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公开(公告)号:US20090227949A1
公开(公告)日:2009-09-10
申请号:US12399548
申请日:2009-03-06
申请人: David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
发明人: David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
IPC分类号: A61M25/10
CPC分类号: A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要: Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. The balloon has one or more folds which serve as a reservoir for containing the therapeutic agent. The fold may have any of various configurations to hold the therapeutic agent. In some cases, the balloon comprises one or more lobes that forms the fold(s). The therapeutic agent may be provided in various ways. For example, the therapeutic agent may be contained in packets that rupture upon expansion of the balloon, or as a plurality of discrete bulk masses, or sealed within compartments.
摘要翻译: 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 气囊具有一个或多个折叠,其用作容纳治疗剂的储存器。 折叠可以具有保持治疗剂的各种构造中的任何一种。 在一些情况下,气囊包括形成褶皱的一个或多个凸起。 治疗剂可以以各种方式提供。 例如,治疗剂可以包含在囊膨胀时破裂的包装中,或者作为多个离散的体积块,或者密封在隔室内。
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公开(公告)号:US20120053517A1
公开(公告)日:2012-03-01
申请号:US13289490
申请日:2011-11-04
申请人: John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人: John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
IPC分类号: A61M25/10
CPC分类号: A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要: Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译: 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面,一个或多个护套设置在球囊周围,治疗剂设置在护套内,设置在护套上,被包含在护套和气囊之间的空间中,或者与护套相关联。 另一方面,气囊包括用于药物递送的微机电系统(MEMS)。
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公开(公告)号:US20090227948A1
公开(公告)日:2009-09-10
申请号:US12399386
申请日:2009-03-06
申请人: John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人: John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
CPC分类号: A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要: Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译: 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面,一个或多个护套设置在球囊周围,治疗剂设置在护套内,设置在护套上,被包含在护套和气囊之间的空间中,或者与护套相关联。 另一方面,气囊包括用于药物递送的微机电系统(MEMS)。
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公开(公告)号:US20070208276A1
公开(公告)日:2007-09-06
申请号:US11368927
申请日:2006-03-06
申请人: Angela Kornkven Volk , Karl Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
发明人: Angela Kornkven Volk , Karl Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
IPC分类号: A61M25/00
CPC分类号: A61M25/001 , A61B2017/00398 , A61B2017/00871 , A61M25/0069 , A61M25/0074 , A61M25/10 , A61M2025/0024 , A61M2025/0058 , A61M2025/0063 , A61M2025/09125
摘要: A catheter tip has an outer surface section, an inner surface section, a spatial configuration and at least one segment of electroactive polymer. The inner surface section defines a guide wire lumen. The electroactive polymer has an actuated state and a non-actuated state. In an actuated state, the electroactive polymer alters the spatial configuration of the catheter tip.
摘要翻译: 导管尖端具有外表面部分,内表面部分,空间构造和至少一个电活性聚合物部分。 内表面部分限定导丝管腔。 电活性聚合物具有致动状态和非致动状态。 在致动状态下,电活性聚合物改变导管尖端的空间构型。
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公开(公告)号:US20070078511A1
公开(公告)日:2007-04-05
申请号:US11240313
申请日:2005-09-30
申请人: Timothy Ehr , Kenneth Merdan , Jay Rassat , Derek Sutermeister
发明人: Timothy Ehr , Kenneth Merdan , Jay Rassat , Derek Sutermeister
IPC分类号: A61F2/06
CPC分类号: A61F2/856 , A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/067 , A61F2002/91508 , A61F2002/91533 , A61F2220/0091 , A61F2250/0039
摘要: A stent assembly has a first stent body and a second stent body. The first stent body defines a first lumen having a first longitudinal axis therethrough, and the second stent body defines a second lumen having a second longitudinal axis therethrough. An end of the second stent body is hingedly engaged to a portion of the first stent body, and the first lumen and the second lumen are in fluid communication with one another. The stent assembly has a undeployed and a deployed state. In the undeployed state the first longitudinal axis and the second longitudinal axis are substantially parallel to one another and the second lumen is positioned entirely within the first lumen. In the deployed state the second longitudinal axis forms an oblique angle with the first longitudinal axis.
摘要翻译: 支架组件具有第一支架主体和第二支架主体。 第一支架主体限定具有穿过其的第一纵向轴线的第一内腔,并且第二支架主体限定具有穿过其的第二纵向轴线的第二腔。 第二支架主体的端部铰接地接合到第一支架主体的一部分,并且第一管腔和第二管腔彼此流体连通。 支架组件具有未部署和部署状态。 在非部署状态下,第一纵向轴线和第二纵向轴线基本上彼此平行并且第二管腔完全位于第一管腔内。 在展开状态下,第二纵向轴线与第一纵向轴线形成倾斜角度。
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公开(公告)号:US08414632B2
公开(公告)日:2013-04-09
申请号:US11368927
申请日:2006-03-06
申请人: Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
发明人: Angela Kornkven Volk , Karl A. Jagger , Tracee Eidenschink , Richard Olson , John Blix , Derek Sutermeister , Jay Rassat
CPC分类号: A61M25/001 , A61B2017/00398 , A61B2017/00871 , A61M25/0069 , A61M25/0074 , A61M25/10 , A61M2025/0024 , A61M2025/0058 , A61M2025/0063 , A61M2025/09125
摘要: A catheter tip has an outer surface section, an inner surface section, a spatial configuration and at least one segment of electroactive polymer. The inner surface section defines a guide wire lumen. The electroactive polymer has an actuated state and a non-actuated state. In an actuated state, the electroactive polymer alters the spatial configuration of the catheter tip.
摘要翻译: 导管尖端具有外表面部分,内表面部分,空间构造和至少一个电活性聚合物部分。 内表面部分限定导丝管腔。 电活性聚合物具有致动状态和非致动状态。 在致动状态下,电活性聚合物改变导管尖端的空间构型。
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公开(公告)号:US07767726B2
公开(公告)日:2010-08-03
申请号:US11801895
申请日:2007-05-11
申请人: Derek Sutermeister , Jay Rassat
发明人: Derek Sutermeister , Jay Rassat
IPC分类号: A61K6/083
CPC分类号: A61L31/048 , A61L31/10 , Y10T428/261 , Y10T428/2809 , C08L53/00
摘要: According to an aspect of the invention, medical devices are provided which contain at least one polymeric region. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer. Moreover, the polymeric region contains at least one surface sub-region that is crosslinked and at least one bulk sub-region that is substantially non-crosslinked. According to another aspect of the invention, a method is provided which includes exposing a polymeric region of a medical device to energetic species such that at least one surface sub-region of the polymeric region becomes crosslinked and at least one bulk sub-region remains substantially non-crosslinked. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer.
摘要翻译: 根据本发明的一个方面,提供了包含至少一个聚合物区域的医疗装置。 聚合物区域含有至少一种共聚物,其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。 此外,聚合物区域包含至少一个交联的表面亚区域和基本上未交联的至少一个整体亚区域。 根据本发明的另一方面,提供了一种方法,其包括将医疗装置的聚合物区域暴露于能量物质,使得聚合物区域的至少一个表面亚区域变得交联,并且至少一个体积亚区域基本上保持 非交联的。 聚合物区域含有至少一种共聚物,其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。
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公开(公告)号:US20080279911A1
公开(公告)日:2008-11-13
申请号:US11801895
申请日:2007-05-11
申请人: Derek Sutermeister , Jay Rassat
发明人: Derek Sutermeister , Jay Rassat
IPC分类号: A61F2/02 , B32B17/10 , C08F112/02 , C08J3/28 , C08K5/15
CPC分类号: A61L31/048 , A61L31/10 , Y10T428/261 , Y10T428/2809 , C08L53/00
摘要: According to an aspect of the invention, medical devices are provided which contain at least one polymeric region. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer. Moreover, the polymeric region contains at least one surface sub-region that is crosslinked and at least one bulk sub-region that is substantially non-crosslinked. According to another aspect of the invention, a method is provided which includes exposing a polymeric region of a medical device to energetic species such that at least one surface sub-region of the polymeric region becomes crosslinked and at least one bulk sub-region remains substantially non-crosslinked. The polymeric region contains at least one copolymer, which includes at least one high Tg vinyl aromatic monomer and at least one low Tg monomer.
摘要翻译: 根据本发明的一个方面,提供了包含至少一个聚合物区域的医疗装置。 聚合物区域含有至少一种共聚物,其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。 此外,聚合物区域包含至少一个交联的表面亚区域和基本上未交联的至少一个整体亚区域。 根据本发明的另一方面,提供了一种方法,其包括将医疗装置的聚合物区域暴露于能量物质,使得聚合物区域的至少一个表面亚区域变得交联,并且至少一个体积亚区域基本上保持 非交联的。 聚合物区域含有至少一种共聚物,其包括至少一种高Tg乙烯基芳族单体和至少一种低Tg单体。
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公开(公告)号:US20080125706A1
公开(公告)日:2008-05-29
申请号:US11506491
申请日:2006-08-18
申请人: Derek Sutermeister , Jay Rassat , Dan Wefel
发明人: Derek Sutermeister , Jay Rassat , Dan Wefel
IPC分类号: A61M25/082 , A61F2/00 , A61M25/092
CPC分类号: A61M25/0116 , A61M31/00 , A61M2025/0058
摘要: An apparatus for delivery through a vessel including an extensor segment and first and second anchor segments positioned on either side of the extensor segment, wherein each segment has associated with it an individually-addressable electro-active polymer.
摘要翻译: 一种用于通过血管输送的装置,包括伸肌段和位于伸肌段两侧的第一和第二锚定段,其中每个区段与其相关联的是单独寻址的电活性聚合物。
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公开(公告)号:US09242073B2
公开(公告)日:2016-01-26
申请号:US11506491
申请日:2006-08-18
申请人: Derek Sutermeister , Jay Rassat , Dan Wefel
发明人: Derek Sutermeister , Jay Rassat , Dan Wefel
CPC分类号: A61M25/0116 , A61M31/00 , A61M2025/0058
摘要: An apparatus for delivery through a vessel including an extensor segment and first and second anchor segments positioned on either side of the extensor segment, wherein each segment has associated with it an individually-addressable electro-active polymer.
摘要翻译: 一种用于通过血管输送的装置,包括伸肌段和位于伸肌段两侧的第一和第二锚定段,其中每个区段与其相关联的是单独寻址的电活性聚合物。
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