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公开(公告)号：US4876066A
公开(公告)日：1989-10-24
申请号：US73261
申请日：1987-07-14
CPC分类号： A61M1/1698 , A61M1/1625 , A61M1/1629 , A61M1/3673 , B01D63/02 , A61M1/3627 , A61M2206/16 , B01D2313/38 , B01D2313/90 , Y10S128/03
摘要： A membrane oxygenator includes an upper nested arrangement of a hard shell venous reservoir, a bowl-like defoamer within the reservoir and a heat exchanger coil vertically supported within the defoamer, and includes a membrane oxygenator unit mounted on the bottom of the upper arrangement. The oxygenator unit includes an inlet chamber with a tangential inlet providing swirling blood flow to dislodge air bubbles and centrifuge air to an upper center region of an inlet chamber where gas is exhausted through a vent. A bottom blood outlet chamber of the blood oxygenator unit has a relatively thin vertical cross-sectional area such that priming flow velocity therein discharges all air from the outlet chamber.
摘要翻译： 膜充氧器包括硬壳静脉储存器的上嵌套布置，储存器内的碗状消泡剂和垂直支撑在消泡剂内的热交换器盘管，并且包括安装在上部布置的底部的膜氧合器单元。 充氧器单元包括具有切向入口的入口室，该入口提供旋转的血流以排出气泡并将空气离心到入口室的上中心区域，在该中心区域，气体通过排气口排出。 血液充氧器单元的底部出血室具有相对薄的垂直横截面积，使得其中的起动流速从出口腔排出所有空气。
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公开(公告)号：US07837729B2
公开(公告)日：2010-11-23
申请号：US10946332
申请日：2004-09-20
申请人： Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
发明人： Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
IPC分类号： A61F2/06
CPC分类号： A61B17/3468 , A61F2/2451 , A61F2/95 , A61F2002/9511 , A61F2002/9517
摘要： The invention is a tissue shaping system, including a tissue shaping device with an expandable anchor and a lock; a delivery catheter; a delivery mechanism adapted to deliver the tissue shaping device from outside a patient to a target site within a lumen within the patient via the delivery catheter; and an actuator adapted to deliver an actuation force to the lock to lock the anchor in an expanded configuration. The invention is also a system adapted to percutaneously deliver and deploy a tissue shaping device at a target site within a lumen of a patient. The system includes: a handle; a delivery mechanism supported by the handle and adapted to deliver the tissue shaping device from outside the patient to the treatment site via a delivery catheter; and an actuator supported by the handle and adapted to deliver an actuation force to lock an anchor of the tissue shaping device in an expanded configuration.
摘要翻译： 本发明是一种组织成形系统，包括具有可扩张锚和锁的组织成形装置; 输送导管; 输送机构，其适于经由输送导管将患者外部的组织成形装置输送到患者体内的内腔内的目标部位; 以及致动器，其适于将致动力传递到所述锁以将所述锚固件锁定在扩展构型中。 本发明也是适于在患者的内腔内的目标部位经皮输送和部署组织整形装置的系统。 该系统包括：手柄; 由手柄支撑并适于经由输送导管将组织成形装置从患者外部递送到治疗部位的递送机构; 以及致动器，其由所述手柄支撑并且适于递送致动力以将所述组织整形装置的锚固件以扩展构型锁定。
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公开(公告)号：US06416526B1
公开(公告)日：2002-07-09
申请号：US09589861
申请日：2000-06-08
申请人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
发明人： Mark Wyzgala , Donald Baumgarten , Lucas S. Gordon , Eric B. Hamilton , Matt Hefner , Tom Hiblar , Edward Wulfman
IPC分类号： A61B1732
CPC分类号： A61B17/320725 , A61B17/320758 , A61B2017/00557 , A61B2017/00867 , A61B2017/320004 , A61B2017/320733
摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.
摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。
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公开(公告)号：US4493705A
公开(公告)日：1985-01-15
申请号：US406962
申请日：1982-08-10
申请人： Lucas S. Gordon , Jeanne Pierson
发明人： Lucas S. Gordon , Jeanne Pierson
CPC分类号： A61J1/10 , A61M1/3627 , A61M5/165 , A61M2205/75 , A61M5/36 , Y10S128/03
摘要： A yoke shaped collapsible blood reservoir having first and second yoke legs joined by a yoke midsection. A filter element is positioned in the yoke midsection and across the blood flow path between an inlet at the base of the first yoke leg and a blood outlet at the base of the second yoke leg. An angular blood inlet and a gradual increase in cross-sectional area from the blood inlet to the yoke midsection decreases turbulence and assists in bubble separation.
摘要翻译： 轭形可折叠血液储存器，其具有通过轭形中央部分连接的第一和第二轭腿。 过滤元件位于轭架中部，并且横跨血液流动路径，位于第一轭腿的基部处的入口与第二轭腿的底部处的血液出口之间。 血液入口角度和血液入口至椎体中央部分的横截面积逐渐增加会减少湍流并有助于气泡分离。
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公开(公告)号：US4490254A
公开(公告)日：1984-12-25
申请号：US124312
申请日：1980-02-25
CPC分类号： B01D36/001 , A61M1/3627 , B01D27/00 , B01D29/21
摘要： This invention relates to a blood filter assembly in which blood enters at the bottom end of the assembly, is directed in spirally upward path and then passes through a filter medium. After passing through the filter medium, the blood flows downwardly out of an outlet in the bottom end of the assembly. A gas vent is provided at the top end of the assembly. In its preferred embodiment, the outer shell of the assembly tapers from the bottom end to a narrower diameter top end, the filter medium is generally shaped in the form of a cylindrical tube and a core member is provided radially inwardly of said filter medium and spaced therefrom. This filter assembly is particularly useful for the removal of particulate matter, gas and other foreign materials from blood.
摘要翻译： 血液过滤器组件本发明涉及一种血液过滤器组件，其中血液进入组件的底端，被引导成螺旋上升的路径，然后通过过滤介质。 在通过过滤介质之后，血液向下流出组件底端的出口。 在组件的顶端设有排气口。 在其优选实施例中，组件的外壳从底端到较窄直径的顶端逐渐变细，过滤介质通常成形为圆柱形管的形式，并且芯构件设置在所述过滤介质的径向向内并且间隔开 由此。 该过滤器组件特别可用于从血液中除去颗粒物质，气体和其它异物。
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公开(公告)号：US08250960B2
公开(公告)日：2012-08-28
申请号：US13220444
申请日：2011-08-29
申请人： Louis R. Hayner , Evan M. Keech , Lucas S. Gordon
发明人： Louis R. Hayner , Evan M. Keech , Lucas S. Gordon
IPC分类号： B26D3/00
CPC分类号： B26D7/01 , B26D3/16 , B26D3/166 , B26D5/083 , Y10T83/02 , Y10T83/0419 , Y10T83/0596 , Y10T83/647 , Y10T83/728 , Y10T83/75 , Y10T83/7593 , Y10T83/889
摘要： Systems and methods for cutting, or trimming, a catheter at a specified location along the length of the catheter. The catheter preferably includes a stop feature which interacts with an elongate member of the cutting system to determine the catheter is in a proper position to be cut.
摘要翻译： 在沿着导管长度的特定位置切割或修整导管的系统和方法。 导管优选地包括与切割系统的细长构件相互作用以确定导管处于适当的切割位置的止动特征。
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公开(公告)号：US08182529B2
公开(公告)日：2012-05-22
申请号：US10945855
申请日：2004-09-20
申请人： Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
发明人： Lucas S. Gordon , Mark L. Mathis , Gregory Nieminen , Leonard Kowalsky , Ryan Braxtan , Brian J. Doll
CPC分类号： A61F2/95 , A61B17/3468 , A61B2017/1205 , A61F2002/9511
摘要： The invention is a method of delivering and deploying a tissue shaping device in a lumen within a patient, with the tissue shaping device including an anchor. In some embodiments the method includes the steps of: inserting a delivery catheter into the lumen; percutaneously delivering the device to a target site within the lumen through a delivery catheter; operating an actuator to expose an anchor; and operating the actuator to lock the anchor. In other, the method includes the steps of: inserting a delivery catheter into the lumen; moving the device from a cartridge into the delivery catheter; delivering the device to a target site within the lumen; operating an actuator to move the delivery catheter with respect to the anchor to expose the anchor; and expanding the anchor.
摘要翻译： 本发明是一种在组织整形装置中包括锚固件的方式，将组织成形装置递送和展开在患者体内。 在一些实施例中，该方法包括以下步骤：将输送导管插入内腔; 通过输送导管将装置经皮递送到内腔内的目标部位; 操作致动器以暴露锚; 并操作致动器以锁定锚。 另外，该方法包括以下步骤：将输送导管插入内腔; 将装置从药筒移动到输送导管中; 将装置输送到管腔内的目标部位; 操作致动器以使输送导管相对于锚固件移动以暴露锚固件; 并扩大锚点。
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公开(公告)号：US5928246A
公开(公告)日：1999-07-27
申请号：US950641
申请日：1997-10-15
申请人： Lucas S. Gordon , Hanh To
发明人： Lucas S. Gordon , Hanh To
CPC分类号： A61F2/958
摘要： A stent securing catheter including a tubular body having a longitudinal axis and defining a stent receiving lumen. The tubular body having a proximal end and a distal end wherein the distal end defines an opening into the receiving lumen. The opening into the receiving lumen is disposed at a generally acute angle to the longitudinal axis of the tubular body.
摘要翻译： 一种支架固定导管，其包括具有纵向轴线并限定支架接收内腔的管状体。 所述管体具有近端和远端，其中所述远端限定到所述接收内腔的开口。 进入接收管腔的开口以与管状体的纵向轴线成大致锐角的方式设置。
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公开(公告)号：US4902476A
公开(公告)日：1990-02-20
申请号：US56135
申请日：1987-05-29
CPC分类号： B01D63/02 , A61M1/1627 , A61M1/1629 , A61M1/1698 , A61M5/44 , A61M1/32 , A61M1/369 , A61M2205/366 , B01D2313/38 , Y10S128/03 , Y10S261/28
摘要： A heat exchanger and blood oxgenator apparatus includes a housing having a blood inlet portion, a blood outlet portion, and a housing wall defining an enclosed chamber disposed along a chamber axis between the blood input portion and the blood output portion through which to pass a quantity of blood to be temperature controlled. A heat exchanger tube having an exterior surface and a hollow interior through which to pass a heat exchange medium for purposes of exchanging heat with a quantity of blood brought into contact with the exterior surface, is disposed in a generally helical coil that is mounted within the chamber to encircle the chamber axis. A scalloped inner surface is included on the housing wall to face generally inward toward the heat exchanger tube. Spacing members disposed between the exterior surface of the heat exchanger tube and the scalloped inner surface of the housing wall retain the exterior surface spaced apart from the scalloped inner surface to define a flow passage through which to pass a quantity of blood so that the blood contacts a substantial portion of the exterior surface.
摘要翻译： 热交换器和血液氧化器装置包括具有血液入口部分，血液出口部分和壳体壁的壳体，该壳体限定了沿着血液输入部分和血液输出部分之间的腔室轴线设置的封闭腔室， 的血液要温度控制。 具有外表面和中空内部的热交换器管被设置在大致螺旋状的线圈中，所述外部表面和中空内部通过热交换介质以通过与外部表面接触的一定量的血液进行热交换。 腔室围绕腔室轴线。 扇形内表面包括在壳体壁上，以朝向热交换器管大致向内。 设置在热交换器管的外表面和壳体壁的扇形内表面之间的间隔构件保持与扇形内表面间隔开的外表面，以限定通过一定量血液的流动通道，使得血液接触 外表面的大部分。
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公开(公告)号：US4440723A
公开(公告)日：1984-04-03
申请号：US282283
申请日：1981-07-10
申请人： Lucas S. Gordon
发明人： Lucas S. Gordon
CPC分类号： A61M1/32 , A61M2206/16 , Y10S128/03
摘要： A blood oxygenator containing a means for combining oxygen-containing gas with liquid blood, the oxygenator having an outer shell portion rotatably joined to a cap portion. Preferably the cap portion includes at least one blood inlet together with an oxygen-containing gas inlet while the outer shell portion contains at least one oxygenated blood outlet and the rotatable joint between said outer shell portion and said cap portion is in venting communication with the exterior of the blood oxygenator.
摘要翻译： 含有含氧气体与液体血液混合的装置的血液充氧器，所述充氧器具有可旋转地接合到盖部分的外壳部分。 优选地，帽部分包括至少一个血液入口和含氧气体入口，而外壳部分包含至少一个含氧血液出口，并且所述外壳部分和所述帽部分之间的可旋转接合部与外部通气连通 的血液充氧器。
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