗透性和模量。

公开(公告)号：US07621936B2

公开(公告)日：2009-11-24

申请号：US10754824

申请日：2004-01-09

申请人： Andrew H. Cragg ,  Mark Ashby

发明人： Andrew H. Cragg ,  Mark Ashby

IPC分类号： A61B17/03

CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2090/062

摘要： A method of facilitating hemostasis of a blood vessel puncture. The method includes the steps of inserting a tubular device into a puncture in a blood vessel to establish access to the blood vessel, providing a vessel closure system around the tubular device, introducing a hemostatic material into a space between the tubular device and vessel closure system, and delivering the hemostatic material adjacent to the puncture to facilitate hemostasis of the puncture.