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公开(公告)号：US20180306807A1
公开(公告)日：2018-10-25
申请号：US15769237
申请日：2016-10-19
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Ryan Faucette , Janja Cosic
IPC: G01N33/68 , G01N33/86 , G01N33/543 , C07K16/36
CPC classification number: G01N33/6893 , C07K16/36 , G01N33/54306 , G01N33/86 , G01N2333/745 , G01N2800/50
Abstract: The present disclosure provides immunoassay methods of detecting a cleaved high molecular weight kininogen (HMWK) with high sensitivity and specificity and isolated antibodies that specifically bind cleaved HMWK
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公开(公告)号：US20180305454A1
公开(公告)日：2018-10-25
申请号：US15830998
申请日：2017-12-04
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Christopher TenHoor , Malini Viswanathan
Abstract: The disclosure relates to antibodies that bind FcRn and methods of using these antibodies.
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公开(公告)号：US20180037665A1
公开(公告)日：2018-02-08
申请号：US15706622
申请日：2017-09-15
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Malini Viswanathan
CPC classification number: C07K16/40 , A61K49/0004 , A61K2039/505 , C07K2317/76 , C07K2317/92
Abstract: Plasma kallikrein binding proteins and methods of using such proteins are described.
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公开(公告)号：US09629934B2
公开(公告)日：2017-04-25
申请号：US14019241
申请日：2013-09-05
Applicant: Dyax Corp.
Inventor： Aaron K. Sato , Daniel J. Sexton , Daniel T. Dransfield , Robert Charles Ladner
CPC classification number: A61K49/221 , A61K38/00 , A61K47/62 , A61K49/223 , A61K51/088 , C07K7/08 , C07K14/001 , C07K14/52 , C07K14/71 , C07K2319/00 , Y02A50/411 , Y02A50/58
Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD
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15.发明申请PLASMA KALLIKREIN BINDING PROTEINS AND USES THEREOF IN TREATING HEREDITARY ANGIOEDEMA 审中-公开PLASMA KALLIKREIN结合蛋白及其在治疗放疗中的应用公开(公告)号：US20170002094A1
公开(公告)日：2017-01-05
申请号：US15113297
申请日：2015-01-21
Applicant: DYAX CORP.
Inventor： Daniel J. Sexton , Burt Adelman , Yung Chyung , Christopher TenHoor , Jon A. Kenniston , Ryan Faucette , Rayan larrobino , Joe Biedenkapp
IPC: C07K16/40
CPC classification number: C07K16/40 , A61K2039/505 , A61K2039/545 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Provided herein are plasma kallikrein binding proteins such as antibodies binding to active plasma kallikrein and methods of using such proteins in treating hereditary angioedema.
Abstract translation: 本文提供血浆激肽释放酶结合蛋白，例如结合活性血浆激肽释放酶的抗体以及使用这些蛋白质治疗遗传性血管性水肿的方法。
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Patent Agency Ranking
公开(公告)号：US20160252533A1
公开(公告)日：2016-09-01
申请号：US15030790
申请日：2014-10-17
Applicant: DYAX CORP.
Inventor： Daniel J. Sexton , Burt Adelman , Andrew Nixon
IPC: G01N33/86
CPC classification number: G01N33/86 , G01N33/564 , G01N2333/745 , G01N2333/8139 , G01N2800/065 , G01N2800/102 , G01N2800/52 , G01N2800/56
Abstract: Methods, kits and compositions for diagnosing and treating autoimmune diseases such as rheumatiodi arthritis, Crohn's disease, and ulcerative colitis.
Abstract translation: 用于诊断和治疗自身免疫疾病如风湿性关节炎，克罗恩病和溃疡性结肠炎的方法，试剂盒和组合物。
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公开(公告)号：US11046785B2
公开(公告)日：2021-06-29
申请号：US16541743
申请日：2019-08-15
Applicant: Dyax Corp.
Inventor： Gregory P. Conley , Andrew Nixon , Daniel J. Sexton
Abstract: Disclosed herein are compositions comprising one or more antibodies that specifically bind active plasma kallikrein (e.g., human plasma kallikrein) and methods of using such compositions for the treatment of retinal diseases, such as diabetic macular edema.
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公开(公告)号：US11014988B2
公开(公告)日：2021-05-25
申请号：US16594218
申请日：2019-10-07
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Christopher TenHoor , Malini Viswanathan
Abstract: The disclosure relates to antibodies that bind FcRn and methods of using these antibodies.
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公开(公告)号：US20200371120A1
公开(公告)日：2020-11-26
申请号：US16849492
申请日：2020-04-15
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Burt Adelman , Andrew Nixon
IPC: G01N33/86 , G01N33/564
Abstract: Methods, kits and compositions for diagnosing and treating autoimmue diseases such as rheumatiodi arthritis, Crohn's disease, and ulcerative colitis.
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公开(公告)号：US20200017602A1
公开(公告)日：2020-01-16
申请号：US16445304
申请日：2019-06-19
Applicant: Dyax Corp.
Inventor： Daniel J. Sexton , Malini Viswanathan
IPC: C07K16/40 , G01N33/573
Abstract: Plasma kallikrein binding proteins and methods of using such proteins are described.
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