公开(公告)号：US20230257728A1

公开(公告)日：2023-08-17

申请号：US18166707

申请日：2023-02-09

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Lydia Dankmeyer ,  David A. Estell ,  Frits Goedegebuur ,  Thijs Kaper ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US11499146B2

公开(公告)日：2022-11-15

申请号：US15736401

申请日：2016-06-17

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Richard R. Bott ,  David A. Estell ,  Harm Mulder ,  Frits Goedegebuur ,  Jian Yao ,  Sina Pricelius ,  Miles Scotcher

IPC: C12N9/54 ,  C11D3/386

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more Bacillus gibsonii-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20200172837A1

公开(公告)日：2020-06-04

申请号：US16532560

申请日：2019-08-06

Applicant: DANISCO US INC

Inventor： Marc Kolkman ,  Frits Goedegebuur ,  Harm Mulder ,  Lilia Maria Babe

IPC: C11D3/386 ,  A23K20/189 ,  C11D3/00 ,  A23K50/40 ,  C11D11/00 ,  C12N9/54

Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.

公开(公告)号：US20190309278A1

公开(公告)日：2019-10-10

申请号：US16309267

申请日：2017-06-18

Applicant: DANISCO US INC

Inventor： Richard R. Bott ,  David A. Estell ,  Frits Goedegebuur ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/54 ,  C11D3/386

Abstract: Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20180216090A1

公开(公告)日：2018-08-02

申请号：US15557158

申请日：2016-03-14

Applicant: Danisco US Inc.

Inventor： Harm Mulder ,  Jeffrey Veach Miller ,  Frits Goedegebuur ,  David A. Estell ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R. Bott ,  Miles Christopher Scotcher ,  Jian Yao

IPC: C12N9/50 ,  C11D3/386

CPC classification number: C12N9/50 ,  C11D3/386 ,  C11D3/38663 ,  C11D3/38681 ,  C12N9/54 ,  C12Y304/21062

Abstract: The present disclosure provides LG12-clade enzyme variants, compositions comprising these enzyme variants, and method of using these enzymes and compositions, as well as the polynucleotides encoding these enzymes, the vectors comprising these polynucleotides, and the host cells transformed with such vectors.

公开(公告)号：US11946081B2

公开(公告)日：2024-04-02

申请号：US16471686

申请日：2017-12-19

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Lydia Dankmeyer ,  Frits Goedegebuur ,  Thijs Kaper ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/38681 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant. nucleic acid encoding same. and compositions and methods related to the production and use thereof. including one or more Bacillus gibsonii-clade subtilisin variant that has improved soil removal compared to one or more reference subtilisin.

公开(公告)号：US11946080B2

公开(公告)日：2024-04-02

申请号：US16309267

申请日：2017-06-18

Applicant: DANISCO US INC

Inventor： Richard R. Bott ,  David A. Estell ,  Frits Goedegebuur ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/50 ,  C11D3/386 ,  C12N9/54 ,  C12N15/52

CPC classification number: C12N9/54 ,  C11D3/386 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US11898177B2

公开(公告)日：2024-02-13

申请号：US17373307

申请日：2021-07-12

Applicant: DANISCO US INC.

Inventor： Luis G Cascao-Pereira ,  David A Estell ,  Marc Anton Bernhard Kolkman ,  Harm Mulder

IPC: C12N9/28 ,  A21D8/04 ,  C11D3/386 ,  D06L1/14 ,  D06L4/40

CPC classification number: C12N9/2417 ,  A21D8/042 ,  C11D3/386 ,  C12Y302/01001 ,  D06L1/14 ,  D06L4/40

Abstract: Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.

公开(公告)号：US10731144B2

公开(公告)日：2020-08-04

申请号：US15575959

申请日：2016-06-17

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Carol Marie Fioresi ,  Frits Goedegebuur ,  Harm Mulder

IPC: C12N9/54 ,  C12N15/52

Abstract: The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. Bacillus sp. host cells). The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.

公开(公告)号：US20180237761A1

公开(公告)日：2018-08-23

申请号：US15736401

申请日：2016-06-17

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Richard R. Bott ,  David A. Estell ,  Harm Mulder ,  Frits Goedegebuur ,  Jian Yao ,  Sina Pricelius ,  Miles Scotcher

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38663 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more Bacillus gibsonii-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.