公开(公告)号：US11473075B2

公开(公告)日：2022-10-18

申请号：US16720106

申请日：2019-12-19

Applicant: DANISCO US INC

Inventor： David A. Estell ,  Frits Goedegebuur ,  Marc Anton Bernhard Kolkman ,  Rie Mejldal ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R Bott ,  Jian Yao ,  Roopa Santosh Ghirnikar

IPC: C12N9/54 ,  C11D3/386

Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

公开(公告)号：US20180112204A1

公开(公告)日：2018-04-26

申请号：US15572882

申请日：2016-05-13

Applicant: DANISCO US INC.

Inventor： David A. Estell ,  Frits Goedegebuur ,  Marc Kolkman ,  Rie Mejldal ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R. Bott ,  Jian Yao ,  Roopa Ghirnikar

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38681 ,  C12Y304/21062

Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

公开(公告)号：US11661567B2

公开(公告)日：2023-05-30

申请号：US16305259

申请日：2017-05-31

Applicant: DANISCO US INC.

Inventor： David Marquez ,  Michael Stoner ,  James T. Kellis, Jr. ,  Adam Garske ,  Joshua Roy Basler ,  Katherine Augustyn ,  Priyanka Chandrasekaran ,  Miles Christopher Scotcher ,  Lilia Maria Babe ,  Richard R. Bott ,  David A. Estell ,  Gudrun Vogtentanz ,  Sina Pricelius ,  Jian Yao

IPC: C11D3/386 ,  C12N9/54 ,  C12N15/52

CPC classification number: C11D3/386 ,  C12N9/54 ,  C12N15/52 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20160222368A1

公开(公告)日：2016-08-04

申请号：US15021681

申请日：2014-09-11

Applicant: DANISCO US INC.

Inventor： Lilia M. Babe ,  David A. Estell ,  Frits Goedegebuur ,  Richard R. Bott ,  Marc Kolkman ,  Harm Mulder ,  Brian F. Schmidt ,  Katherine Augustyn ,  Munroop Atwal ,  Abby Marquez

IPC: C12N9/54 ,  C12N5/071 ,  A23K20/189 ,  D06M16/00 ,  C14C1/06 ,  D21C9/10 ,  C11D3/386

CPC classification number: C12N9/54 ,  A23K20/189 ,  C11D3/386 ,  C11D3/38681 ,  C12N5/0602 ,  C12Y304/21062 ,  C14C1/065 ,  D06M16/003 ,  D21C9/1063

Abstract: The present invention provides serine protease enzymes produced from LG12-clade enzymes. In addition, the present invention provides compositions comprising these protease enzymes. In some embodiments, the present invention provides cleaning compositions comprising at least one of these protease enzymes.

Abstract translation: 本发明提供了由LG12-分支酶产生的丝氨酸蛋白酶。 此外，本发明提供包含这些蛋白酶的组合物。 在一些实施方案中，本发明提供了包含这些蛋白酶中的至少一种的清洁组合物。

公开(公告)号：US20240191220A1

公开(公告)日：2024-06-13

申请号：US18482990

申请日：2023-10-09

Applicant: Danisco US Inc.

Inventor： Viktor Yuryevich Alekseyev ,  Neelam S. Amin ,  Luis G. Cascao-Pereira ,  Katherine D. Collier ,  David A. Estell ,  James T. Kellis, JR. ,  Ayrookaran J. Poulose ,  Philiip F. Souter ,  Glenn S. Ward ,  Katherine Augustyn ,  Jian Yao

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38681

Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

公开(公告)号：US11447762B2

公开(公告)日：2022-09-20

申请号：US16030994

申请日：2018-07-10

Applicant: DANISCO US INC

Inventor： Viktor Yuryevich Alekseyev ,  Neelam S. Amin ,  Luis G. Cascao-Pereira ,  Katherine D. Collier ,  David A. Estell ,  James T. Kellis, Jr. ,  Ayrookaran J. Poulose ,  Philip F. Souter ,  Glenn S. Ward ,  Katherine Augustyn ,  Jian Yao

IPC: C12N9/54 ,  C11D3/386

Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

公开(公告)号：US20210087546A1

公开(公告)日：2021-03-25

申请号：US17115329

申请日：2020-12-08

Applicant: DANISCO US INC

Inventor： NEELAM S AMIN ,  Katherine Augustyn ,  Priyanka Chandrasekaran ,  Edwn W. Lee

IPC: C12N9/54 ,  C11D3/386

Abstract: Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning, as well as in a variety of industrial applications. One embodiment is directed to one or more subtilisin variant, including one or more Bacillus sp. subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.

公开(公告)号：US20250092336A1

公开(公告)日：2025-03-20

申请号：US18914556

申请日：2024-10-14

Applicant: DANISCO US INC.

Inventor： Joshua Roy Basler ,  Michael Stoner ,  James T. Kellis, Jr. ,  Adam Garske ,  David Marquez ,  Katherine Augustyn ,  Priyanka Chandrasekaran ,  Miles Christopher Scotcher ,  Lilia Maria Babe ,  Richard R. Bott ,  David A. Estell ,  Gudrun Vogtentanz ,  Sina Pricelius ,  Jian Yao

IPC: C11D3/386 ,  C12N9/54 ,  C12N15/52

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20180216092A1

公开(公告)日：2018-08-02

申请号：US15831913

申请日：2017-12-05

Applicant: DANISCO US INC

Inventor： VIKTOR YURYEVICH ALEKSEYEV ,  Neelam S. Amin ,  Luis G. Cascao-Pereira ,  Katherine D. Collier ,  David A. Estell ,  James T. Kellis, JR. ,  Ayrookaran J. Poulose ,  Philip F. Souter ,  Glenn S. Ward ,  Katherine Augustyn ,  Jian Yao

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38681

Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

公开(公告)号：US20180216090A1

公开(公告)日：2018-08-02

申请号：US15557158

申请日：2016-03-14

Applicant: Danisco US Inc.

Inventor： Harm Mulder ,  Jeffrey Veach Miller ,  Frits Goedegebuur ,  David A. Estell ,  Katherine Augustyn ,  Lilia Maria Babe ,  Richard R. Bott ,  Miles Christopher Scotcher ,  Jian Yao

IPC: C12N9/50 ,  C11D3/386

CPC classification number: C12N9/50 ,  C11D3/386 ,  C11D3/38663 ,  C11D3/38681 ,  C12N9/54 ,  C12Y304/21062

Abstract: The present disclosure provides LG12-clade enzyme variants, compositions comprising these enzyme variants, and method of using these enzymes and compositions, as well as the polynucleotides encoding these enzymes, the vectors comprising these polynucleotides, and the host cells transformed with such vectors.