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公开(公告)号：US20200237504A1
公开(公告)日：2020-07-30
申请号：US16849243
申请日：2020-04-15
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , David J. Evans , Rajesh A. Khanna
IPC: A61F2/24
Abstract: A valve catheter is advanced through a patient's vasculature while a prosthetic heart valve is attached to flexible extensions along a distal end thereof. The valve catheter is advanced through a tubular sleeve for exposing the prosthetic heart valve and allowing the prosthetic heart valve to self-expand while the extensions remain attached to the prosthetic heart valve. A release mechanism on a handle portion is actuated for releasing the prosthetic heart valve from the extensions, thereby implanting the prosthetic heart in a native heart valve. If the operator is not satisfied with the initial expansion, the prosthetic heart valve may be reoriented before release from the extensions by retracting the prosthetic heart valve back into the tubular sleeve, adjusting the orientation of the prosthetic heart valve and then re-advancing the valve catheter from the tubular sleeve for allowing the prosthetic heart valve to re-self-expand at a more desirable location.
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公开(公告)号：US20190091018A1
公开(公告)日：2019-03-28
申请号：US16202980
申请日：2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , A61F2002/9522 , A61F2220/0033 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US20150134052A1
公开(公告)日：2015-05-14
申请号：US14483862
申请日：2014-09-11
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , A61F2002/9522 , A61F2220/0033 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.
Abstract translation: 根据一个实施例的可植入人造瓣膜包括框架，小叶结构和裙部构件。 框架可以具有由多个圆周支柱互连的多个轴向支柱。 小叶结构包括多个传单（例如，安排形成三尖瓣的三个小叶）。 小叶结构具有固定到框架的扇形下边缘部分。 裙部构件可以设置在小叶结构和框架之间。
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公开(公告)号：US12011351B2
公开(公告)日：2024-06-18
申请号：US16849243
申请日：2020-04-15
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , David J. Evans , Rajesh A. Khanna
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
Abstract: A valve catheter is advanced through a patient's vasculature while a prosthetic heart valve is attached to flexible extensions along a distal end thereof. The valve catheter is advanced through a tubular sleeve for exposing the prosthetic heart valve and allowing the prosthetic heart valve to self-expand while the extensions remain attached to the prosthetic heart valve. A release mechanism on a handle portion is actuated for releasing the prosthetic heart valve from the extensions, thereby implanting the prosthetic heart in a native heart valve. If the operator is not satisfied with the initial expansion, the prosthetic heart valve may be reoriented before release from the extensions by retracting the prosthetic heart valve back into the tubular sleeve, adjusting the orientation of the prosthetic heart valve and then re-advancing the valve catheter from the tubular sleeve for allowing the prosthetic heart valve to re-self-expand at a more desirable location.
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公开(公告)号：US20230363902A1
公开(公告)日：2023-11-16
申请号：US18223441
申请日：2023-07-18
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/95 , B05B1/185 , E03C1/025 , E03C1/066 , A61F2/2475 , Y10T29/49863 , A61F2220/0075 , A61F2220/005 , A61F2230/0054 , A61F2/9522 , A61F2220/0033
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment portions and at least three rows of angled struts. The rows include a first row, a second row downstream of the first row, and a third row downstream of the second row. Each row of struts includes angled struts arranged in a zig-zag pattern defining a plurality of crowns. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment portions via sutures extending through apertures in the commissure attachment portions, wherein all of the apertures are located along the length of the frame between a first plane defined by the crowns of the second row of struts and a second plane defined by the crowns of the third row of struts.
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Patent Agency Ranking
公开(公告)号：US11744701B2
公开(公告)日：2023-09-05
申请号：US17018258
申请日：2020-09-11
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , B05B1/185 , E03C1/025 , E03C1/066 , A61F2/9522 , A61F2220/005 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: A prosthetic heart valve comprises a radially collapsible and expandable annular frame and a leaflet structure comprising three leaflets. Each leaflet has an upper edge portion, a curved lower edge portion and two side flaps, wherein each side flap is connected to an adjacent side flap of another leaflet to form commissures of the leaflet structure, with each commissure being attached to the frame. An annular inner sleeve comprises three U-shaped portions positioned along the curved lower edge portions of the leaflets. An annular outer sleeve extends around are outer surface of the frame, wherein the outer sleeve is made of pericardium. The frame is made of Nitinol and the prosthetic valve can be radially crimped to a radially collapsed configuration inside a sheath for delivery into a patient's body and self-expand to a radially expanded configuration when released from the sheath inside the patient's body.
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公开(公告)号：US11696826B2
公开(公告)日：2023-07-11
申请号：US17704660
申请日：2022-03-25
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , B05B1/185 , E03C1/025 , E03C1/066 , A61F2/9522 , A61F2220/005 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号：US10426611B2
公开(公告)日：2019-10-01
申请号：US16202980
申请日：2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US10299923B2
公开(公告)日：2019-05-28
申请号：US16202980
申请日：2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US09839514B2
公开(公告)日：2017-12-12
申请号：US15347505
申请日：2016-11-09
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
Abstract: An assembly for treating a native heart valve can include a prosthetic valve and a delivery apparatus. The prosthetic valve can include an expandable frame, a valve structure, a first end with apertures formed therein, and a second end. The delivery apparatus can include a valve catheter, flexible extension arms, slidable wires, and release members. First ends of the arms can be coupled to a cylindrical coupling element, second ends of the arms can be releasably coupled to the prosthetic valve, and the coupling element can be connected to the distal end of the valve catheter. The slidable wires can extend distally from the distal end of the valve catheter. The release members can be coupled to the distal end of the valve catheter and can extend through a respective aperture of the prosthetic valve, thereby forming a releasable connection between the prosthetic valve and the slidable wires.
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