公开(公告)号：US11473075B2

公开(公告)日：2022-10-18

申请号：US16720106

申请日：2019-12-19

Applicant: DANISCO US INC

Inventor： David A. Estell ,  Frits Goedegebuur ,  Marc Anton Bernhard Kolkman ,  Rie Mejldal ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R Bott ,  Jian Yao ,  Roopa Santosh Ghirnikar

IPC: C12N9/54 ,  C11D3/386

Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

公开(公告)号：US11053488B2

公开(公告)日：2021-07-06

申请号：US16469464

申请日：2017-12-14

Applicant: DANISCO US INC.

Inventor： Richard Bott ,  David A. Estell ,  Neeraj Pandey ,  Sina Pricelius ,  Jian Yao

IPC: C12N9/42 ,  C11D3/386 ,  D21H17/00

Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.

公开(公告)号：US20190264187A1

公开(公告)日：2019-08-29

申请号：US16404828

申请日：2019-05-07

Applicant: DANISCO US INC

Inventor： Lilia M Babe ,  Roopa Santosh Ghirnikar ,  Frits Goedegebuur ,  Xiaogang Gu ,  Marc Anton Bernhard Kolkman ,  Jian Yao ,  Shukun Yu

IPC: C12N9/52 ,  A23K10/14 ,  C11D3/386 ,  A23K20/189

Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.

公开(公告)号：US20180112204A1

公开(公告)日：2018-04-26

申请号：US15572882

申请日：2016-05-13

Applicant: DANISCO US INC.

Inventor： David A. Estell ,  Frits Goedegebuur ,  Marc Kolkman ,  Rie Mejldal ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R. Bott ,  Jian Yao ,  Roopa Ghirnikar

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38681 ,  C12Y304/21062

Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

公开(公告)号：US12180522B2

公开(公告)日：2024-12-31

申请号：US17328003

申请日：2021-05-24

Applicant: DANISCO US INC

Inventor： Richard Bott ,  David A. Estell ,  Neeraj Pandey ,  Sina Pricelius ,  Jian Yao

IPC: C12N9/24 ,  C11D3/386 ,  C12N9/42 ,  D21H17/00

Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.

公开(公告)号：US20240191220A1

公开(公告)日：2024-06-13

申请号：US18482990

申请日：2023-10-09

Applicant: Danisco US Inc.

Inventor： Viktor Yuryevich Alekseyev ,  Neelam S. Amin ,  Luis G. Cascao-Pereira ,  Katherine D. Collier ,  David A. Estell ,  James T. Kellis, JR. ,  Ayrookaran J. Poulose ,  Philiip F. Souter ,  Glenn S. Ward ,  Katherine Augustyn ,  Jian Yao

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38681

Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

公开(公告)号：US11447762B2

公开(公告)日：2022-09-20

申请号：US16030994

申请日：2018-07-10

Applicant: DANISCO US INC

Inventor： Viktor Yuryevich Alekseyev ,  Neelam S. Amin ,  Luis G. Cascao-Pereira ,  Katherine D. Collier ,  David A. Estell ,  James T. Kellis, Jr. ,  Ayrookaran J. Poulose ,  Philip F. Souter ,  Glenn S. Ward ,  Katherine Augustyn ,  Jian Yao

IPC: C12N9/54 ,  C11D3/386

Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

公开(公告)号：US10696958B2

公开(公告)日：2020-06-30

申请号：US15835551

申请日：2017-12-08

Applicant: DANISCO US INC.

Inventor： Lilia M. Babe ,  Frits Goedegebuur ,  Roopa Ghirnikar ,  Xiaogang Gu ,  Marc Kolkman ,  Jian Yao

IPC: C12N9/52 ,  C12N9/48 ,  C12N9/54 ,  C11D3/386

Abstract: Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.

公开(公告)号：US20160108388A1

公开(公告)日：2016-04-21

申请号：US14893837

申请日：2014-05-29

Applicant: DANISCO US INC.

Inventor： Lilia M. Babe ,  Roopa Ghirnikar ,  Frits Goedegebuur ,  Xiaogang Gu ,  Marc Kolkman ,  Jian Yao ,  Shukun Yu

IPC: C12N9/54 ,  C11D3/39 ,  C11D3/386

CPC classification number: C12N9/54 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C11D3/38681 ,  C11D3/3945 ,  C12Y304/24 ,  D06L4/40 ,  D06P5/137

Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.

Abstract translation: 本发明组合物和方法的方面涉及编码新型金属蛋白酶的新型金属蛋白酶多核苷酸，其组合物及其使用方法。

公开(公告)号：US08658406B2

公开(公告)日：2014-02-25

申请号：US13920043

申请日：2013-06-17

Applicant: Danisco US Inc.

Inventor： Nigel Dunn-Coleman ,  Frits Goedegebuur ,  Michael Ward ,  Jian Yao

IPC: C12P7/06 ,  C12Q1/68 ,  C12Q1/34 ,  C12N9/42 ,  C12N15/00 ,  C12N1/20 ,  C12P21/04 ,  C12P21/06 ,  C07H21/04 ,  C12N1/00

CPC classification number: C12N9/2437 ,  C11D3/38 ,  C11D3/38636 ,  C11D3/38645 ,  C12N9/2445 ,  C12N15/1137 ,  C12N2310/11 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.

Abstract translation: 本发明提供了一种命名为egl7的新型内切葡聚糖酶核酸序列和相应的EGVII氨基酸序列。 本发明还提供了包含编码EGVII的核酸序列，重组EGVII蛋白的表达载体和宿主细胞及其制备方法。